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Items: 1 to 20 of 68

1.

Meta-analysis of genome-wide association study data identifies additional type 1 diabetes risk loci.

Cooper JD, Smyth DJ, Smiles AM, Plagnol V, Walker NM, Allen JE, Downes K, Barrett JC, Healy BC, Mychaleckyj JC, Warram JH, Todd JA.

Nat Genet. 2008 Dec;40(12):1399-401. doi: 10.1038/ng.249. Epub 2008 Nov 2.

2.

Follow-up analysis of genome-wide association data identifies novel loci for type 1 diabetes.

Grant SF, Qu HQ, Bradfield JP, Marchand L, Kim CE, Glessner JT, Grabs R, Taback SP, Frackelton EC, Eckert AW, Annaiah K, Lawson ML, Otieno FG, Santa E, Shaner JL, Smith RM, Skraban R, Imielinski M, Chiavacci RM, Grundmeier RW, Stanley CA, Kirsch SE, Waggott D, Paterson AD, Monos DS; DCCT/EDIC Research Group, Polychronakos C, Hakonarson H.

Diabetes. 2009 Jan;58(1):290-5. doi: 10.2337/db08-1022. Epub 2008 Oct 7.

3.

Study of polymorphisms in 4q27, 10p15, and 22q13 regions in autoantibodies stratified type 1 diabetes patients.

Espino-Paisán L, De La Calle H, Fernández-Arquero M, Figueredo MA, De La Concha EG, Urcelay E, Santiago JL.

Autoimmunity. 2011 Dec;44(8):624-30. doi: 10.3109/08916934.2011.592515. Epub 2011 Aug 30.

PMID:
21875375
4.

Robust associations of four new chromosome regions from genome-wide analyses of type 1 diabetes.

Todd JA, Walker NM, Cooper JD, Smyth DJ, Downes K, Plagnol V, Bailey R, Nejentsev S, Field SF, Payne F, Lowe CE, Szeszko JS, Hafler JP, Zeitels L, Yang JH, Vella A, Nutland S, Stevens HE, Schuilenburg H, Coleman G, Maisuria M, Meadows W, Smink LJ, Healy B, Burren OS, Lam AA, Ovington NR, Allen J, Adlem E, Leung HT, Wallace C, Howson JM, Guja C, Ionescu-Tîrgovişte C; Genetics of Type 1 Diabetes in Finland, Simmonds MJ, Heward JM, Gough SC; Wellcome Trust Case Control Consortium, Dunger DB, Wicker LS, Clayton DG.

Nat Genet. 2007 Jul;39(7):857-64. Epub 2007 Jun 6.

5.

Genome-wide association analysis of autoantibody positivity in type 1 diabetes cases.

Plagnol V, Howson JM, Smyth DJ, Walker N, Hafler JP, Wallace C, Stevens H, Jackson L, Simmonds MJ; Type 1 Diabetes Genetics Consortium, Bingley PJ, Gough SC, Todd JA.

PLoS Genet. 2011 Aug;7(8):e1002216. doi: 10.1371/journal.pgen.1002216. Epub 2011 Aug 4.

6.

A genome-wide meta-analysis of six type 1 diabetes cohorts identifies multiple associated loci.

Bradfield JP, Qu HQ, Wang K, Zhang H, Sleiman PM, Kim CE, Mentch FD, Qiu H, Glessner JT, Thomas KA, Frackelton EC, Chiavacci RM, Imielinski M, Monos DS, Pandey R, Bakay M, Grant SF, Polychronakos C, Hakonarson H.

PLoS Genet. 2011 Sep;7(9):e1002293. doi: 10.1371/journal.pgen.1002293. Epub 2011 Sep 29.

7.

Association between type 1 diabetes and GWAS SNPs in the southeast US Caucasian population.

Reddy MV, Wang H, Liu S, Bode B, Reed JC, Steed RD, Anderson SW, Steed L, Hopkins D, She JX.

Genes Immun. 2011 Apr;12(3):208-12. doi: 10.1038/gene.2010.70. Epub 2011 Jan 27.

8.

Follow-up of 1715 SNPs from the Wellcome Trust Case Control Consortium genome-wide association study in type I diabetes families.

Cooper JD, Walker NM, Smyth DJ, Downes K, Healy BC, Todd JA; Type I Diabetes Genetics Consortium.

Genes Immun. 2009 Dec;10 Suppl 1:S85-94. doi: 10.1038/gene.2009.97.

9.

In silico replication of the genome-wide association results of the Type 1 Diabetes Genetics Consortium.

Qu HQ, Bradfield JP, Li Q, Kim C, Frackelton E, Grant SF, Hakonarson H, Polychronakos C.

Hum Mol Genet. 2010 Jun 15;19(12):2534-8. doi: 10.1093/hmg/ddq133. Epub 2010 Apr 8.

10.

Only one independent genetic association with rheumatoid arthritis within the KIAA1109-TENR-IL2-IL21 locus in Caucasian sample sets: confirmation of association of rs6822844 with rheumatoid arthritis at a genome-wide level of significance.

Hollis-Moffatt JE, Chen-Xu M, Topless R, Dalbeth N, Gow PJ, Harrison AA, Highton J, Jones PB, Nissen M, Smith MD, van Rij A, Jones GT, Stamp LK, Merriman TR.

Arthritis Res Ther. 2010;12(3):R116. doi: 10.1186/ar3053. Epub 2010 Jun 16.

11.

Genetic link of type 1 diabetes susceptibility loci with rheumatoid arthritis in Pakistani patients.

Kiani AK, Jahangir S, John P, Bhatti A, Zia A, Wang X, Demirci FY, Kamboh MI.

Immunogenetics. 2015 Jun;67(5-6):277-82. doi: 10.1007/s00251-015-0839-0. Epub 2015 Apr 24. Erratum in: Immunogenetics. 2015 Aug;67(8):477. Jahngir, Sidrah [corrected to Jahangir, Sidrah].

PMID:
25904084
12.

SNP in the genome-wide association study hotspot on chromosome 9p21 confers susceptibility to diabetic nephropathy in type 1 diabetes.

Fagerholm E, Ahlqvist E, Forsblom C, Sandholm N, Syreeni A, Parkkonen M, McKnight AJ, Tarnow L, Maxwell AP, Parving HH, Groop L, Groop PH; FinnDiane Study Group.

Diabetologia. 2012 Sep;55(9):2386-93. Epub 2012 May 29.

PMID:
22643932
13.

Replication study for the association between four Loci identified by a genome-wide association study on European American subjects with type 1 diabetes and susceptibility to diabetic nephropathy in Japanese subjects with type 2 diabetes.

Maeda S, Araki S, Babazono T, Toyoda M, Umezono T, Kawai K, Imanishi M, Uzu T, Watada H, Suzuki D, Kashiwagi A, Iwamoto Y, Kaku K, Kawamori R, Nakamura Y.

Diabetes. 2010 Aug;59(8):2075-9. doi: 10.2337/db10-0067. Epub 2010 May 11.

14.

Caucasian and Asian specific rheumatoid arthritis risk loci reveal limited replication and apparent allelic heterogeneity in north Indians.

Prasad P, Kumar A, Gupta R, Juyal RC, Thelma BK.

PLoS One. 2012;7(2):e31584. doi: 10.1371/journal.pone.0031584. Epub 2012 Feb 15.

15.

Genome-wide association study and meta-analysis find that over 40 loci affect risk of type 1 diabetes.

Barrett JC, Clayton DG, Concannon P, Akolkar B, Cooper JD, Erlich HA, Julier C, Morahan G, Nerup J, Nierras C, Plagnol V, Pociot F, Schuilenburg H, Smyth DJ, Stevens H, Todd JA, Walker NM, Rich SS; Type 1 Diabetes Genetics Consortium.

Nat Genet. 2009 Jun;41(6):703-7. doi: 10.1038/ng.381. Epub 2009 May 10.

16.

Evidence of association with type 1 diabetes in the SLC11A1 gene region.

Yang JH, Downes K, Howson JM, Nutland S, Stevens HE, Walker NM, Todd JA.

BMC Med Genet. 2011 Apr 27;12:59. doi: 10.1186/1471-2350-12-59.

17.

Genome-wide association studies in type 1 diabetes.

Grant SF, Hakonarson H.

Curr Diab Rep. 2009 Apr;9(2):157-63. Review.

PMID:
19323961
18.

Novel genetic risk markers for ulcerative colitis in the IL2/IL21 region are in epistasis with IL23R and suggest a common genetic background for ulcerative colitis and celiac disease.

Glas J, Stallhofer J, Ripke S, Wetzke M, Pfennig S, Klein W, Epplen JT, Griga T, Schiemann U, Lacher M, Koletzko S, Folwaczny M, Lohse P, Göke B, Ochsenkühn T, Müller-Myhsok B, Brand S.

Am J Gastroenterol. 2009 Jul;104(7):1737-44. doi: 10.1038/ajg.2009.163. Epub 2009 May 19.

PMID:
19455118
19.

Novel association in chromosome 4q27 region with rheumatoid arthritis and confirmation of type 1 diabetes point to a general risk locus for autoimmune diseases.

Zhernakova A, Alizadeh BZ, Bevova M, van Leeuwen MA, Coenen MJ, Franke B, Franke L, Posthumus MD, van Heel DA, van der Steege G, Radstake TR, Barrera P, Roep BO, Koeleman BP, Wijmenga C.

Am J Hum Genet. 2007 Dec;81(6):1284-8. Epub 2007 Oct 24.

20.

A single nucleotide polymorphism within DUSP9 is associated with susceptibility to type 2 diabetes in a Japanese population.

Fukuda H, Imamura M, Tanaka Y, Iwata M, Hirose H, Kaku K, Maegawa H, Watada H, Tobe K, Kashiwagi A, Kawamori R, Maeda S.

PLoS One. 2012;7(9):e46263. doi: 10.1371/journal.pone.0046263. Epub 2012 Sep 27.

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