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Items: 1 to 20 of 148

1.

A plant pathogen virulence factor inhibits the eukaryotic proteasome by a novel mechanism.

Groll M, Schellenberg B, Bachmann AS, Archer CR, Huber R, Powell TK, Lindow S, Kaiser M, Dudler R.

Nature. 2008 Apr 10;452(7188):755-8. doi: 10.1038/nature06782.

PMID:
18401409
2.

Pseudomonas syringae virulence factor syringolin A counteracts stomatal immunity by proteasome inhibition.

Schellenberg B, Ramel C, Dudler R.

Mol Plant Microbe Interact. 2010 Oct;23(10):1287-93. doi: 10.1094/MPMI-04-10-0094.

3.

Biosynthesis of the proteasome inhibitor syringolin A: the ureido group joining two amino acids originates from bicarbonate.

Ramel C, Tobler M, Meyer M, Bigler L, Ebert MO, Schellenberg B, Dudler R.

BMC Biochem. 2009 Oct 28;10:26. doi: 10.1186/1471-2091-10-26.

4.

Activity enhancement of the synthetic syrbactin proteasome inhibitor hybrid and biological evaluation in tumor cells.

Archer CR, Groll M, Stein ML, Schellenberg B, Clerc J, Kaiser M, Kondratyuk TP, Pezzuto JM, Dudler R, Bachmann AS.

Biochemistry. 2012 Aug 28;51(34):6880-8. Epub 2012 Aug 17.

PMID:
22870914
5.

Proteasome activity imaging and profiling characterizes bacterial effector syringolin A.

Kolodziejek I, Misas-Villamil JC, Kaschani F, Clerc J, Gu C, Krahn D, Niessen S, Verdoes M, Willems LI, Overkleeft HS, Kaiser M, van der Hoorn RA.

Plant Physiol. 2011 Jan;155(1):477-89. doi: 10.1104/pp.110.163733. Epub 2010 Nov 2.

6.

Arabidopsis YELLOW STRIPE-LIKE7 (YSL7) and YSL8 transporters mediate uptake of Pseudomonas virulence factor syringolin A into plant cells.

Hofstetter SS, Dudnik A, Widmer H, Dudler R.

Mol Plant Microbe Interact. 2013 Nov;26(11):1302-11. doi: 10.1094/MPMI-06-13-0163-R.

7.

Syrbactin class proteasome inhibitor-induced apoptosis and autophagy occurs in association with p53 accumulation and Akt/PKB activation in neuroblastoma.

Archer CR, Koomoa DL, Mitsunaga EM, Clerc J, Shimizu M, Kaiser M, Schellenberg B, Dudler R, Bachmann AS.

Biochem Pharmacol. 2010 Jul 15;80(2):170-8. doi: 10.1016/j.bcp.2010.03.031. Epub 2010 Apr 1.

PMID:
20362557
8.

The natural product hybrid of Syringolin A and Glidobactin A synergizes proteasome inhibition potency with subsite selectivity.

Clerc J, Li N, Krahn D, Groll M, Bachmann AS, Florea BI, Overkleeft HS, Kaiser M.

Chem Commun (Camb). 2011 Jan 7;47(1):385-7. doi: 10.1039/c0cc02238a. Epub 2010 Sep 7.

PMID:
20830349
9.

Regulation of biosynthesis of syringolin A, a Pseudomonas syringae virulence factor targeting the host proteasome.

Ramel C, Baechler N, Hildbrand M, Meyer M, Schädeli D, Dudler R.

Mol Plant Microbe Interact. 2012 Sep;25(9):1198-208. doi: 10.1094/MPMI-03-12-0070-R.

10.

Syringolin B-inspired proteasome inhibitor analogue TIR-203 exhibits enhanced biological activity in multiple myeloma and neuroblastoma.

Opoku-Ansah J, Ibarra-Rivera TR, Pirrung MC, Bachmann AS.

Pharm Biol. 2012 Jan;50(1):25-9. doi: 10.3109/13880209.2011.626784.

PMID:
22196580
11.

Manipulation of host proteasomes as a virulence mechanism of plant pathogens.

Dudler R.

Annu Rev Phytopathol. 2013;51:521-42. doi: 10.1146/annurev-phyto-082712-102312. Epub 2013 May 31. Review.

PMID:
23725468
12.

Heterologous expression of a Photorhabdus luminescens syrbactin-like gene cluster results in production of the potent proteasome inhibitor glidobactin A.

Dudnik A, Bigler L, Dudler R.

Microbiol Res. 2013 Feb 22;168(2):73-6. doi: 10.1016/j.micres.2012.09.006. Epub 2012 Oct 15.

13.

Pseudomonas syringae pv. syringae uses proteasome inhibitor syringolin A to colonize from wound infection sites.

Misas-Villamil JC, Kolodziejek I, Crabill E, Kaschani F, Niessen S, Shindo T, Kaiser M, Alfano JR, van der Hoorn RA.

PLoS Pathog. 2013 Mar;9(3):e1003281. doi: 10.1371/journal.ppat.1003281. Epub 2013 Mar 28.

14.
15.

The PseEF efflux system is a virulence factor of Pseudomonas syringae pv. syringae.

Cho H, Kang H.

J Microbiol. 2012 Feb;50(1):79-90. doi: 10.1007/s12275-012-1353-9. Epub 2012 Feb 27.

PMID:
22367941
16.

Pseudomonas syringae pv. phaseolicola effector HopF1 inhibits pathogen-associated molecular pattern-triggered immunity in a RIN4-independent manner in common bean (Phaseolus vulgaris).

Hou S, Mu R, Ma G, Xu X, Zhang C, Yang Y, Wu D.

FEMS Microbiol Lett. 2011 Oct;323(1):35-43. doi: 10.1111/j.1574-6968.2011.02356.x. Epub 2011 Aug 5.

17.

The type III effector repertoire of Pseudomonas syringae pv. syringae B728a and its role in survival and disease on host and non-host plants.

Vinatzer BA, Teitzel GM, Lee MW, Jelenska J, Hotton S, Fairfax K, Jenrette J, Greenberg JT.

Mol Microbiol. 2006 Oct;62(1):26-44. Epub 2006 Aug 30.

18.

TMC-95-based inhibitor design provides evidence for the catalytic versatility of the proteasome.

Groll M, Götz M, Kaiser M, Weyher E, Moroder L.

Chem Biol. 2006 Jun;13(6):607-14.

19.

Novel tetra-acridine derivatives as dual inhibitors of topoisomerase II and the human proteasome.

Vispé S, Vandenberghe I, Robin M, Annereau JP, Créancier L, Pique V, Galy JP, Kruczynski A, Barret JM, Bailly C.

Biochem Pharmacol. 2007 Jun 15;73(12):1863-72. Epub 2007 Mar 3.

PMID:
17391647
20.

Functional analysis of genes involved in the synthesis of syringolin A by Pseudomonas syringae pv. syringae B301 D-R.

Amrein H, Makart S, Granado J, Shakya R, Schneider-Pokorny J, Dudler R.

Mol Plant Microbe Interact. 2004 Jan;17(1):90-7.

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