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Results: 1 to 20 of 110

1.

UBXD7 binds multiple ubiquitin ligases and implicates p97 in HIF1alpha turnover.

Alexandru G, Graumann J, Smith GT, Kolawa NJ, Fang R, Deshaies RJ.

Cell. 2008 Sep 5;134(5):804-16. doi: 10.1016/j.cell.2008.06.048.

PMID:
18775313
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

UBXN7 docks on neddylated cullin complexes using its UIM motif and causes HIF1α accumulation.

Bandau S, Knebel A, Gage ZO, Wood NT, Alexandru G.

BMC Biol. 2012 Apr 26;10:36. doi: 10.1186/1741-7007-10-36.

PMID:
22537386
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

NEDD8 links cullin-RING ubiquitin ligase function to the p97 pathway.

den Besten W, Verma R, Kleiger G, Oania RS, Deshaies RJ.

Nat Struct Mol Biol. 2012 Apr 1;19(5):511-6, S1. doi: 10.1038/nsmb.2269.

PMID:
22466964
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

UBXD1 binds p97 through two independent binding sites.

Kern M, Fernandez-Sáiz V, Schäfer Z, Buchberger A.

Biochem Biophys Res Commun. 2009 Mar 6;380(2):303-7. doi: 10.1016/j.bbrc.2009.01.076. Epub 2009 Jan 25.

PMID:
19174149
[PubMed - indexed for MEDLINE]
5.

The structural and functional basis of the p97/valosin-containing protein (VCP)-interacting motif (VIM): mutually exclusive binding of cofactors to the N-terminal domain of p97.

Hänzelmann P, Schindelin H.

J Biol Chem. 2011 Nov 4;286(44):38679-90. doi: 10.1074/jbc.M111.274506. Epub 2011 Sep 13.

PMID:
21914798
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

AAA ATPase p97/valosin-containing protein interacts with gp78, a ubiquitin ligase for endoplasmic reticulum-associated degradation.

Zhong X, Shen Y, Ballar P, Apostolou A, Agami R, Fang S.

J Biol Chem. 2004 Oct 29;279(44):45676-84. Epub 2004 Aug 24.

PMID:
15331598
[PubMed - indexed for MEDLINE]
Free Article
7.

The UBX protein SAKS1 negatively regulates endoplasmic reticulum-associated degradation and p97-dependent degradation.

LaLonde DP, Bretscher A.

J Biol Chem. 2011 Feb 11;286(6):4892-901. doi: 10.1074/jbc.M110.158030. Epub 2010 Dec 6.

PMID:
21135095
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Hierarchical binding of cofactors to the AAA ATPase p97.

Hänzelmann P, Buchberger A, Schindelin H.

Structure. 2011 Jun 8;19(6):833-43. doi: 10.1016/j.str.2011.03.018.

PMID:
21645854
[PubMed - indexed for MEDLINE]
Free Article
9.

The ubiquitin regulatory X (UBX) domain-containing protein TUG regulates the p97 ATPase and resides at the endoplasmic reticulum-golgi intermediate compartment.

Orme CM, Bogan JS.

J Biol Chem. 2012 Feb 24;287(9):6679-92. doi: 10.1074/jbc.M111.284232. Epub 2011 Dec 29.

PMID:
22207755
[PubMed - indexed for MEDLINE]
Free PMC Article
10.
11.

Cdc48p is UBX-linked to ER ubiquitin ligases.

Römisch K.

Trends Biochem Sci. 2006 Jan;31(1):24-5. Epub 2005 Nov 28. Review.

PMID:
16316751
[PubMed - indexed for MEDLINE]
12.

The tissue-specific Rep8/UBXD6 tethers p97 to the endoplasmic reticulum membrane for degradation of misfolded proteins.

Madsen L, Kriegenburg F, Vala A, Best D, Prag S, Hofmann K, Seeger M, Adams IR, Hartmann-Petersen R.

PLoS One. 2011;6(9):e25061. doi: 10.1371/journal.pone.0025061. Epub 2011 Sep 15.

PMID:
21949850
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Regulation of p97 in the ubiquitin-proteasome system by the UBX protein-family.

Kloppsteck P, Ewens CA, Förster A, Zhang X, Freemont PS.

Biochim Biophys Acta. 2012 Jan;1823(1):125-9. doi: 10.1016/j.bbamcr.2011.09.006. Epub 2011 Sep 22. Review.

PMID:
21963883
[PubMed - indexed for MEDLINE]
Free Article
14.

UBX domain proteins: major regulators of the AAA ATPase Cdc48/p97.

Schuberth C, Buchberger A.

Cell Mol Life Sci. 2008 Aug;65(15):2360-71. doi: 10.1007/s00018-008-8072-8. Review.

PMID:
18438607
[PubMed - indexed for MEDLINE]
15.

Insights into adaptor binding to the AAA protein p97.

Yeung HO, Kloppsteck P, Niwa H, Isaacson RL, Matthews S, Zhang X, Freemont PS.

Biochem Soc Trans. 2008 Feb;36(Pt 1):62-7. doi: 10.1042/BST0360062. Review.

PMID:
18208387
[PubMed - indexed for MEDLINE]
16.

VHL-box and SOCS-box domains determine binding specificity for Cul2-Rbx1 and Cul5-Rbx2 modules of ubiquitin ligases.

Kamura T, Maenaka K, Kotoshiba S, Matsumoto M, Kohda D, Conaway RC, Conaway JW, Nakayama KI.

Genes Dev. 2004 Dec 15;18(24):3055-65.

PMID:
15601820
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Ubx2 links the Cdc48 complex to ER-associated protein degradation.

Neuber O, Jarosch E, Volkwein C, Walter J, Sommer T.

Nat Cell Biol. 2005 Oct;7(10):993-8. Epub 2005 Sep 18.

PMID:
16179953
[PubMed - indexed for MEDLINE]
Free Article
18.

Structural and mechanistic insights into the arginine/lysine-rich peptide motifs that interact with P97/VCP.

Liu S, Fu QS, Zhao J, Hu HY.

Biochim Biophys Acta. 2013 Dec;1834(12):2672-8. doi: 10.1016/j.bbapap.2013.09.021. Epub 2013 Oct 4.

PMID:
24100225
[PubMed - indexed for MEDLINE]
19.

Mechanisms targeting apolipoprotein B100 to proteasomal degradation: evidence that degradation is initiated by BiP binding at the N terminus and the formation of a p97 complex at the C terminus.

Rutledge AC, Qiu W, Zhang R, Kohen-Avramoglu R, Nemat-Gorgani N, Adeli K.

Arterioscler Thromb Vasc Biol. 2009 Apr;29(4):579-85. doi: 10.1161/ATVBAHA.108.181859. Epub 2009 Jan 22.

PMID:
19164805
[PubMed - indexed for MEDLINE]
Free Article
20.

BTB protein Keap1 targets antioxidant transcription factor Nrf2 for ubiquitination by the Cullin 3-Roc1 ligase.

Furukawa M, Xiong Y.

Mol Cell Biol. 2005 Jan;25(1):162-71.

PMID:
15601839
[PubMed - indexed for MEDLINE]
Free PMC Article

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