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Items: 1 to 20 of 151


Cloning of genes involved in chromosomal translocations by high-resolution single nucleotide polymorphism genomic microarray.

Kawamata N, Ogawa S, Zimmermann M, Niebuhr B, Stocking C, Sanada M, Hemminki K, Yamatomo G, Nannya Y, Koehler R, Flohr T, Miller CW, Harbott J, Ludwig WD, Stanulla M, Schrappe M, Bartram CR, Koeffler HP.

Proc Natl Acad Sci U S A. 2008 Aug 19;105(33):11921-6. doi: 10.1073/pnas.0711039105. Epub 2008 Aug 12.


Variable breakpoints target PAX5 in patients with dicentric chromosomes: a model for the basis of unbalanced translocations in cancer.

An Q, Wright SL, Konn ZJ, Matheson E, Minto L, Moorman AV, Parker H, Griffiths M, Ross FM, Davies T, Hall AG, Harrison CJ, Irving JA, Strefford JC.

Proc Natl Acad Sci U S A. 2008 Nov 4;105(44):17050-4. doi: 10.1073/pnas.0803494105. Epub 2008 Oct 28.


A novel PAX5-ELN fusion protein identified in B-cell acute lymphoblastic leukemia acts as a dominant negative on wild-type PAX5.

Bousquet M, Broccardo C, Quelen C, Meggetto F, Kuhlein E, Delsol G, Dastugue N, Brousset P.

Blood. 2007 Apr 15;109(8):3417-23. Epub 2006 Dec 19.


Identification of PML as novel PAX5 fusion partner in childhood acute lymphoblastic leukaemia.

Nebral K, K├Ânig M, Harder L, Siebert R, Haas OA, Strehl S.

Br J Haematol. 2007 Oct;139(2):269-74.


Wide diversity of PAX5 alterations in B-ALL: a Groupe Francophone de Cytogenetique Hematologique study.

Coyaud E, Struski S, Prade N, Familiades J, Eichner R, Quelen C, Bousquet M, Mugneret F, Talmant P, Pages MP, Lefebvre C, Penther D, Lippert E, Nadal N, Taviaux S, Poppe B, Luquet I, Baranger L, Eclache V, Radford I, Barin C, Mozziconacci MJ, Lafage-Pochitaloff M, Antoine-Poirel H, Charrin C, Perot C, Terre C, Brousset P, Dastugue N, Broccardo C.

Blood. 2010 Apr 15;115(15):3089-97. doi: 10.1182/blood-2009-07-234229. Epub 2010 Feb 16.


Oncogenic role of Pax5 in the T-lymphoid lineage upon ectopic expression from the immunoglobulin heavy-chain locus.

Souabni A, Jochum W, Busslinger M.

Blood. 2007 Jan 1;109(1):281-9. Epub 2006 Sep 12.


FOXP1 and PAX5 are rare but recurrent translocations partners in acute lymphoblastic leukemia.

Put N, Deeren D, Michaux L, Vandenberghe P.

Cancer Genet. 2011 Aug;204(8):462-4. doi: 10.1016/j.cancergen.2011.07.006.


Identification of Pax5 target genes in early B cell differentiation.

Pridans C, Holmes ML, Polli M, Wettenhall JM, Dakic A, Corcoran LM, Smyth GK, Nutt SL.

J Immunol. 2008 Feb 1;180(3):1719-28.


Transcription factor Pax5 activates the chromatin of key genes involved in B cell signaling, adhesion, migration, and immune function.

Schebesta A, McManus S, Salvagiotto G, Delogu A, Busslinger GA, Busslinger M.

Immunity. 2007 Jul;27(1):49-63. Epub 2007 Jul 19.


PAX5/TEL acts as a transcriptional repressor causing down-modulation of CD19, enhances migration to CXCL12, and confers survival advantage in pre-BI cells.

Fazio G, Palmi C, Rolink A, Biondi A, Cazzaniga G.

Cancer Res. 2008 Jan 1;68(1):181-9. doi: 10.1158/0008-5472.CAN-07-2778.


Integration of genomic and gene expression data of childhood ALL without known aberrations identifies subgroups with specific genetic hallmarks.

Bungaro S, Dell'Orto MC, Zangrando A, Basso D, Gorletta T, Lo Nigro L, Leszl A, Young BD, Basso G, Bicciato S, Biondi A, te Kronnie G, Cazzaniga G.

Genes Chromosomes Cancer. 2009 Jan;48(1):22-38. doi: 10.1002/gcc.20616.


PAX immunoreactivity identifies alveolar rhabdomyosarcoma.

Sullivan LM, Atkins KA, LeGallo RD.

Am J Surg Pathol. 2009 May;33(5):775-80. doi: 10.1097/PAS.0b013e318191614f.


PAX5-PML acts as a dual dominant-negative form of both PAX5 and PML.

Kurahashi S, Hayakawa F, Miyata Y, Yasuda T, Minami Y, Tsuzuki S, Abe A, Naoe T.

Oncogene. 2011 Apr 14;30(15):1822-30. doi: 10.1038/onc.2010.554. Epub 2011 Jan 10.


Dominant-negative mechanism of leukemogenic PAX5 fusions.

Kawamata N, Pennella MA, Woo JL, Berk AJ, Koeffler HP.

Oncogene. 2012 Feb 23;31(8):966-77. doi: 10.1038/onc.2011.291. Epub 2011 Jul 18.


Heterogeneous breakpoints in patients with acute lymphoblastic leukemia and the dic(9;20)(p11-13;q11) show recurrent involvement of genes at 20q11.21.

An Q, Wright SL, Moorman AV, Parker H, Griffiths M, Ross FM, Davies T, Harrison CJ, Strefford JC.

Haematologica. 2009 Aug;94(8):1164-9. doi: 10.3324/haematol.2008.002808. Epub 2009 Jul 7.


Identification and comparative analysis of Pax5 C-terminal isoforms expressed in human cord blood-derived B cell progenitors.

Sekine R, Kitamura T, Tsuji T, Tojo A.

Immunol Lett. 2007 Jul 31;111(1):21-5. Epub 2007 May 15.


Reporter gene insertions reveal a strictly B lymphoid-specific expression pattern of Pax5 in support of its B cell identity function.

Fuxa M, Busslinger M.

J Immunol. 2007 Mar 1;178(5):3031-7. Erratum in: J Immunol. 2007 Jun 15;178(12):8221.

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