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Items: 1 to 20 of 114

1.

Hypoxia-induced lysyl oxidase is a critical mediator of bone marrow cell recruitment to form the premetastatic niche.

Erler JT, Bennewith KL, Cox TR, Lang G, Bird D, Koong A, Le QT, Giaccia AJ.

Cancer Cell. 2009 Jan 6;15(1):35-44. doi: 10.1016/j.ccr.2008.11.012.

3.

Lysyl oxidase is essential for hypoxia-induced metastasis.

Erler JT, Bennewith KL, Nicolau M, Dornhöfer N, Kong C, Le QT, Chi JT, Jeffrey SS, Giaccia AJ.

Nature. 2006 Apr 27;440(7088):1222-6.

PMID:
16642001
4.

Inhibitors of hypoxia-inducible factor 1 block breast cancer metastatic niche formation and lung metastasis.

Wong CC, Zhang H, Gilkes DM, Chen J, Wei H, Chaturvedi P, Hubbi ME, Semenza GL.

J Mol Med (Berl). 2012 Jul;90(7):803-15. doi: 10.1007/s00109-011-0855-y. Epub 2012 Jan 10.

5.

Hypoxia/reoxygenation: a dynamic regulator of lysyl oxidase-facilitated breast cancer migration.

Postovit LM, Abbott DE, Payne SL, Wheaton WW, Margaryan NV, Sullivan R, Jansen MK, Csiszar K, Hendrix MJ, Kirschmann DA.

J Cell Biochem. 2008 Apr 1;103(5):1369-78.

PMID:
17685448
6.

The role of lysyl oxidase in SRC-dependent proliferation and metastasis of colorectal cancer.

Baker AM, Cox TR, Bird D, Lang G, Murray GI, Sun XF, Southall SM, Wilson JR, Erler JT.

J Natl Cancer Inst. 2011 Mar 2;103(5):407-24. doi: 10.1093/jnci/djq569. Epub 2011 Jan 31.

7.

Hypoxia-inducible factor 1 is a master regulator of breast cancer metastatic niche formation.

Wong CC, Gilkes DM, Zhang H, Chen J, Wei H, Chaturvedi P, Fraley SI, Wong CM, Khoo US, Ng IO, Wirtz D, Semenza GL.

Proc Natl Acad Sci U S A. 2011 Sep 27;108(39):16369-74. doi: 10.1073/pnas.1113483108. Epub 2011 Sep 12.

8.

Pdcd4 repression of lysyl oxidase inhibits hypoxia-induced breast cancer cell invasion.

Santhanam AN, Baker AR, Hegamyer G, Kirschmann DA, Colburn NH.

Oncogene. 2010 Jul 8;29(27):3921-32. doi: 10.1038/onc.2010.158. Epub 2010 May 24.

9.

Lysyl oxidase may play a critical role in hypoxia-induced NSCLC cells invasion and migration.

Wei L, Song XR, Sun JJ, Wang XW, Xie L, Lv LY.

Cancer Biother Radiopharm. 2012 Dec;27(10):672-7. doi: 10.1089/cbr.2012.1241. Epub 2012 Nov 9.

10.

The hypoxic cancer secretome induces pre-metastatic bone lesions through lysyl oxidase.

Cox TR, Rumney RM, Schoof EM, Perryman L, Høye AM, Agrawal A, Bird D, Latif NA, Forrest H, Evans HR, Huggins ID, Lang G, Linding R, Gartland A, Erler JT.

Nature. 2015 Jun 4;522(7554):106-10. doi: 10.1038/nature14492. Epub 2015 May 27.

11.

Human breast cancer cell metastasis is attenuated by lysyl oxidase inhibitors through down-regulation of focal adhesion kinase and the paxillin-signaling pathway.

Chen LC, Tu SH, Huang CS, Chen CS, Ho CT, Lin HW, Lee CH, Chang HW, Chang CH, Wu CH, Lee WS, Ho YS.

Breast Cancer Res Treat. 2012 Aug;134(3):989-1004. doi: 10.1007/s10549-012-1986-8. Epub 2012 Mar 21.

PMID:
22434522
12.

Ionizing radiation induces tumor cell lysyl oxidase secretion.

Shen CJ, Sharma A, Vuong DV, Erler JT, Pruschy M, Broggini-Tenzer A.

BMC Cancer. 2014 Jul 22;14:532. doi: 10.1186/1471-2407-14-532.

13.

A molecular role for lysyl oxidase in breast cancer invasion.

Kirschmann DA, Seftor EA, Fong SF, Nieva DR, Sullivan CM, Edwards EM, Sommer P, Csiszar K, Hendrix MJ.

Cancer Res. 2002 Aug 1;62(15):4478-83.

14.

[Mechanism of lysyl oxidase (LOX) in breast cancer invasion and metastasis].

Liu JL, Wei W, Tang W, Jiang Y, Yang HW, Li JT.

Zhonghua Yi Xue Za Zhi. 2012 May 29;92(20):1379-83. Chinese.

PMID:
22883193
15.

Lysyl oxidase secreted by tumour endothelial cells promotes angiogenesis and metastasis.

Osawa T, Ohga N, Akiyama K, Hida Y, Kitayama K, Kawamoto T, Yamamoto K, Maishi N, Kondoh M, Onodera Y, Fujie M, Shinohara N, Nonomura K, Shindoh M, Hida K.

Br J Cancer. 2013 Oct 15;109(8):2237-47. doi: 10.1038/bjc.2013.535. Epub 2013 Sep 17.

16.

The HIF-1-inducible lysyl oxidase activates HIF-1 via the Akt pathway in a positive regulation loop and synergizes with HIF-1 in promoting tumor cell growth.

Pez F, Dayan F, Durivault J, Kaniewski B, Aimond G, Le Provost GS, Deux B, Clézardin P, Sommer P, Pouysségur J, Reynaud C.

Cancer Res. 2011 Mar 1;71(5):1647-57. doi: 10.1158/0008-5472.CAN-10-1516. Epub 2011 Jan 14.

17.

Myeloid progenitor cells in the premetastatic lung promote metastases by inducing mesenchymal to epithelial transition.

Gao D, Joshi N, Choi H, Ryu S, Hahn M, Catena R, Sadik H, Argani P, Wagner P, Vahdat LT, Port JL, Stiles B, Sukumar S, Altorki NK, Rafii S, Mittal V.

Cancer Res. 2012 Mar 15;72(6):1384-94. doi: 10.1158/0008-5472.CAN-11-2905. Epub 2012 Jan 26.

18.

The lysyl oxidase pro-peptide attenuates fibronectin-mediated activation of focal adhesion kinase and p130Cas in breast cancer cells.

Zhao Y, Min C, Vora SR, Trackman PC, Sonenshein GE, Kirsch KH.

J Biol Chem. 2009 Jan 16;284(3):1385-93. doi: 10.1074/jbc.M802612200. Epub 2008 Nov 21.

19.

Critical role for lysyl oxidase in mesenchymal stem cell-driven breast cancer malignancy.

El-Haibi CP, Bell GW, Zhang J, Collmann AY, Wood D, Scherber CM, Csizmadia E, Mariani O, Zhu C, Campagne A, Toner M, Bhatia SN, Irimia D, Vincent-Salomon A, Karnoub AE.

Proc Natl Acad Sci U S A. 2012 Oct 23;109(43):17460-5. doi: 10.1073/pnas.1206653109. Epub 2012 Oct 2.

20.

Silencing of lysyl oxidase gene expression by RNA interference suppresses metastasis of breast cancer.

Liu JL, Wei W, Tang W, Jiang Y, Yang HW, Li JT, Zhou X.

Asian Pac J Cancer Prev. 2012;13(7):3507-11.

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