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Items: 1 to 20 of 110

1.

Sarcolemma-localized nNOS is required to maintain activity after mild exercise.

Kobayashi YM, Rader EP, Crawford RW, Iyengar NK, Thedens DR, Faulkner JA, Parikh SV, Weiss RM, Chamberlain JS, Moore SA, Campbell KP.

Nature. 2008 Nov 27;456(7221):511-5. doi: 10.1038/nature07414. Epub 2008 Oct 26.

2.

Fatigue and muscle atrophy in a mouse model of myasthenia gravis is paralleled by loss of sarcolemmal nNOS.

Meinen S, Lin S, Rüegg MA, Punga AR.

PLoS One. 2012;7(8):e44148. doi: 10.1371/journal.pone.0044148. Epub 2012 Aug 28.

3.

Golgi and sarcolemmal neuronal NOS differentially regulate contraction-induced fatigue and vasoconstriction in exercising mouse skeletal muscle.

Percival JM, Anderson KN, Huang P, Adams ME, Froehner SC.

J Clin Invest. 2010 Mar;120(3):816-26. doi: 10.1172/JCI40736.

4.

NO more muscle fatigue.

Heydemann A, McNally E.

J Clin Invest. 2009 Mar;119(3):448-50.

5.

Dystrophins carrying spectrin-like repeats 16 and 17 anchor nNOS to the sarcolemma and enhance exercise performance in a mouse model of muscular dystrophy.

Lai Y, Thomas GD, Yue Y, Yang HT, Li D, Long C, Judge L, Bostick B, Chamberlain JS, Terjung RL, Duan D.

J Clin Invest. 2009 Mar;119(3):624-35. doi: 10.1172/JCI36612. Epub 2009 Feb 23.

6.

Functional deficits in nNOSmu-deficient skeletal muscle: myopathy in nNOS knockout mice.

Percival JM, Anderson KN, Gregorevic P, Chamberlain JS, Froehner SC.

PLoS One. 2008;3(10):e3387. doi: 10.1371/journal.pone.0003387. Epub 2008 Oct 13.

7.

Vasomodulation by skeletal muscle-derived nitric oxide requires alpha-syntrophin-mediated sarcolemmal localization of neuronal Nitric oxide synthase.

Thomas GD, Shaul PW, Yuhanna IS, Froehner SC, Adams ME.

Circ Res. 2003 Mar 21;92(5):554-60. Epub 2003 Feb 13.

8.

Sarcolemmal nNOS anchoring reveals a qualitative difference between dystrophin and utrophin.

Li D, Bareja A, Judge L, Yue Y, Lai Y, Fairclough R, Davies KE, Chamberlain JS, Duan D.

J Cell Sci. 2010 Jun 15;123(Pt 12):2008-13. doi: 10.1242/jcs.064808. Epub 2010 May 18.

9.
10.

Evaluation of the therapeutic utility of phosphodiesterase 5A inhibition in the mdx mouse model of duchenne muscular dystrophy.

Percival JM, Adamo CM, Beavo JA, Froehner SC.

Handb Exp Pharmacol. 2011;(204):323-44. doi: 10.1007/978-3-642-17969-3_14.

11.

Early functional muscle regeneration after myotoxic injury in mice is unaffected by nNOS absence.

Church JE, Gehrig SM, Chee A, Naim T, Trieu J, McConell GK, Lynch GS.

Am J Physiol Regul Integr Comp Physiol. 2011 Nov;301(5):R1358-66. doi: 10.1152/ajpregu.00096.2011. Epub 2011 Aug 17.

12.

Loss of nNOS inhibits compensatory muscle hypertrophy and exacerbates inflammation and eccentric contraction-induced damage in mdx mice.

Froehner SC, Reed SM, Anderson KN, Huang PL, Percival JM.

Hum Mol Genet. 2015 Jan 15;24(2):492-505. doi: 10.1093/hmg/ddu469. Epub 2014 Sep 11.

13.

alpha1-syntrophin gene disruption results in the absence of neuronal-type nitric-oxide synthase at the sarcolemma but does not induce muscle degeneration.

Kameya S, Miyagoe Y, Nonaka I, Ikemoto T, Endo M, Hanaoka K, Nabeshima Y, Takeda S.

J Biol Chem. 1999 Jan 22;274(4):2193-200.

14.

Sarcolemmal neuronal nitric oxide synthase defect in limb-girdle muscular dystrophy: an adverse modulating factor in the disease course?

Fanin M, Tasca E, Nascimbeni AC, Angelini C.

J Neuropathol Exp Neurol. 2009 Apr;68(4):383-90. doi: 10.1097/NEN.0b013e31819cd612.

15.

Loss of sarcolemmal nNOS is common in acquired and inherited neuromuscular disorders.

Finanger Hedderick EL, Simmers JL, Soleimani A, Andres-Mateos E, Marx R, Files DC, King L, Crawford TO, Corse AM, Cohn RD.

Neurology. 2011 Mar 15;76(11):960-7. doi: 10.1212/WNL.0b013e31821043c8.

16.

Dual AAV therapy ameliorates exercise-induced muscle injury and functional ischemia in murine models of Duchenne muscular dystrophy.

Zhang Y, Yue Y, Li L, Hakim CH, Zhang K, Thomas GD, Duan D.

Hum Mol Genet. 2013 Sep 15;22(18):3720-9. doi: 10.1093/hmg/ddt224. Epub 2013 May 15.

17.

Muscular dystrophy in mdx mice despite lack of neuronal nitric oxide synthase.

Chao DS, Silvagno F, Bredt DS.

J Neurochem. 1998 Aug;71(2):784-9.

18.

NO production results in suspension-induced muscle atrophy through dislocation of neuronal NOS.

Suzuki N, Motohashi N, Uezumi A, Fukada S, Yoshimura T, Itoyama Y, Aoki M, Miyagoe-Suzuki Y, Takeda S.

J Clin Invest. 2007 Sep;117(9):2468-76.

19.
20.

The beta-isoform of neuronal nitric oxide synthase (nNOS) lacking the PDZ domain is localized at the sarcolemma.

Baum O, Schläppi S, Huber-Abel FA, Weichert A, Hoppeler H, Zakrzewicz A.

FEBS Lett. 2011 Oct 20;585(20):3219-23. doi: 10.1016/j.febslet.2011.09.016. Epub 2011 Sep 19.

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