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Results: 1 to 20 of 189

Similar articles for PubMed (Select 18802479)

1.

CTLs are targeted to kill beta cells in patients with type 1 diabetes through recognition of a glucose-regulated preproinsulin epitope.

Skowera A, Ellis RJ, Varela-Calviño R, Arif S, Huang GC, Van-Krinks C, Zaremba A, Rackham C, Allen JS, Tree TI, Zhao M, Dayan CM, Sewell AK, Unger WW, Drijfhout JW, Ossendorp F, Roep BO, Peakman M.

J Clin Invest. 2008 Oct;118(10):3390-402. doi: 10.1172/JCI35449. Erratum in: J Clin Invest. 2009 Sep;119(9):2844. Unger, Wendy [corrected to Unger, Wendy W].

2.

Circulating preproinsulin signal peptide-specific CD8 T cells restricted by the susceptibility molecule HLA-A24 are expanded at onset of type 1 diabetes and kill β-cells.

Kronenberg D, Knight RR, Estorninho M, Ellis RJ, Kester MG, de Ru A, Eichmann M, Huang GC, Powrie J, Dayan CM, Skowera A, van Veelen PA, Peakman M.

Diabetes. 2012 Jul;61(7):1752-9. doi: 10.2337/db11-1520. Epub 2012 Apr 20.

3.

Discovery of low-affinity preproinsulin epitopes and detection of autoreactive CD8 T-cells using combinatorial MHC multimers.

Unger WW, Velthuis J, Abreu JR, Laban S, Quinten E, Kester MG, Reker-Hadrup S, Bakker AH, Duinkerken G, Mulder A, Franken KL, Hilbrands R, Keymeulen B, Peakman M, Ossendorp F, Drijfhout JW, Schumacher TN, Roep BO.

J Autoimmun. 2011 Nov;37(3):151-9. doi: 10.1016/j.jaut.2011.05.012. Epub 2011 Jun 1.

PMID:
21636247
4.

Autoreactive CD8 T cells associated with beta cell destruction in type 1 diabetes.

Pinkse GG, Tysma OH, Bergen CA, Kester MG, Ossendorp F, van Veelen PA, Keymeulen B, Pipeleers D, Drijfhout JW, Roep BO.

Proc Natl Acad Sci U S A. 2005 Dec 20;102(51):18425-30. Epub 2005 Dec 9.

5.

Recognition of HLA class I-restricted beta-cell epitopes in type 1 diabetes.

Ouyang Q, Standifer NE, Qin H, Gottlieb P, Verchere CB, Nepom GT, Tan R, Panagiotopoulos C.

Diabetes. 2006 Nov;55(11):3068-74.

6.

Human CD8 responses to a complete epitope set from preproinsulin: implications for approaches to epitope discovery.

Baker C, Petrich de Marquesini LG, Bishop AJ, Hedges AJ, Dayan CM, Wong FS.

J Clin Immunol. 2008 Jul;28(4):350-60. doi: 10.1007/s10875-008-9177-4. Epub 2008 Feb 29.

PMID:
18311511
7.

CD8 T cell autoreactivity to preproinsulin epitopes with very low human leucocyte antigen class I binding affinity.

Abreu JR, Martina S, Verrijn Stuart AA, Fillié YE, Franken KL, Drijfhout JW, Roep BO.

Clin Exp Immunol. 2012 Oct;170(1):57-65. doi: 10.1111/j.1365-2249.2012.04635.x.

8.

The frequency and immunodominance of islet-specific CD8+ T-cell responses change after type 1 diabetes diagnosis and treatment.

Martinuzzi E, Novelli G, Scotto M, Blancou P, Bach JM, Chaillous L, Bruno G, Chatenoud L, van Endert P, Mallone R.

Diabetes. 2008 May;57(5):1312-20. doi: 10.2337/db07-1594. Epub 2008 Feb 27.

9.

Pro- and anti-inflammatory cytokine production by autoimmune T cells against preproinsulin in HLA-DRB1*04, DQ8 Type 1 diabetes.

Durinovic-Belló I, Schlosser M, Riedl M, Maisel N, Rosinger S, Kalbacher H, Deeg M, Ziegler M, Elliott J, Roep BO, Karges W, Boehm BO.

Diabetologia. 2004 Mar;47(3):439-50. Epub 2004 Jan 24.

PMID:
14745491
10.

Processing in the endoplasmic reticulum generates an epitope on the insulin A chain that stimulates diabetogenic CD8 T cell responses.

Brosi H, Reiser M, Rajasalu T, Spyrantis A, Oswald F, Boehm BO, Schirmbeck R.

J Immunol. 2009 Dec 1;183(11):7187-95. doi: 10.4049/jimmunol.0901573. Epub 2009 Nov 4.

11.

Immunology of Diabetes Society T-Cell Workshop: HLA class I tetramer-directed epitope validation initiative T-Cell Workshop Report-HLA Class I Tetramer Validation Initiative.

Mallone R, Scotto M, Janicki CN, James EA, Fitzgerald-Miller L, Wagner R, Gottlieb P, Thorpe J, Jospe N, Durinovic-Bellò I, Boitard C, Lou O, Dayan CM, Wong FS; T-Cell Workshop Committee, Immunology of Diabetes Society.

Diabetes Metab Res Rev. 2011 Nov;27(8):720-6. doi: 10.1002/dmrr.1243.

PMID:
22069251
12.

The role of low avidity T cells in the protection against type 1 diabetes: a modeling investigation.

Khadra A, Santamaria P, Edelstein-Keshet L.

J Theor Biol. 2009 Jan 7;256(1):126-41. doi: 10.1016/j.jtbi.2008.09.019. Epub 2008 Oct 6.

PMID:
18950644
13.

HLA class I epitope discovery in type 1 diabetes.

van Endert P, Hassainya Y, Lindo V, Bach JM, Blancou P, Lemonnier F, Mallone R.

Ann N Y Acad Sci. 2006 Oct;1079:190-7.

PMID:
17130554
14.

Human β-cell killing by autoreactive preproinsulin-specific CD8 T cells is predominantly granule-mediated with the potency dependent upon T-cell receptor avidity.

Knight RR, Kronenberg D, Zhao M, Huang GC, Eichmann M, Bulek A, Wooldridge L, Cole DK, Sewell AK, Peakman M, Skowera A.

Diabetes. 2013 Jan;62(1):205-13. doi: 10.2337/db12-0315. Epub 2012 Aug 30.

15.

Novel epitope begets a novel pathway in type 1 diabetes progression.

Frelinger JA.

J Clin Invest. 2008 Oct;118(10):3268-71. doi: 10.1172/JCI37125.

16.

CD8+ T-cell responses identify beta-cell autoimmunity in human type 1 diabetes.

Mallone R, Martinuzzi E, Blancou P, Novelli G, Afonso G, Dolz M, Bruno G, Chaillous L, Chatenoud L, Bach JM, van Endert P.

Diabetes. 2007 Mar;56(3):613-21.

17.

CD4+ T cells from type 1 diabetic and healthy subjects exhibit different thresholds of activation to a naturally processed proinsulin epitope.

Yang J, Danke N, Roti M, Huston L, Greenbaum C, Pihoker C, James E, Kwok WW.

J Autoimmun. 2008 Aug;31(1):30-41. doi: 10.1016/j.jaut.2008.02.001. Epub 2008 Apr 2.

PMID:
18385016
18.

The diabetogenic, insulin-specific CD8 T cell response primed in the experimental autoimmune diabetes model in RIP-B7.1 mice.

Karges W, Rajasalu T, Spyrantis A, Wieland A, Boehm B, Schirmbeck R.

Eur J Immunol. 2007 Aug;37(8):2097-103.

PMID:
17615584
19.

T cell recognition of autoantigens in human type 1 diabetes: clinical perspectives.

Mallone R, Brezar V, Boitard C.

Clin Dev Immunol. 2011;2011:513210. doi: 10.1155/2011/513210. Epub 2011 Jul 19. Review.

20.

Promiscuous binding of proinsulin peptides to Type 1 diabetes-permissive and -protective HLA class II molecules.

Astill TP, Ellis RJ, Arif S, Tree TI, Peakman M.

Diabetologia. 2003 Apr;46(4):496-503. Epub 2003 Apr 9.

PMID:
12684749
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