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Results: 1 to 20 of 72

1.

Monitoring for lack of benefit: a critical component of a randomized clinical trial.

Freidlin B, Korn EL.

J Clin Oncol. 2009 Feb 1;27(4):629-33. doi: 10.1200/JCO.2008.17.8905. Epub 2008 Dec 8.

PMID:
19064977
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

A general inefficacy interim monitoring rule for randomized clinical trials.

Freidlin B, Korn EL, Gray R.

Clin Trials. 2010 Jun;7(3):197-208. doi: 10.1177/1740774510369019. Epub 2010 Apr 27.

PMID:
20423925
[PubMed - indexed for MEDLINE]
3.

A comment on futility monitoring.

Freidlin B, Korn EL.

Control Clin Trials. 2002 Aug;23(4):355-66.

PMID:
12161079
[PubMed - indexed for MEDLINE]
4.

Data monitoring committees and interim monitoring guidelines.

Freidlin B, Korn EL, George SL.

Control Clin Trials. 1999 Oct;20(5):395-407. Review.

PMID:
10503800
[PubMed - indexed for MEDLINE]
5.

Issues in data monitoring and interim analysis of trials.

Grant AM, Altman DG, Babiker AB, Campbell MK, Clemens FJ, Darbyshire JH, Elbourne DR, McLeer SK, Parmar MK, Pocock SJ, Spiegelhalter DJ, Sydes MR, Walker AE, Wallace SA; DAMOCLES study group.

Health Technol Assess. 2005 Mar;9(7):1-238, iii-iv. Review.

PMID:
15763038
[PubMed - indexed for MEDLINE]
Free Article
6.

Specific barriers to the conduct of randomized trials.

Duley L, Antman K, Arena J, Avezum A, Blumenthal M, Bosch J, Chrolavicius S, Li T, Ounpuu S, Perez AC, Sleight P, Svard R, Temple R, Tsouderous Y, Yunis C, Yusuf S.

Clin Trials. 2008;5(1):40-8. doi: 10.1177/1740774507087704.

PMID:
18283079
[PubMed - indexed for MEDLINE]
7.

Recruitment to randomised trials: strategies for trial enrollment and participation study. The STEPS study.

Campbell MK, Snowdon C, Francis D, Elbourne D, McDonald AM, Knight R, Entwistle V, Garcia J, Roberts I, Grant A, Grant A; STEPS group.

Health Technol Assess. 2007 Nov;11(48):iii, ix-105. Review.

PMID:
17999843
[PubMed - indexed for MEDLINE]
Free Article
8.

Beyond HERS: some (not so) random thoughts on randomized clinical trials.

Bush T.

Int J Fertil Womens Med. 2001 Mar-Apr;46(2):55-9.

PMID:
11374656
[PubMed - indexed for MEDLINE]
9.

Futility approaches to interim monitoring by data monitoring committees.

Demets DL.

Clin Trials. 2006;3(6):522-9. Review.

PMID:
17170036
[PubMed - indexed for MEDLINE]
10.

Generalizing results of randomized trials to clinical practice: reliability and cautions.

Flather M, Delahunty N, Collinson J.

Clin Trials. 2006;3(6):508-12. Review.

PMID:
17170034
[PubMed - indexed for MEDLINE]
11.

Evidence-based medicine, systematic reviews, and guidelines in interventional pain management: Part 2: Randomized controlled trials.

Manchikanti L, Hirsch JA, Smith HS.

Pain Physician. 2008 Nov-Dec;11(6):717-73. Review.

PMID:
19057624
[PubMed - indexed for MEDLINE]
Free Article
12.

Early stopping of a clinical trial when there is evidence of no treatment benefit: protocol B-14 of the National Surgical Adjuvant Breast and Bowel Project.

Dignam JJ, Bryant J, Wieand HS, Fisher B, Wolmark N.

Control Clin Trials. 1998 Dec;19(6):575-88.

PMID:
9875837
[PubMed - indexed for MEDLINE]
13.

Are randomized clinical trials good for us (in the short term)? Evidence for a "trial effect".

Braunholtz DA, Edwards SJ, Lilford RJ.

J Clin Epidemiol. 2001 Mar;54(3):217-24. Review.

PMID:
11223318
[PubMed - indexed for MEDLINE]
14.

Continuous safety monitoring for randomized controlled clinical trials with blinded treatment information. Part 1: Ethical considerations.

Ball G, Piller LB, Silverman MH.

Contemp Clin Trials. 2011 Sep;32 Suppl 1:S2-4. doi: 10.1016/j.cct.2011.05.010. Epub 2011 Jun 6.

PMID:
21664987
[PubMed - indexed for MEDLINE]
15.

[Controlled randomized clinical trials].

Jaillon P.

Bull Acad Natl Med. 2007 Apr-May;191(4-5):739-56; discussion 756-8. French.

PMID:
18225427
[PubMed - indexed for MEDLINE]
16.

Issues in clinical trial design: stopping a trial early and the large and simple trial.

Thom EA, Klebanoff MA.

Am J Obstet Gynecol. 2005 Sep;193(3 Pt 1):619-25.

PMID:
16150252
[PubMed - indexed for MEDLINE]
17.

Current controversies in data monitoring for clinical trials.

Pocock SJ.

Clin Trials. 2006;3(6):513-21.

PMID:
17170035
[PubMed - indexed for MEDLINE]
18.

Ethical issues in stopping randomized trials early because of apparent benefit.

Mueller PS, Montori VM, Bassler D, Koenig BA, Guyatt GH.

Ann Intern Med. 2007 Jun 19;146(12):878-81.

PMID:
17577007
[PubMed - indexed for MEDLINE]
19.

Design of treatment trials for functional gastrointestinal disorders.

Veldhuyzen van Zanten SJ, Talley NJ, Bytzer P, Klein KB, Whorwell PJ, Zinsmeister AR.

Gut. 1999 Sep;45 Suppl 2:II69-77.

PMID:
10457048
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Are distinctive ethical principles required for cluster randomized controlled trials?

Hutton JL.

Stat Med. 2001 Feb 15;20(3):473-88.

PMID:
11180314
[PubMed - indexed for MEDLINE]

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