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Items: 1 to 20 of 106

1.

The guanine nucleotide exchange factors trio, Ect2, and Vav3 mediate the invasive behavior of glioblastoma.

Salhia B, Tran NL, Chan A, Wolf A, Nakada M, Rutka F, Ennis M, McDonough WS, Berens ME, Symons M, Rutka JT.

Am J Pathol. 2008 Dec;173(6):1828-38. doi: 10.2353/ajpath.2008.080043. Epub 2008 Nov 13.

2.

Cdc42 and the guanine nucleotide exchange factors Ect2 and trio mediate Fn14-induced migration and invasion of glioblastoma cells.

Fortin SP, Ennis MJ, Schumacher CA, Zylstra-Diegel CR, Williams BO, Ross JT, Winkles JA, Loftus JC, Symons MH, Tran NL.

Mol Cancer Res. 2012 Jul;10(7):958-68. doi: 10.1158/1541-7786.MCR-11-0616. Epub 2012 May 9.

3.

The Rho protein exchange factor Vav3 regulates vascular smooth muscle cell proliferation and migration.

Toumaniantz G, Ferland-McCollough D, Cario-Toumaniantz C, Pacaud P, Loirand G.

Cardiovasc Res. 2010 Apr 1;86(1):131-40. doi: 10.1093/cvr/cvp387. Epub 2009 Dec 7.

5.

Guanine nucleotide exchange factor Dock7 mediates HGF-induced glioblastoma cell invasion via Rac activation.

Murray DW, Didier S, Chan A, Paulino V, Van Aelst L, Ruggieri R, Tran NL, Byrne AT, Symons M.

Br J Cancer. 2014 Mar 4;110(5):1307-15. doi: 10.1038/bjc.2014.39. Epub 2014 Feb 11.

6.

Mechanisms of guanine nucleotide exchange and Rac-mediated signaling revealed by a dominant negative trio mutant.

Debreceni B, Gao Y, Guo F, Zhu K, Jia B, Zheng Y.

J Biol Chem. 2004 Jan 30;279(5):3777-86. Epub 2003 Nov 3.

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Essential role of Vav family guanine nucleotide exchange factors in EphA receptor-mediated angiogenesis.

Hunter SG, Zhuang G, Brantley-Sieders D, Swat W, Cowan CW, Chen J.

Mol Cell Biol. 2006 Jul;26(13):4830-42.

9.

The small GTPase RhoG mediates glioblastoma cell invasion.

Kwiatkowska A, Didier S, Fortin S, Chuang Y, White T, Berens ME, Rushing E, Eschbacher J, Tran NL, Chan A, Symons M.

Mol Cancer. 2012 Sep 11;11:65. doi: 10.1186/1476-4598-11-65.

10.

Expression level of ECT2 proto-oncogene correlates with prognosis in glioma patients.

Sano M, Genkai N, Yajima N, Tsuchiya N, Homma J, Tanaka R, Miki T, Yamanaka R.

Oncol Rep. 2006 Nov;16(5):1093-8.

PMID:
17016598
11.

The many faces of the guanine-nucleotide exchange factor trio.

van Rijssel J, van Buul JD.

Cell Adh Migr. 2012 Nov-Dec;6(6):482-7. doi: 10.4161/cam.21418. Epub 2012 Oct 17. Review.

12.

Vav3-rac1 signaling regulates prostate cancer metastasis with elevated Vav3 expression correlating with prostate cancer progression and posttreatment recurrence.

Lin KT, Gong J, Li CF, Jang TH, Chen WL, Chen HJ, Wang LH.

Cancer Res. 2012 Jun 15;72(12):3000-9. doi: 10.1158/0008-5472.CAN-11-2502. Epub 2012 Jun 1.

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Identification of novel neuronal isoforms of the Rho-GEF Trio.

Portales-Casamar E, Briançon-Marjollet A, Fromont S, Triboulet R, Debant A.

Biol Cell. 2006 Mar;98(3):183-93.

PMID:
16033331
16.

Ephrin-B3 ligand promotes glioma invasion through activation of Rac1.

Nakada M, Drake KL, Nakada S, Niska JA, Berens ME.

Cancer Res. 2006 Sep 1;66(17):8492-500.

17.

Trp(56) of rac1 specifies interaction with a subset of guanine nucleotide exchange factors.

Gao Y, Xing J, Streuli M, Leto TL, Zheng Y.

J Biol Chem. 2001 Dec 14;276(50):47530-41. Epub 2001 Oct 10. Erratum in: J Biol Chem. 2005 Jan 14;280(2):1704.

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How Vav proteins discriminate the GTPases Rac1 and RhoA from Cdc42.

Movilla N, Dosil M, Zheng Y, Bustelo XR.

Oncogene. 2001 Dec 6;20(56):8057-65.

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