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Results: 1 to 20 of 114

1.

PERK-dependent regulation of IAP translation during ER stress.

Hamanaka RB, Bobrovnikova-Marjon E, Ji X, Liebhaber SA, Diehl JA.

Oncogene. 2009 Feb 12;28(6):910-20. doi: 10.1038/onc.2008.428. Epub 2008 Nov 24.

PMID:
19029953
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Endoplasmic reticulum (ER) chaperone regulation and survival of cells compensating for deficiency in the ER stress response kinase, PERK.

Yamaguchi Y, Larkin D, Lara-Lemus R, Ramos-Castañeda J, Liu M, Arvan P.

J Biol Chem. 2008 Jun 20;283(25):17020-9. doi: 10.1074/jbc.M802466200. Epub 2008 Apr 21.

PMID:
18426796
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

The eIF2 kinase PERK and the integrated stress response facilitate activation of ATF6 during endoplasmic reticulum stress.

Teske BF, Wek SA, Bunpo P, Cundiff JK, McClintick JN, Anthony TG, Wek RC.

Mol Biol Cell. 2011 Nov;22(22):4390-405. doi: 10.1091/mbc.E11-06-0510. Epub 2011 Sep 14.

PMID:
21917591
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Regulation of protein synthesis by hypoxia via activation of the endoplasmic reticulum kinase PERK and phosphorylation of the translation initiation factor eIF2alpha.

Koumenis C, Naczki C, Koritzinsky M, Rastani S, Diehl A, Sonenberg N, Koromilas A, Wouters BG.

Mol Cell Biol. 2002 Nov;22(21):7405-16.

PMID:
12370288
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Calcineurin interacts with PERK and dephosphorylates calnexin to relieve ER stress in mammals and frogs.

Bollo M, Paredes RM, Holstein D, Zheleznova N, Camacho P, Lechleiter JD.

PLoS One. 2010 Aug 5;5(8):e11925. doi: 10.1371/journal.pone.0011925.

PMID:
20700529
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

PERK (eIF2alpha kinase) is required to activate the stress-activated MAPKs and induce the expression of immediate-early genes upon disruption of ER calcium homoeostasis.

Liang SH, Zhang W, McGrath BC, Zhang P, Cavener DR.

Biochem J. 2006 Jan 1;393(Pt 1):201-9.

PMID:
16124869
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Translational control during endoplasmic reticulum stress beyond phosphorylation of the translation initiation factor eIF2α.

Guan BJ, Krokowski D, Majumder M, Schmotzer CL, Kimball SR, Merrick WC, Koromilas AE, Hatzoglou M.

J Biol Chem. 2014 May 2;289(18):12593-611. doi: 10.1074/jbc.M113.543215. Epub 2014 Mar 19.

PMID:
24648524
[PubMed - indexed for MEDLINE]
8.

Critical role of endogenous Akt/IAPs and MEK1/ERK pathways in counteracting endoplasmic reticulum stress-induced cell death.

Hu P, Han Z, Couvillon AD, Exton JH.

J Biol Chem. 2004 Nov 19;279(47):49420-9. Epub 2004 Aug 31.

PMID:
15339911
[PubMed - indexed for MEDLINE]
Free Article
9.

Perk-dependent repression of miR-106b-25 cluster is required for ER stress-induced apoptosis.

Gupta S, Read DE, Deepti A, Cawley K, Gupta A, Oommen D, Verfaillie T, Matus S, Smith MA, Mott JL, Agostinis P, Hetz C, Samali A.

Cell Death Dis. 2012 Jun 28;3:e333. doi: 10.1038/cddis.2012.74.

PMID:
22739985
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Endoplasmic reticulum stress-induced cysteine protease activation in cortical neurons: effect of an Alzheimer's disease-linked presenilin-1 knock-in mutation.

Siman R, Flood DG, Thinakaran G, Neumar RW.

J Biol Chem. 2001 Nov 30;276(48):44736-43. Epub 2001 Sep 26.

PMID:
11574534
[PubMed - indexed for MEDLINE]
Free Article
11.

Carbon monoxide induces heme oxygenase-1 via activation of protein kinase R-like endoplasmic reticulum kinase and inhibits endothelial cell apoptosis triggered by endoplasmic reticulum stress.

Kim KM, Pae HO, Zheng M, Park R, Kim YM, Chung HT.

Circ Res. 2007 Oct 26;101(9):919-27. Epub 2007 Sep 6.

PMID:
17823375
[PubMed - indexed for MEDLINE]
Free Article
12.

Endoplasmic reticulum stress signaling is involved in mitomycin C (MMC)-induced apoptosis in human fibroblasts via PERK pathway.

Shi K, Wang D, Cao X, Ge Y.

PLoS One. 2013;8(3):e59330. doi: 10.1371/journal.pone.0059330. Epub 2013 Mar 22.

PMID:
23533616
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Endoplasmic reticulum stress response mediated by the PERK-eIF2(alpha)-ATF4 pathway is involved in osteoblast differentiation induced by BMP2.

Saito A, Ochiai K, Kondo S, Tsumagari K, Murakami T, Cavener DR, Imaizumi K.

J Biol Chem. 2011 Feb 11;286(6):4809-18. doi: 10.1074/jbc.M110.152900. Epub 2010 Dec 6.

PMID:
21135100
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Control of PERK eIF2alpha kinase activity by the endoplasmic reticulum stress-induced molecular chaperone P58IPK.

Yan W, Frank CL, Korth MJ, Sopher BL, Novoa I, Ron D, Katze MG.

Proc Natl Acad Sci U S A. 2002 Dec 10;99(25):15920-5. Epub 2002 Nov 22.

PMID:
12446838
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Nrf2 is a direct PERK substrate and effector of PERK-dependent cell survival.

Cullinan SB, Zhang D, Hannink M, Arvisais E, Kaufman RJ, Diehl JA.

Mol Cell Biol. 2003 Oct;23(20):7198-209.

PMID:
14517290
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Replication of a cytopathic strain of bovine viral diarrhea virus activates PERK and induces endoplasmic reticulum stress-mediated apoptosis of MDBK cells.

Jordan R, Wang L, Graczyk TM, Block TM, Romano PR.

J Virol. 2002 Oct;76(19):9588-99.

PMID:
12208938
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Ghrelin suppresses tunicamycin- or thapsigargin-triggered endoplasmic reticulum stress-mediated apoptosis in primary cultured rat cortical neuronal cells.

Chung H, Chung HY, Bae CW, Kim CJ, Park S.

Endocr J. 2011;58(5):409-20. Epub 2011 Apr 14.

PMID:
21490406
[PubMed - indexed for MEDLINE]
Free Article
18.

Endoplasmic reticulum stress induced by aqueous extracts of cigarette smoke in 3T3 cells activates the unfolded-protein-response-dependent PERK pathway of cell survival.

Hengstermann A, Müller T.

Free Radic Biol Med. 2008 Mar 15;44(6):1097-107. doi: 10.1016/j.freeradbiomed.2007.12.009. Epub 2007 Dec 23.

PMID:
18206657
[PubMed - indexed for MEDLINE]
19.

ER stress sensitizes cells to TRAIL through down-regulation of FLIP and Mcl-1 and PERK-dependent up-regulation of TRAIL-R2.

Martín-Pérez R, Niwa M, López-Rivas A.

Apoptosis. 2012 Apr;17(4):349-63. doi: 10.1007/s10495-011-0673-2.

PMID:
22072062
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Regulation of subtilase cytotoxin-induced cell death by an RNA-dependent protein kinase-like endoplasmic reticulum kinase-dependent proteasome pathway in HeLa cells.

Yahiro K, Tsutsuki H, Ogura K, Nagasawa S, Moss J, Noda M.

Infect Immun. 2012 May;80(5):1803-14. doi: 10.1128/IAI.06164-11. Epub 2012 Feb 21.

PMID:
22354021
[PubMed - indexed for MEDLINE]
Free PMC Article

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