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Results: 1 to 20 of 93

1.

Pharmacological blockade of A2A receptors prevents dermal fibrosis in a model of elevated tissue adenosine.

Fernández P, Trzaska S, Wilder T, Chiriboga L, Blackburn MR, Cronstein BN, Chan ES.

Am J Pathol. 2008 Jun;172(6):1675-82. doi: 10.2353/ajpath.2008.070952. Epub 2008 May 8.

PMID:
18467695
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Adenosine A2A receptors in diffuse dermal fibrosis: pathogenic role in human dermal fibroblasts and in a murine model of scleroderma.

Chan ES, Fernandez P, Merchant AA, Montesinos MC, Trzaska S, Desai A, Tung CF, Khoa DN, Pillinger MH, Reiss AB, Tomic-Canic M, Chen JF, Schwarzschild MA, Cronstein BN.

Arthritis Rheum. 2006 Aug;54(8):2632-42.

PMID:
16871530
[PubMed - indexed for MEDLINE]
Free Article
3.

Adenosine A2A receptor blockade or deletion diminishes fibrocyte accumulation in the skin in a murine model of scleroderma, bleomycin-induced fibrosis.

Katebi M, Fernandez P, Chan ES, Cronstein BN.

Inflammation. 2008 Oct;31(5):299-303. doi: 10.1007/s10753-008-9078-y.

PMID:
18709547
[PubMed - indexed for MEDLINE]
4.

Partially adenosine deaminase-deficient mice develop pulmonary fibrosis in association with adenosine elevations.

Chunn JL, Mohsenin A, Young HW, Lee CG, Elias JA, Kellems RE, Blackburn MR.

Am J Physiol Lung Cell Mol Physiol. 2006 Mar;290(3):L579-87. Epub 2005 Oct 28.

PMID:
16258000
[PubMed - indexed for MEDLINE]
Free Article
5.

Adenosine A(2A) receptors play a role in the pathogenesis of hepatic cirrhosis.

Chan ES, Montesinos MC, Fernandez P, Desai A, Delano DL, Yee H, Reiss AB, Pillinger MH, Chen JF, Schwarzschild MA, Friedman SL, Cronstein BN.

Br J Pharmacol. 2006 Aug;148(8):1144-55. Epub 2006 Jun 19.

PMID:
16783407
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Adenosine A(2A) receptor activation prevents progressive kidney fibrosis in a model of immune-associated chronic inflammation.

Garcia GE, Truong LD, Chen JF, Johnson RJ, Feng L.

Kidney Int. 2011 Aug;80(4):378-88. doi: 10.1038/ki.2011.101. Epub 2011 Apr 20.

PMID:
21508927
[PubMed - indexed for MEDLINE]
7.

Insulin-like growth factor binding protein 5 induces skin fibrosis: A novel murine model for dermal fibrosis.

Yasuoka H, Jukic DM, Zhou Z, Choi AM, Feghali-Bostwick CA.

Arthritis Rheum. 2006 Sep;54(9):3001-10.

PMID:
16947625
[PubMed - indexed for MEDLINE]
Free Article
8.

Extracellular generation of adenosine by the ectonucleotidases CD39 and CD73 promotes dermal fibrosis.

Fernández P, Perez-Aso M, Smith G, Wilder T, Trzaska S, Chiriboga L, Franks A Jr, Robson SC, Cronstein BN, Chan ES.

Am J Pathol. 2013 Dec;183(6):1740-6. doi: 10.1016/j.ajpath.2013.08.024.

PMID:
24266925
[PubMed - indexed for MEDLINE]
9.

Genetic removal of the A2A adenosine receptor enhances pulmonary inflammation, mucin production, and angiogenesis in adenosine deaminase-deficient mice.

Mohsenin A, Mi T, Xia Y, Kellems RE, Chen JF, Blackburn MR.

Am J Physiol Lung Cell Mol Physiol. 2007 Sep;293(3):L753-61. Epub 2007 Jun 29.

PMID:
17601796
[PubMed - indexed for MEDLINE]
Free Article
10.

Blocking adenosine A2A receptor reduces peritoneal fibrosis in two independent experimental models.

Nakav S, Kachko L, Vorobiov M, Rogachev B, Chaimovitz C, Zlotnik M, Douvdevani A.

Nephrol Dial Transplant. 2009 Aug;24(8):2392-9. doi: 10.1093/ndt/gfp041. Epub 2009 Feb 16.

PMID:
19221177
[PubMed - indexed for MEDLINE]
Free Article
11.

Increased severity of bleomycin-induced skin fibrosis in mice with leukocyte-specific protein 1 deficiency.

Wang J, Jiao H, Stewart TL, Shankowsky HA, Scott PG, Tredget EE.

J Invest Dermatol. 2008 Dec;128(12):2767-76. doi: 10.1038/jid.2008.164. Epub 2008 Jun 26.

PMID:
18580965
[PubMed - indexed for MEDLINE]
Free Article
12.

Endothelin 1 contributes to the effect of transforming growth factor beta1 on wound repair and skin fibrosis.

Lagares D, García-Fernández RA, Jiménez CL, Magán-Marchal N, Busnadiego O, Lamas S, Rodríguez-Pascual F.

Arthritis Rheum. 2010 Mar;62(3):878-89. doi: 10.1002/art.27307.

PMID:
20131241
[PubMed - indexed for MEDLINE]
Free Article
13.

Peripheral adenosine A2A receptors are involved in carrageenan-induced mechanical hyperalgesia in mice.

Li L, Hao JX, Fredholm BB, Schulte G, Wiesenfeld-Hallin Z, Xu XJ.

Neuroscience. 2010 Oct 27;170(3):923-8. doi: 10.1016/j.neuroscience.2010.07.045. Epub 2010 Aug 3.

PMID:
20678550
[PubMed - indexed for MEDLINE]
14.

Trichostatin A prevents the accumulation of extracellular matrix in a mouse model of bleomycin-induced skin fibrosis.

Huber LC, Distler JH, Moritz F, Hemmatazad H, Hauser T, Michel BA, Gay RE, Matucci-Cerinic M, Gay S, Distler O, Jüngel A.

Arthritis Rheum. 2007 Aug;56(8):2755-64.

PMID:
17665426
[PubMed - indexed for MEDLINE]
Free Article
15.

Loss of peroxisome proliferator-activated receptor gamma in mouse fibroblasts results in increased susceptibility to bleomycin-induced skin fibrosis.

Kapoor M, McCann M, Liu S, Huh K, Denton CP, Abraham DJ, Leask A.

Arthritis Rheum. 2009 Sep;60(9):2822-9. doi: 10.1002/art.24761.

PMID:
19714649
[PubMed - indexed for MEDLINE]
Free Article
16.

Disruption of tumor necrosis factor receptor p55 impairs collagen turnover in experimentally induced sclerodermic skin fibroblasts.

Murota H, Hamasaki Y, Nakashima T, Yamamoto K, Katayama I, Matsuyama T.

Arthritis Rheum. 2003 Apr;48(4):1117-25.

PMID:
12687556
[PubMed - indexed for MEDLINE]
Free Article
17.

Topical application of a peptide inhibitor of transforming growth factor-beta1 ameliorates bleomycin-induced skin fibrosis.

Santiago B, Gutierrez-Cañas I, Dotor J, Palao G, Lasarte JJ, Ruiz J, Prieto J, Borrás-Cuesta F, Pablos JL.

J Invest Dermatol. 2005 Sep;125(3):450-5.

PMID:
16117784
[PubMed - indexed for MEDLINE]
Free Article
18.

Adenosine A2A receptor activation stimulates collagen production in sclerodermic dermal fibroblasts either directly and through a cross-talk with the cannabinoid system.

Lazzerini PE, Natale M, Gianchecchi E, Capecchi PL, Montilli C, Zimbone S, Castrichini M, Balistreri E, Ricci G, Selvi E, Garcia-Gonzalez E, Galeazzi M, Laghi-Pasini F.

J Mol Med (Berl). 2012 Mar;90(3):331-42. doi: 10.1007/s00109-011-0824-5. Epub 2011 Oct 28.

PMID:
22033526
[PubMed - indexed for MEDLINE]
19.

A novel inhibitor of Smad-dependent transcriptional activation suppresses tissue fibrosis in mouse models of systemic sclerosis.

Hasegawa M, Matsushita Y, Horikawa M, Higashi K, Tomigahara Y, Kaneko H, Shirasaki F, Fujimoto M, Takehara K, Sato S.

Arthritis Rheum. 2009 Nov;60(11):3465-75. doi: 10.1002/art.24934.

PMID:
19877032
[PubMed - indexed for MEDLINE]
Free Article
20.

Lack of skin fibrosis in tight skin (TSK) mice with targeted mutation in the interleukin-4R alpha and transforming growth factor-beta genes.

McGaha T, Saito S, Phelps RG, Gordon R, Noben-Trauth N, Paul WE, Bona C.

J Invest Dermatol. 2001 Jan;116(1):136-43.

PMID:
11168809
[PubMed - indexed for MEDLINE]
Free Article

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