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Results: 1 to 20 of 102

1.

Two proteolytic pathways regulate DNA repair by cotargeting the Mgt1 alkylguanine transferase.

Hwang CS, Shemorry A, Varshavsky A.

Proc Natl Acad Sci U S A. 2009 Feb 17;106(7):2142-7. doi: 10.1073/pnas.0812316106. Epub 2009 Jan 21.

PMID:
19164530
[PubMed - indexed for MEDLINE]
Free PMC Article
2.
3.

The N-end rule pathway is mediated by a complex of the RING-type Ubr1 and HECT-type Ufd4 ubiquitin ligases.

Hwang CS, Shemorry A, Auerbach D, Varshavsky A.

Nat Cell Biol. 2010 Dec;12(12):1177-85. doi: 10.1038/ncb2121. Epub 2010 Nov 14.

PMID:
21076411
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Degradation of the alkylated form of the DNA repair protein, O(6)-alkylguanine-DNA alkyltransferase.

Xu-Welliver M, Pegg AE.

Carcinogenesis. 2002 May;23(5):823-30.

PMID:
12016156
[PubMed - indexed for MEDLINE]
Free Article
5.

DNA mismatch repair mutants do not increase N-methyl-N'-nitro-N-nitrosoguanidine tolerance in O6-methylguanine DNA methyltransferase-deficient yeast cells.

Xiao W, Rathgeber L, Fontanie T, Bawa S.

Carcinogenesis. 1995 Aug;16(8):1933-9.

PMID:
7634424
[PubMed - indexed for MEDLINE]
6.

Investigation of the role of tyrosine-114 in the activity of human O6-alkylguanine-DNA alkyltranferase.

Goodtzova K, Kanugula S, Edara S, Pegg AE.

Biochemistry. 1998 Sep 8;37(36):12489-95.

PMID:
9730821
[PubMed - indexed for MEDLINE]
7.

Function of domains of human O6-alkylguanine-DNA alkyltransferase.

Fang Q, Kanugula S, Pegg AE.

Biochemistry. 2005 Nov 22;44(46):15396-405.

PMID:
16285744
[PubMed - indexed for MEDLINE]
8.

REV3 is required for spontaneous but not methylation damage-induced mutagenesis of Saccharomyces cerevisiae cells lacking O6-methylguanine DNA methyltransferase.

Xiao W, Fontanie T, Bawa S, Kohalmi L.

Mutat Res. 1999 Dec 16;431(1):155-65.

PMID:
10656494
[PubMed - indexed for MEDLINE]
9.

Inactivation and degradation of O(6)-alkylguanine-DNA alkyltransferase after reaction with nitric oxide.

Liu L, Xu-Welliver M, Kanugula S, Pegg AE.

Cancer Res. 2002 Jun 1;62(11):3037-43.

PMID:
12036910
[PubMed - indexed for MEDLINE]
Free Article
10.

Inhibition of O6-methylguanine-DNA methyltransferase by an alkyltransferase-like protein from Escherichia coli.

Pearson SJ, Ferguson J, Santibanez-Koref M, Margison GP.

Nucleic Acids Res. 2005 Jul 13;33(12):3837-44. Print 2005.

PMID:
16027108
[PubMed - indexed for MEDLINE]
Free PMC Article
11.
12.

Specific complex formation between yeast RAD6 and RAD18 proteins: a potential mechanism for targeting RAD6 ubiquitin-conjugating activity to DNA damage sites.

Bailly V, Lamb J, Sung P, Prakash S, Prakash L.

Genes Dev. 1994 Apr 1;8(7):811-20.

PMID:
7926769
[PubMed - indexed for MEDLINE]
Free Article
13.

Topoisomerase I-mediated cytotoxicity of N-methyl-N'-nitro-N-nitrosoguanidine: trapping of topoisomerase I by the O6-methylguanine.

Pourquier P, Waltman JL, Urasaki Y, Loktionova NA, Pegg AE, Nitiss JL, Pommier Y.

Cancer Res. 2001 Jan 1;61(1):53-8.

PMID:
11196197
[PubMed - indexed for MEDLINE]
Free Article
14.

A synthetic defect in protein degradation caused by loss of Ufd4 and Rad23.

Ju D, Xie Y.

Biochem Biophys Res Commun. 2006 Mar 10;341(2):648-52. Epub 2006 Jan 17.

PMID:
16430867
[PubMed - indexed for MEDLINE]
15.

The N-end rule is mediated by the UBC2(RAD6) ubiquitin-conjugating enzyme.

Dohmen RJ, Madura K, Bartel B, Varshavsky A.

Proc Natl Acad Sci U S A. 1991 Aug 15;88(16):7351-5.

PMID:
1651502
[PubMed - indexed for MEDLINE]
Free PMC Article
16.
17.
18.

The repair of the tobacco specific nitrosamine derived adduct O6-[4-Oxo-4-(3-pyridyl)butyl]guanine by O6-alkylguanine-DNA alkyltransferase variants.

Mijal RS, Thomson NM, Fleischer NL, Pauly GT, Moschel RC, Kanugula S, Fang Q, Pegg AE, Peterson LA.

Chem Res Toxicol. 2004 Mar;17(3):424-34.

PMID:
15025514
[PubMed - indexed for MEDLINE]
19.

DNA sequence context affects repair of the tobacco-specific adduct O(6)-[4-Oxo-4-(3-pyridyl)butyl]guanine by human O(6)-alkylguanine-DNA alkyltransferases.

Mijal RS, Kanugula S, Vu CC, Fang Q, Pegg AE, Peterson LA.

Cancer Res. 2006 May 1;66(9):4968-74.

PMID:
16651455
[PubMed - indexed for MEDLINE]
Free Article
20.

Brca2/Xrcc2 dependent HR, but not NHEJ, is required for protection against O(6)-methylguanine triggered apoptosis, DSBs and chromosomal aberrations by a process leading to SCEs.

Roos WP, Nikolova T, Quiros S, Naumann SC, Kiedron O, Zdzienicka MZ, Kaina B.

DNA Repair (Amst). 2009 Jan 1;8(1):72-86. doi: 10.1016/j.dnarep.2008.09.003. Epub 2008 Oct 21.

PMID:
18840549
[PubMed - indexed for MEDLINE]

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