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Results: 1 to 20 of 122

1.

Mouse models of cystathionine beta-synthase deficiency reveal significant threshold effects of hyperhomocysteinemia.

Gupta S, Kühnisch J, Mustafa A, Lhotak S, Schlachterman A, Slifker MJ, Klein-Szanto A, High KA, Austin RC, Kruger WD.

FASEB J. 2009 Mar;23(3):883-93. doi: 10.1096/fj.08-120584. Epub 2008 Nov 5.

PMID:
18987302
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Cystathionine beta-synthase p.S466L mutation causes hyperhomocysteinemia in mice.

Gupta S, Wang L, Hua X, Krijt J, Kozich V, Kruger WD.

Hum Mutat. 2008 Aug;29(8):1048-54. doi: 10.1002/humu.20773.

PMID:
18454451
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Expression of mutant human cystathionine beta-synthase rescues neonatal lethality but not homocystinuria in a mouse model.

Wang L, Chen X, Tang B, Hua X, Klein-Szanto A, Kruger WD.

Hum Mol Genet. 2005 Aug 1;14(15):2201-8. Epub 2005 Jun 22.

PMID:
15972722
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Hyperhomocysteinemia promotes inflammatory monocyte generation and accelerates atherosclerosis in transgenic cystathionine beta-synthase-deficient mice.

Zhang D, Jiang X, Fang P, Yan Y, Song J, Gupta S, Schafer AI, Durante W, Kruger WD, Yang X, Wang H.

Circulation. 2009 Nov 10;120(19):1893-902. doi: 10.1161/CIRCULATIONAHA.109.866889. Epub 2009 Oct 26.

PMID:
19858416
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Hyperhomocysteinemia due to cystathionine beta synthase deficiency induces dysregulation of genes involved in hepatic lipid homeostasis in mice.

Hamelet J, Demuth K, Paul JL, Delabar JM, Janel N.

J Hepatol. 2007 Jan;46(1):151-9. Epub 2006 Sep 22.

PMID:
17030070
[PubMed - indexed for MEDLINE]
6.

Folate dependence of hyperhomocysteinemia and vascular dysfunction in cystathionine beta-synthase-deficient mice.

Lentz SR, Erger RA, Dayal S, Maeda N, Malinow MR, Heistad DD, Faraci FM.

Am J Physiol Heart Circ Physiol. 2000 Sep;279(3):H970-5.

PMID:
10993757
[PubMed - indexed for MEDLINE]
Free Article
7.

Endothelial dysfunction and elevation of S-adenosylhomocysteine in cystathionine beta-synthase-deficient mice.

Dayal S, Bottiglieri T, Arning E, Maeda N, Malinow MR, Sigmund CD, Heistad DD, Faraci FM, Lentz SR.

Circ Res. 2001 Jun 8;88(11):1203-9.

PMID:
11397788
[PubMed - indexed for MEDLINE]
Free Article
8.

Structure of cerebral arterioles in cystathionine beta-synthase-deficient mice.

Baumbach GL, Sigmund CD, Bottiglieri T, Lentz SR.

Circ Res. 2002 Nov 15;91(10):931-7.

PMID:
12433838
[PubMed - indexed for MEDLINE]
Free Article
9.

Abnormal lipid metabolism in cystathionine beta-synthase-deficient mice, an animal model for hyperhomocysteinemia.

Namekata K, Enokido Y, Ishii I, Nagai Y, Harada T, Kimura H.

J Biol Chem. 2004 Dec 17;279(51):52961-9. Epub 2004 Oct 4.

PMID:
15466479
[PubMed - indexed for MEDLINE]
Free Article
10.

Paradoxical absence of a prothrombotic phenotype in a mouse model of severe hyperhomocysteinemia.

Dayal S, Chauhan AK, Jensen M, Leo L, Lynch CM, Faraci FM, Kruger WD, Lentz SR.

Blood. 2012 Mar 29;119(13):3176-83. doi: 10.1182/blood-2011-09-380568. Epub 2011 Dec 20.

PMID:
22186991
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Endogenous elevation of homocysteine induces retinal neuron death in the cystathionine-beta-synthase mutant mouse.

Ganapathy PS, Moister B, Roon P, Mysona BA, Duplantier J, Dun Y, Moister TK, Farley MJ, Prasad PD, Liu K, Smith SB.

Invest Ophthalmol Vis Sci. 2009 Sep;50(9):4460-70. doi: 10.1167/iovs.09-3402. Epub 2009 Apr 8.

PMID:
19357353
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Alterations of retinal vasculature in cystathionine-Beta-synthase mutant mice, a model of hyperhomocysteinemia.

Tawfik A, Al-Shabrawey M, Roon P, Sonne S, Covar JA, Matragoon S, Ganapathy PS, Atherton SS, El-Remessy A, Ganapathy V, Smith SB.

Invest Ophthalmol Vis Sci. 2013 Feb 1;54(2):939-49. doi: 10.1167/iovs.12-10536.

PMID:
23307965
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Modulation of cystathionine beta-synthase level regulates total serum homocysteine in mice.

Wang L, Jhee KH, Hua X, DiBello PM, Jacobsen DW, Kruger WD.

Circ Res. 2004 May 28;94(10):1318-24. Epub 2004 Apr 22.

PMID:
15105297
[PubMed - indexed for MEDLINE]
Free Article
14.

Cystathionine beta synthase deficiency promotes oxidative stress, fibrosis, and steatosis in mice liver.

Robert K, Nehmé J, Bourdon E, Pivert G, Friguet B, Delcayre C, Delabar JM, Janel N.

Gastroenterology. 2005 May;128(5):1405-15.

PMID:
15887121
[PubMed - indexed for MEDLINE]
15.

Cystathionine beta synthase deficiency affects mouse endochondral ossification.

Robert K, Maurin N, Vayssettes C, Siauve N, Janel N.

Anat Rec A Discov Mol Cell Evol Biol. 2005 Jan;282(1):1-7.

PMID:
15622513
[PubMed - indexed for MEDLINE]
Free Article
16.

The neuronal SAPK/JNK pathway is altered in a murine model of hyperhomocysteinemia.

Robert K, Santiard-Baron D, Chassé JF, Paly E, Aupetit J, Kamoun P, London J, Janel N.

J Neurochem. 2004 Apr;89(1):33-43.

PMID:
15030387
[PubMed - indexed for MEDLINE]
17.

Hyperkeratosis in cystathionine beta synthase-deficient mice: an animal model of hyperhomocysteinemia.

Robert K, Maurin N, Ledru A, Delabar J, Janel N.

Anat Rec A Discov Mol Cell Evol Biol. 2004 Oct;280(2):1072-6.

PMID:
15386278
[PubMed - indexed for MEDLINE]
Free Article
18.

Intermediate and severe hyperhomocysteinemia with thrombosis: a study of genetic determinants.

Gaustadnes M, Rüdiger N, Rasmussen K, Ingerslev J.

Thromb Haemost. 2000 Apr;83(4):554-8.

PMID:
10780316
[PubMed - indexed for MEDLINE]
19.

Effects of betaine in a murine model of mild cystathionine-beta-synthase deficiency.

Schwahn BC, Wendel U, Lussier-Cacan S, Mar MH, Zeisel SH, Leclerc D, Castro C, Garrow TA, Rozen R.

Metabolism. 2004 May;53(5):594-9.

PMID:
15131763
[PubMed - indexed for MEDLINE]
20.

Hyperhomocysteinemia accelerates atherosclerosis in cystathionine beta-synthase and apolipoprotein E double knock-out mice with and without dietary perturbation.

Wang H, Jiang X, Yang F, Gaubatz JW, Ma L, Magera MJ, Yang X, Berger PB, Durante W, Pownall HJ, Schafer AI.

Blood. 2003 May 15;101(10):3901-7. Epub 2002 Dec 27.

PMID:
12506016
[PubMed - indexed for MEDLINE]
Free Article
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