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Items: 1 to 20 of 153


A new recombinant bacille Calmette-Guérin vaccine safely induces significantly enhanced tuberculosis-specific immunity in human volunteers.

Hoft DF, Blazevic A, Abate G, Hanekom WA, Kaplan G, Soler JH, Weichold F, Geiter L, Sadoff JC, Horwitz MA.

J Infect Dis. 2008 Nov 15;198(10):1491-501. doi: 10.1086/592450.


Efficacy of recombinant bacille Calmette-Guérin vaccine secreting interleukin-15/antigen 85B fusion protein in providing protection against Mycobacterium tuberculosis.

Tang C, Yamada H, Shibata K, Maeda N, Yoshida S, Wajjwalku W, Ohara N, Yamada T, Kinoshita T, Yoshikai Y.

J Infect Dis. 2008 May 1;197(9):1263-74. doi: 10.1086/586902.


Recombinant BCG coexpressing Ag85B, ESAT-6 and Rv3620c elicits specific Th1 immune responses in C57BL/6 mice.

Yang E, Lu Y, Xu Y, Liang Q, Wang C, Wang H, Shen H.

Microb Pathog. 2014 Apr-May;69-70:53-9. doi: 10.1016/j.micpath.2014.03.011. Epub 2014 Apr 12.


Evaluation of a new recombinant BCG which contains mycobacterial antigen ag85B-mpt64(190-198)-mtb8.4 in C57/BL6 mice.

Qie YQ, Wang JL, Zhu BD, Xu Y, Wang QZ, Chen JZ, Wang HH.

Scand J Immunol. 2008 Feb;67(2):133-9. doi: 10.1111/j.1365-3083.2007.02048.x.


More vaccine efficacy studies on the recombinant Bacille Calmette-Guerin co-expressing Ag85B, Mpt64 and Mtb8.4.

Qie YQ, Wang JL, Liu W, Shen H, Chen JZ, Zhu BD, Xu Y, Zhang XL, Wang HH.

Scand J Immunol. 2009 Apr;69(4):342-50. doi: 10.1111/j.1365-3083.2009.02231.x.


Novel recombinant BCG coexpressing Ag85B, ESAT-6 and Rv2608 elicits significantly enhanced cellular immune and antibody responses in C57BL/6 mice.

Lu Y, Xu Y, Yang E, Wang C, Wang H, Shen H.

Scand J Immunol. 2012 Sep;76(3):271-7. doi: 10.1111/j.1365-3083.2012.02726.x.


Recombinant BCG coexpressing Ag85B, ESAT-6 and mouse-IFN-gamma confers effective protection against Mycobacterium tuberculosis in C57BL/6 mice.

Xu Y, Zhu B, Wang Q, Chen J, Qie Y, Wang J, Wang H, Wang B, Wang H.

FEMS Immunol Med Microbiol. 2007 Dec;51(3):480-7. Epub 2007 Oct 4.


rBCG induces strong antigen-specific T cell responses in rhesus macaques in a prime-boost setting with an adenovirus 35 tuberculosis vaccine vector.

Magalhaes I, Sizemore DR, Ahmed RK, Mueller S, Wehlin L, Scanga C, Weichold F, Schirru G, Pau MG, Goudsmit J, Kühlmann-Berenzon S, Spångberg M, Andersson J, Gaines H, Thorstensson R, Skeiky YA, Sadoff J, Maeurer M.

PLoS One. 2008;3(11):e3790. doi: 10.1371/journal.pone.0003790. Epub 2008 Nov 21.


Immunogenicity and protective efficacy of a novel recombinant BCG strain overexpressing antigens Ag85A and Ag85B.

Wang C, Fu R, Chen Z, Tan K, Chen L, Teng X, Lu J, Shi C, Fan X.

Clin Dev Immunol. 2012;2012:563838. doi: 10.1155/2012/563838. Epub 2012 Apr 18.


A novel recombinant BCG-expressing pro-apoptotic protein BAX enhances Th1 protective immune responses in mice.

Li G, Liu G, Song N, Kong C, Huang Q, Su H, Bi A, Luo L, Zhu L, Xu Y, Wang H.

Mol Immunol. 2015 Aug;66(2):346-56. doi: 10.1016/j.molimm.2015.04.003. Epub 2015 May 18.


Evaluation of protective efficacy conferred by a recombinant Mycobacterium bovis BCG expressing a fusion protein of Ag85A-ESAT-6.

Deng YH, He HY, Zhang BS.

J Microbiol Immunol Infect. 2014 Feb;47(1):48-56. doi: 10.1016/j.jmii.2012.11.005. Epub 2013 Jan 26.


Dose of incorporated immunodominant antigen in recombinant BCG impacts modestly on Th1 immune response and protective efficiency against Mycobacterium tuberculosis in mice.

Ma H, Wu K, Liu F, Yang H, Kang H, Chen NN, Yuan Q, Zhou WJ, Fan XY.

J Immunol Res. 2014;2014:196124. doi: 10.1155/2014/196124. Epub 2014 Jul 23.


Extraordinarily few organisms of a live recombinant BCG vaccine against tuberculosis induce maximal cell-mediated and protective immunity.

Horwitz MA, Harth G, Dillon BJ, Maslesa-Galić S.

Vaccine. 2006 Jan 23;24(4):443-51. Epub 2005 Aug 11.


Enhanced and durable protective immune responses induced by a cocktail of recombinant BCG strains expressing antigens of multistage of Mycobacterium tuberculosis.

Liang J, Teng X, Yuan X, Zhang Y, Shi C, Yue T, Zhou L, Li J, Fan X.

Mol Immunol. 2015 Aug;66(2):392-401. doi: 10.1016/j.molimm.2015.04.017. Epub 2015 May 18.


Immunogenicity of recombinant Mycobacterium bovis bacille Calmette-Guèrin clones expressing T and B cell epitopes of Mycobacterium tuberculosis antigens.

Mohamud R, Azlan M, Yero D, Alvarez N, Sarmiento ME, Acosta A, Norazmi MN.

BMC Immunol. 2013;14 Suppl 1:S5. doi: 10.1186/1471-2172-14-S1-S5. Epub 2013 Feb 25.


Enhanced protection against tuberculosis by vaccination with recombinant BCG over-expressing HspX protein.

Shi C, Chen L, Chen Z, Zhang Y, Zhou Z, Lu J, Fu R, Wang C, Fang Z, Fan X.

Vaccine. 2010 Jul 19;28(32):5237-44. doi: 10.1016/j.vaccine.2010.05.063. Epub 2010 Jun 9.

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