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Results: 1 to 20 of 88

1.

Itch: a HECT-type E3 ligase regulating immunity, skin and cancer.

Melino G, Gallagher E, Aqeilan RI, Knight R, Peschiaroli A, Rossi M, Scialpi F, Malatesta M, Zocchi L, Browne G, Ciechanover A, Bernassola F.

Cell Death Differ. 2008 Jul;15(7):1103-12. doi: 10.1038/cdd.2008.60. Review.

PMID:
18552861
[PubMed - indexed for MEDLINE]
Free Article
2.

The HECT family of E3 ubiquitin ligases: multiple players in cancer development.

Bernassola F, Karin M, Ciechanover A, Melino G.

Cancer Cell. 2008 Jul 8;14(1):10-21. doi: 10.1016/j.ccr.2008.06.001. Review.

PMID:
18598940
[PubMed - indexed for MEDLINE]
Free Article
3.

Atrophin-1-interacting protein 4/human Itch is a ubiquitin E3 ligase for human enhancer of filamentation 1 in transforming growth factor-beta signaling pathways.

Feng L, Guedes S, Wang T.

J Biol Chem. 2004 Jul 9;279(28):29681-90. Epub 2004 Mar 29.

PMID:
15051726
[PubMed - indexed for MEDLINE]
Free Article
4.

Smurf control in bone cells.

Xing L, Zhang M, Chen D.

J Cell Biochem. 2010 Jun 1;110(3):554-63. doi: 10.1002/jcb.22586. Review.

PMID:
20512916
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Recognition and ubiquitination of Notch by Itch, a hect-type E3 ubiquitin ligase.

Qiu L, Joazeiro C, Fang N, Wang HY, Elly C, Altman Y, Fang D, Hunter T, Liu YC.

J Biol Chem. 2000 Nov 17;275(46):35734-7.

PMID:
10940313
[PubMed - indexed for MEDLINE]
Free Article
6.

The E3 ubiquitin ligase ITCH negatively regulates canonical Wnt signaling by targeting dishevelled protein.

Wei W, Li M, Wang J, Nie F, Li L.

Mol Cell Biol. 2012 Oct;32(19):3903-12. doi: 10.1128/MCB.00251-12. Epub 2012 Jul 23.

PMID:
22826439
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Cbl-b and itch: key regulators of peripheral T-cell tolerance.

Venuprasad K.

Cancer Res. 2010 Apr 15;70(8):3009-12. doi: 10.1158/0008-5472.CAN-09-4076. Review.

PMID:
20395198
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Itch E3 ligase-mediated regulation of TGF-beta signaling by modulating smad2 phosphorylation.

Bai Y, Yang C, Hu K, Elly C, Liu YC.

Mol Cell. 2004 Sep 10;15(5):825-31.

PMID:
15350225
[PubMed - indexed for MEDLINE]
Free Article
9.

Itch E3 ubiquitin ligase regulates large tumor suppressor 1 stability [corrected].

Ho KC, Zhou Z, She YM, Chun A, Cyr TD, Yang X.

Proc Natl Acad Sci U S A. 2011 Mar 22;108(12):4870-5. doi: 10.1073/pnas.1101273108. Epub 2011 Mar 7. Erratum in: Proc Natl Acad Sci U S A.2011 May 3;108(18):8914.

PMID:
21383157
[PubMed - indexed for MEDLINE]
Free PMC Article
10.
11.

The E3 ubiquitin ligase Itch controls the protein stability of p63.

Rossi M, Aqeilan RI, Neale M, Candi E, Salomoni P, Knight RA, Croce CM, Melino G.

Proc Natl Acad Sci U S A. 2006 Aug 22;103(34):12753-8. Epub 2006 Aug 14.

PMID:
16908849
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Reciprocal regulation of the ubiquitin ligase Itch and the epidermal growth factor receptor signaling.

Azakir BA, Angers A.

Cell Signal. 2009 Aug;21(8):1326-36. doi: 10.1016/j.cellsig.2009.03.020. Epub 2009 Mar 31.

PMID:
19341794
[PubMed - indexed for MEDLINE]
13.

The E3 ligase Aip4/Itch ubiquitinates and targets ErbB-4 for degradation.

Omerovic J, Santangelo L, Puggioni EM, Marrocco J, Dall'Armi C, Palumbo C, Belleudi F, Di Marcotullio L, Frati L, Torrisi MR, Cesareni G, Gulino A, Alimandi M.

FASEB J. 2007 Sep;21(11):2849-62. Epub 2007 Apr 26.

PMID:
17463226
[PubMed - indexed for MEDLINE]
Free Article
14.

The itchy locus encodes a novel ubiquitin protein ligase that is disrupted in a18H mice.

Perry WL, Hustad CM, Swing DA, O'Sullivan TN, Jenkins NA, Copeland NG.

Nat Genet. 1998 Feb;18(2):143-6.

PMID:
9462742
[PubMed - indexed for MEDLINE]
15.

Itch self-polyubiquitylation occurs through lysine-63 linkages.

Scialpi F, Malatesta M, Peschiaroli A, Rossi M, Melino G, Bernassola F.

Biochem Pharmacol. 2008 Dec 1;76(11):1515-21. doi: 10.1016/j.bcp.2008.07.028. Epub 2008 Jul 31.

PMID:
18718449
[PubMed - indexed for MEDLINE]
16.

The E3 ubiquitin ligase Itch regulates sorting nexin 9 through an unconventional substrate recognition domain.

Baumann C, Lindholm CK, Rimoldi D, Lévy F.

FEBS J. 2010 Jul;277(13):2803-14. doi: 10.1111/j.1742-4658.2010.07698.x. Epub 2010 May 20.

PMID:
20491914
[PubMed - indexed for MEDLINE]
17.

Itch, an E3 ligase of Oct4, is required for embryonic stem cell self-renewal and pluripotency induction.

Liao B, Zhong X, Xu H, Xiao F, Fang Z, Gu J, Chen Y, Zhao Y, Jin Y.

J Cell Physiol. 2013 Jul;228(7):1443-51. doi: 10.1002/jcp.24297.

PMID:
23255053
[PubMed - indexed for MEDLINE]
18.

The E3 ubiquitin ligase Itch regulates tumor suppressor protein RASSF5/NORE1 stability in an acetylation-dependent manner.

Suryaraja R, Anitha M, Anbarasu K, Kumari G, Mahalingam S.

Cell Death Dis. 2013 Mar 28;4:e565. doi: 10.1038/cddis.2013.91.

PMID:
23538446
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Interaction between two ubiquitin-protein isopeptide ligases of different classes, CBLC and AIP4/ITCH.

Courbard JR, Fiore F, Adélaïde J, Borg JP, Birnbaum D, Ollendorff V.

J Biol Chem. 2002 Nov 22;277(47):45267-75. Epub 2002 Sep 10.

PMID:
12226085
[PubMed - indexed for MEDLINE]
Free Article
20.

The HECT domain ligase itch ubiquitinates endophilin and localizes to the trans-Golgi network and endosomal system.

Angers A, Ramjaun AR, McPherson PS.

J Biol Chem. 2004 Mar 19;279(12):11471-9. Epub 2003 Dec 18.

PMID:
14684745
[PubMed - indexed for MEDLINE]
Free Article

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