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1.

Blood pressure is reduced and insulin sensitivity increased in glucose-intolerant, hypertensive subjects after 15 days of consuming high-polyphenol dark chocolate.

Grassi D, Desideri G, Necozione S, Lippi C, Casale R, Properzi G, Blumberg JB, Ferri C.

J Nutr. 2008 Sep;138(9):1671-6.

2.

Cocoa, glucose tolerance and insulin signalling: the cardiometabolic protection.

Grassi D, Desideri G, Mai F, Martella L, De Feo M, Soddu D, Fellini E, Veneri M, Stamerra CA, Ferri C.

J Agric Food Chem. 2015 Jun 30. [Epub ahead of print]

PMID:
26126077
3.

Cocoa, blood pressure and cardiovascular health.

Ferri C, Desideri G, Ferri L, Proietti I, Di Agostino S, Martella L, Mai F, Di Giosia P, Grassi D.

J Agric Food Chem. 2015 Jun 30. [Epub ahead of print]

PMID:
26125676
4.

Potential implications of dose and diet for the effects of cocoa flavanols on cardio-metabolic function.

Davison K, Howe P.

J Agric Food Chem. 2015 Jun 25. [Epub ahead of print]

PMID:
26111215
5.

5D.07: THE IMPACT OF FLAVONOL-RICH DARK CHOCOLATE ON BLOOD PRESSURE AND VASCULAR FUNCTION IN HEALTHY SUBJECTS.

Heuten H, Van Ackeren K, Hoymans V, Wouters K, Goovaerts I, Conraads V, Vrints C.

J Hypertens. 2015 Jun;33 Suppl 1:e72. doi: 10.1097/01.hjh.0000467546.67897.69.

PMID:
26102915
6.

High-cocoa polyphenol-rich chocolate improves blood pressure in patients with diabetes and hypertension.

Rostami A, Khalili M, Haghighat N, Eghtesadi S, Shidfar F, Heidari I, Ebrahimpour-Koujan S, Eghtesadi M.

ARYA Atheroscler. 2015 Jan;11(1):21-9.

7.

The cardiovascular benefits of dark chocolate.

Kerimi A, Williamson G.

Vascul Pharmacol. 2015 May 27. pii: S1537-1891(15)00113-5. doi: 10.1016/j.vph.2015.05.011. [Epub ahead of print] Review.

PMID:
26026398
8.

Effects of the pure flavonoids epicatechin and quercetin on vascular function and cardiometabolic health: a randomized, double-blind, placebo-controlled, crossover trial.

Dower JI, Geleijnse JM, Gijsbers L, Zock PL, Kromhout D, Hollman PC.

Am J Clin Nutr. 2015 May;101(5):914-21. doi: 10.3945/ajcn.114.098590. Epub 2015 Feb 25.

PMID:
25934864
9.

Effects of high flavanol dark chocolate on cardiovascular function and platelet aggregation.

Rull G, Mohd-Zain ZN, Shiel J, Lundberg MH, Collier DJ, Johnston A, Warner TD, Corder R.

Vascul Pharmacol. 2015 Apr 11. pii: S1537-1891(15)00051-8. doi: 10.1016/j.vph.2015.02.010. [Epub ahead of print]

PMID:
25869509
10.

How effective are current dietary guidelines for cardiovascular disease prevention in healthy middle-aged and older men and women? A randomized controlled trial.

Reidlinger DP, Darzi J, Hall WL, Seed PT, Chowienczyk PJ, Sanders TA; Cardiovascular disease risk REduction Study (CRESSIDA) investigators.

Am J Clin Nutr. 2015 May;101(5):922-30. doi: 10.3945/ajcn.114.097352. Epub 2015 Mar 18.

11.

Adaptation of β-Cell and Endothelial Function to Carbohydrate Loading: Influence of Insulin Resistance.

Hurwitz BE, Schneiderman N, Marks JB, Mendez AJ, Gonzalez A, Llabre MM, Smith SR, Bizzotto R, Santini E, Manca ML, Skyler JS, Mari A, Ferrannini E.

Diabetes. 2015 Jul;64(7):2550-9. doi: 10.2337/db15-0106. Epub 2015 Mar 9.

PMID:
25754957
12.

Cocoa flavanol consumption improves cognitive function, blood pressure control, and metabolic profile in elderly subjects: the Cocoa, Cognition, and Aging (CoCoA) Study--a randomized controlled trial.

Mastroiacovo D, Kwik-Uribe C, Grassi D, Necozione S, Raffaele A, Pistacchio L, Righetti R, Bocale R, Lechiara MC, Marini C, Ferri C, Desideri G.

Am J Clin Nutr. 2015 Mar;101(3):538-48. doi: 10.3945/ajcn.114.092189. Epub 2014 Dec 17.

13.

Interactions between cocoa flavanols and inorganic nitrate: additive effects on endothelial function at achievable dietary amounts.

Rodriguez-Mateos A, Hezel M, Aydin H, Kelm M, Lundberg JO, Weitzberg E, Spencer JP, Heiss C.

Free Radic Biol Med. 2015 Mar;80:121-8. doi: 10.1016/j.freeradbiomed.2014.12.009. Epub 2014 Dec 18.

PMID:
25530151
14.

Predictors of vascular remodelling in hypertensive subjects with well-controlled blood pressure levels.

Puato M, Rattazzi M, Zanon M, Benetti E, Faggin E, Palatini P, Pauletto P.

J Hum Hypertens. 2014 Dec 18. doi: 10.1038/jhh.2014.121. [Epub ahead of print]

PMID:
25518897
15.
16.

Cocoa consumption dose-dependently improves flow-mediated dilation and arterial stiffness decreasing blood pressure in healthy individuals.

Grassi D, Desideri G, Necozione S, di Giosia P, Barnabei R, Allegaert L, Bernaert H, Ferri C.

J Hypertens. 2015 Feb;33(2):294-303. doi: 10.1097/HJH.0000000000000412.

PMID:
25380152
17.

Intake of polyphenol-rich pomegranate pure juice influences urinary glucocorticoids, blood pressure and homeostasis model assessment of insulin resistance in human volunteers.

Tsang C, Smail NF, Almoosawi S, Davidson I, Al-Dujaili EA.

J Nutr Sci. 2012 Aug 31;1:e9. doi: 10.1017/jns.2012.10. eCollection 2012.

18.

The effects of beta-glucan rich oat bread on serum nitric oxide and vascular endothelial function in patients with hypercholesterolemia.

Tabesh F, Sanei H, Jahangiri M, Momenizadeh A, Tabesh E, Pourmohammadi K, Sadeghi M.

Biomed Res Int. 2014;2014:481904. doi: 10.1155/2014/481904. Epub 2014 Jun 12.

19.

Dark chocolate acutely improves walking autonomy in patients with peripheral artery disease.

Loffredo L, Perri L, Catasca E, Pignatelli P, Brancorsini M, Nocella C, De Falco E, Bartimoccia S, Frati G, Carnevale R, Violi F.

J Am Heart Assoc. 2014 Jul 2;3(4). pii: e001072. doi: 10.1161/JAHA.114.001072.

20.

Central arterial hemodynamic effects of dark chocolate ingestion in young healthy people: a randomized and controlled trial.

Pereira T, Maldonado J, Laranjeiro M, Coutinho R, Cardoso E, Andrade I, Conde J.

Cardiol Res Pract. 2014;2014:945951. doi: 10.1155/2014/945951. Epub 2014 May 27.

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