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Results: 1 to 20 of 127

1.

Subunit organization of Mcm2-7 and the unequal role of active sites in ATP hydrolysis and viability.

Bochman ML, Bell SP, Schwacha A.

Mol Cell Biol. 2008 Oct;28(19):5865-73. doi: 10.1128/MCB.00161-08. Epub 2008 Jul 28.

PMID:
18662997
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

The Saccharomyces cerevisiae Mcm6/2 and Mcm5/3 ATPase active sites contribute to the function of the putative Mcm2-7 'gate'.

Bochman ML, Schwacha A.

Nucleic Acids Res. 2010 Oct;38(18):6078-88. doi: 10.1093/nar/gkq422. Epub 2010 May 19.

PMID:
20484375
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Differences in the single-stranded DNA binding activities of MCM2-7 and MCM467: MCM2 and MCM5 define a slow ATP-dependent step.

Bochman ML, Schwacha A.

J Biol Chem. 2007 Nov 16;282(46):33795-804. Epub 2007 Sep 25.

PMID:
17895243
[PubMed - indexed for MEDLINE]
Free Article
4.

ATP binding and hydrolysis by Mcm2 regulate DNA binding by Mcm complexes.

Stead BE, Sorbara CD, Brandl CJ, Davey MJ.

J Mol Biol. 2009 Aug 14;391(2):301-13. doi: 10.1016/j.jmb.2009.06.038. Epub 2009 Jun 21.

PMID:
19540846
[PubMed - indexed for MEDLINE]
5.

Reconstitution of the Mcm2-7p heterohexamer, subunit arrangement, and ATP site architecture.

Davey MJ, Indiani C, O'Donnell M.

J Biol Chem. 2003 Feb 14;278(7):4491-9. Epub 2002 Dec 11.

PMID:
12480933
[PubMed - indexed for MEDLINE]
Free Article
6.

Different phenotypes in vivo are associated with ATPase motif mutations in Schizosaccharomyces pombe minichromosome maintenance proteins.

Gómez EB, Catlett MG, Forsburg SL.

Genetics. 2002 Apr;160(4):1305-18.

PMID:
11973289
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

In the absence of ATPase activity, pre-RC formation is blocked prior to MCM2-7 hexamer dimerization.

Evrin C, Fernández-Cid A, Zech J, Herrera MC, Riera A, Clarke P, Brill S, Lurz R, Speck C.

Nucleic Acids Res. 2013 Mar 1;41(5):3162-72. doi: 10.1093/nar/gkt043. Epub 2013 Feb 1.

PMID:
23376927
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Roles of Mcm7 and Mcm4 subunits in the DNA helicase activity of the mouse Mcm4/6/7 complex.

You Z, Ishimi Y, Masai H, Hanaoka F.

J Biol Chem. 2002 Nov 8;277(45):42471-9. Epub 2002 Aug 30.

PMID:
12207017
[PubMed - indexed for MEDLINE]
Free Article
9.

The Mcm complex: unwinding the mechanism of a replicative helicase.

Bochman ML, Schwacha A.

Microbiol Mol Biol Rev. 2009 Dec;73(4):652-83. doi: 10.1128/MMBR.00019-09. Review.

PMID:
19946136
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Crystal structure of the hexameric replicative helicase RepA of plasmid RSF1010.

Niedenzu T, Röleke D, Bains G, Scherzinger E, Saenger W.

J Mol Biol. 2001 Feb 23;306(3):479-87.

PMID:
11178907
[PubMed - indexed for MEDLINE]
11.

The ATPase activity of MCM2-7 is dispensable for pre-RC assembly but is required for DNA unwinding.

Ying CY, Gautier J.

EMBO J. 2005 Dec 21;24(24):4334-44. Epub 2005 Nov 24.

PMID:
16369567
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Functional conservation of beta-hairpin DNA binding domains in the Mcm protein of Methanobacterium thermoautotrophicum and the Mcm5 protein of Saccharomyces cerevisiae.

Leon RP, Tecklenburg M, Sclafani RA.

Genetics. 2008 Aug;179(4):1757-68. doi: 10.1534/genetics.108.088690. Epub 2008 Jul 27.

PMID:
18660534
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Physical interactions among Mcm proteins and effects of Mcm dosage on DNA replication in Saccharomyces cerevisiae.

Lei M, Kawasaki Y, Tye BK.

Mol Cell Biol. 1996 Sep;16(9):5081-90.

PMID:
8756666
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

The hexameric eukaryotic MCM helicase: building symmetry from nonidentical parts.

Tye BK, Sawyer S.

J Biol Chem. 2000 Nov 10;275(45):34833-6. Review. No abstract available.

PMID:
10980206
[PubMed - indexed for MEDLINE]
Free Article
15.

Minichromosome maintenance helicase activity is controlled by N- and C-terminal motifs and requires the ATPase domain helix-2 insert.

Jenkinson ER, Chong JP.

Proc Natl Acad Sci U S A. 2006 May 16;103(20):7613-8. Epub 2006 May 5.

PMID:
16679413
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Structural biochemistry of ATP-driven dimerization and DNA-stimulated activation of SMC ATPases.

Lammens A, Schele A, Hopfner KP.

Curr Biol. 2004 Oct 5;14(19):1778-82.

PMID:
15458651
[PubMed - indexed for MEDLINE]
17.

Isolation and characterization of various complexes of the minichromosome maintenance proteins of Schizosaccharomyces pombe.

Lee JK, Hurwitz J.

J Biol Chem. 2000 Jun 23;275(25):18871-8.

PMID:
10770926
[PubMed - indexed for MEDLINE]
Free Article
18.

The eukaryotic Mcm2-7 replicative helicase.

Vijayraghavan S, Schwacha A.

Subcell Biochem. 2012;62:113-34. doi: 10.1007/978-94-007-4572-8_7. Review.

PMID:
22918583
[PubMed - indexed for MEDLINE]
19.

ATP hydrolysis by ORC catalyzes reiterative Mcm2-7 assembly at a defined origin of replication.

Bowers JL, Randell JC, Chen S, Bell SP.

Mol Cell. 2004 Dec 22;16(6):967-78.

PMID:
15610739
[PubMed - indexed for MEDLINE]
20.

The effects of oligomerization on Saccharomyces cerevisiae Mcm4/6/7 function.

Ma X, Stead BE, Rezvanpour A, Davey MJ.

BMC Biochem. 2010 Sep 22;11:37. doi: 10.1186/1471-2091-11-37.

PMID:
20860810
[PubMed - indexed for MEDLINE]
Free PMC Article

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