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Polymorphisms of the HNF1A gene encoding hepatocyte nuclear factor-1 alpha are associated with C-reactive protein.

Reiner AP, Barber MJ, Guan Y, Ridker PM, Lange LA, Chasman DI, Walston JD, Cooper GM, Jenny NS, Rieder MJ, Durda JP, Smith JD, Novembre J, Tracy RP, Rotter JI, Stephens M, Nickerson DA, Krauss RM.

Am J Hum Genet. 2008 May;82(5):1193-201. doi: 10.1016/j.ajhg.2008.03.017. Epub 2008 Apr 24.


Genome-wide association with C-reactive protein levels in CLHNS: evidence for the CRP and HNF1A loci and their interaction with exposure to a pathogenic environment.

Wu Y, McDade TW, Kuzawa CW, Borja J, Li Y, Adair LS, Mohlke KL, Lange LA.

Inflammation. 2012 Apr;35(2):574-83. doi: 10.1007/s10753-011-9348-y.


Common coding variants of the HNF1A gene are associated with multiple cardiovascular risk phenotypes in community-based samples of younger and older European-American adults: the Coronary Artery Risk Development in Young Adults Study and The Cardiovascular Health Study.

Reiner AP, Gross MD, Carlson CS, Bielinski SJ, Lange LA, Fornage M, Jenny NS, Walston J, Tracy RP, Williams OD, Jacobs DR Jr, Nickerson DA.

Circ Cardiovasc Genet. 2009 Jun;2(3):244-54. doi: 10.1161/CIRCGENETICS.108.839506. Epub 2009 Apr 6.


Assessing the association of the HNF1A G319S variant with C-reactive protein in Aboriginal Canadians: a population-based epidemiological study.

Ley SH, Hegele RA, Connelly PW, Harris SB, Mamakeesick M, Cao H, Gittelsohn J, Retnakaran R, Zinman B, Hanley AJ.

Cardiovasc Diabetol. 2010 Aug 18;9:39. doi: 10.1186/1475-2840-9-39.


Genome-wide association of lipid-lowering response to statins in combined study populations.

Barber MJ, Mangravite LM, Hyde CL, Chasman DI, Smith JD, McCarty CA, Li X, Wilke RA, Rieder MJ, Williams PT, Ridker PM, Chatterjee A, Rotter JI, Nickerson DA, Stephens M, Krauss RM.

PLoS One. 2010 Mar 22;5(3):e9763. doi: 10.1371/journal.pone.0009763.


Effect of obesity on the association between common variations in the HNF1A gene region and C-reactive protein level in Taiwanese.

Hsu LA, Ko YL, Teng MS, Wu S, Chou HH, Chang PY, Chang HH.

Clin Chim Acta. 2011 Apr 11;412(9-10):725-9. doi: 10.1016/j.cca.2010.12.027. Epub 2010 Dec 31.


HNF1A gene polymorphisms and cardiovascular risk factors in individuals with late-onset autosomal dominant diabetes: a cross-sectional study.

Giuffrida FM, Furuzawa GK, Kasamatsu TS, Oliveira MM, Reis AF, Dib SA.

Cardiovasc Diabetol. 2009 Jun 2;8:28. doi: 10.1186/1475-2840-8-28.


Genetic risk assessment for cardiovascular disease with seven genes associated with plasma C-reactive protein concentrations in Asian populations.

Hong EP, Kim DH, Suh JG, Park JW.

Hypertens Res. 2014 Jul;37(7):692-8. doi: 10.1038/hr.2014.56. Epub 2014 Mar 27.


Assessment of high-sensitivity C-reactive protein levels as diagnostic discriminator of maturity-onset diabetes of the young due to HNF1A mutations.

Owen KR, Thanabalasingham G, James TJ, Karpe F, Farmer AJ, McCarthy MI, Gloyn AL.

Diabetes Care. 2010 Sep;33(9):1919-24. doi: 10.2337/dc10-0288. Epub 2010 Aug 19.


Effects of hepatocyte nuclear factor-1A and -4A on pancreatic stone protein/regenerating protein and C-reactive protein gene expression: implications for maturity-onset diabetes of the young.

Kyithar MP, Bonner C, Bacon S, Kilbride SM, Schmid J, Graf R, Prehn JH, Byrne MM.

J Transl Med. 2013 Jun 26;11:156. doi: 10.1186/1479-5876-11-156.


A large multi-centre European study validates high-sensitivity C-reactive protein (hsCRP) as a clinical biomarker for the diagnosis of diabetes subtypes.

Thanabalasingham G, Shah N, Vaxillaire M, Hansen T, Tuomi T, Gašperíková D, Szopa M, Tjora E, James TJ, Kokko P, Loiseleur F, Andersson E, Gaget S, Isomaa B, Nowak N, Raeder H, Stanik J, Njolstad PR, Malecki MT, Klimes I, Groop L, Pedersen O, Froguel P, McCarthy MI, Gloyn AL, Owen KR.

Diabetologia. 2011 Nov;54(11):2801-10. doi: 10.1007/s00125-011-2261-y. Epub 2011 Aug 4.


High-sensitivity CRP discriminates HNF1A-MODY from other subtypes of diabetes.

McDonald TJ, Shields BM, Lawry J, Owen KR, Gloyn AL, Ellard S, Hattersley AT.

Diabetes Care. 2011 Aug;34(8):1860-2. doi: 10.2337/dc11-0323. Epub 2011 Jun 23.


Genetic and functional analyses of MRAS and HNF1A genes in diabetes and diabetic nephropathy.

Horová E, Prázný M, Kaňková K, Brismar K, Gu HF.

Folia Biol (Praha). 2012;58(3):121-7.


Hepatic nuclear factor 1-alpha: inflammation, genetics, and atherosclerosis.

Armendariz AD, Krauss RM.

Curr Opin Lipidol. 2009 Apr;20(2):106-11. Review.


Genetic associations with C-reactive protein level and white blood cell count in the KARE study.

Kong M, Lee C.

Int J Immunogenet. 2013 Apr;40(2):120-5. doi: 10.1111/j.1744-313X.2012.01141.x. Epub 2012 Jul 13.


C-reactive protein (CRP) gene polymorphisms, CRP levels, and risk of incident coronary heart disease in two nested case-control studies.

Pai JK, Mukamal KJ, Rexrode KM, Rimm EB.

PLoS One. 2008 Jan 2;3(1):e1395. doi: 10.1371/journal.pone.0001395.

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