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Results: 1 to 20 of 93

1.

Effects of simvastatin on cerebrospinal fluid biomarkers and cognition in middle-aged adults at risk for Alzheimer's disease.

Carlsson CM, Gleason CE, Hess TM, Moreland KA, Blazel HM, Koscik RL, Schreiber NT, Johnson SC, Atwood CS, Puglielli L, Hermann BP, McBride PE, Stein JH, Sager MA, Asthana S.

J Alzheimers Dis. 2008 Mar;13(2):187-97.

PMID:
18376061
[PubMed - indexed for MEDLINE]
2.

Effect of statins on Alzheimer's disease biomarkers in cerebrospinal fluid.

Riekse RG, Li G, Petrie EC, Leverenz JB, Vavrek D, Vuletic S, Albers JJ, Montine TJ, Lee VM, Lee M, Seubert P, Galasko D, Schellenberg GD, Hazzard WR, Peskind ER.

J Alzheimers Dis. 2006 Dec;10(4):399-406.

PMID:
17183151
[PubMed - indexed for MEDLINE]
3.

Cystatin C levels are positively correlated with both Abeta42 and tau levels in cerebrospinal fluid in persons with Alzheimer's disease, mild cognitive impairment, and healthy controls.

Sundelöf J, Sundström J, Hansson O, Eriksdotter-Jönhagen M, Giedraitis V, Larsson A, Degerman-Gunnarsson M, Ingelsson M, Minthon L, Blennow K, Kilander L, Basun H, Lannfelt L.

J Alzheimers Dis. 2010;21(2):471-8. doi: 10.3233/JAD-2010-091594.

PMID:
20555147
[PubMed - indexed for MEDLINE]
4.

A randomized, double-blind, placebo-controlled trial of simvastatin to treat Alzheimer disease.

Sano M, Bell KL, Galasko D, Galvin JE, Thomas RG, van Dyck CH, Aisen PS.

Neurology. 2011 Aug 9;77(6):556-63. doi: 10.1212/WNL.0b013e318228bf11. Epub 2011 Jul 27.

PMID:
21795660
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Statin treatment and a disease-specific pattern of beta-amyloid peptides in Alzheimer's disease.

Höglund K, Syversen S, Lewczuk P, Wallin A, Wiltfang J, Blennow K.

Exp Brain Res. 2005 Jul;164(2):205-14. Epub 2005 Jun 4.

PMID:
15937702
[PubMed - indexed for MEDLINE]
6.

Treatment with simvastatin in normocholesterolemic patients with Alzheimer's disease: A 26-week randomized, placebo-controlled, double-blind trial.

Simons M, Schwärzler F, Lütjohann D, von Bergmann K, Beyreuther K, Dichgans J, Wormstall H, Hartmann T, Schulz JB.

Ann Neurol. 2002 Sep;52(3):346-50.

PMID:
12205648
[PubMed - indexed for MEDLINE]
7.

CSF amyloid-beta and tau proteins, and cognitive performance, in early and untreated Parkinson's disease: the Norwegian ParkWest study.

Alves G, Brønnick K, Aarsland D, Blennow K, Zetterberg H, Ballard C, Kurz MW, Andreasson U, Tysnes OB, Larsen JP, Mulugeta E.

J Neurol Neurosurg Psychiatry. 2010 Oct;81(10):1080-6. doi: 10.1136/jnnp.2009.199950. Epub 2010 Jun 14.

PMID:
20547614
[PubMed - indexed for MEDLINE]
8.

Effect of apolipoprotein E genotype and diet on apolipoprotein E lipidation and amyloid peptides: randomized clinical trial.

Hanson AJ, Bayer-Carter JL, Green PS, Montine TJ, Wilkinson CW, Baker LD, Watson GS, Bonner LM, Callaghan M, Leverenz JB, Tsai E, Postupna N, Zhang J, Lampe J, Craft S.

JAMA Neurol. 2013 Aug;70(8):972-80. doi: 10.1001/jamaneurol.2013.396.

PMID:
23779114
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

The effects of ramipril in individuals at risk for Alzheimer's disease: results of a pilot clinical trial.

Wharton W, Stein JH, Korcarz C, Sachs J, Olson SR, Zetterberg H, Dowling M, Ye S, Gleason CE, Underbakke G, Jacobson LE, Johnson SC, Sager MA, Asthana S, Carlsson CM.

J Alzheimers Dis. 2012;32(1):147-56.

PMID:
22776970
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Longitudinal change of biomarkers in cognitive decline.

Lo RY, Hubbard AE, Shaw LM, Trojanowski JQ, Petersen RC, Aisen PS, Weiner MW, Jagust WJ; Alzheimer's Disease Neuroimaging Initiative.

Arch Neurol. 2011 Oct;68(10):1257-66. doi: 10.1001/archneurol.2011.123. Epub 2011 Jun 13.

PMID:
21670386
[PubMed - indexed for MEDLINE]
11.

Role of family history for Alzheimer biomarker abnormalities in the adult children study.

Xiong C, Roe CM, Buckles V, Fagan A, Holtzman D, Balota D, Duchek J, Storandt M, Mintun M, Grant E, Snyder AZ, Head D, Benzinger TL, Mettenburg J, Csernansky J, Morris JC.

Arch Neurol. 2011 Oct;68(10):1313-9. doi: 10.1001/archneurol.2011.208.

PMID:
21987546
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

The effect of simvastatin treatment on the amyloid precursor protein and brain cholesterol metabolism in patients with Alzheimer's disease.

Hoglund K, Thelen KM, Syversen S, Sjogren M, von Bergmann K, Wallin A, Vanmechelen E, Vanderstichele H, Lutjohann D, Blennow K.

Dement Geriatr Cogn Disord. 2005;19(5-6):256-65. Epub 2005 Mar 21.

PMID:
15785028
[PubMed - indexed for MEDLINE]
13.

Magnetic resonance imaging improves cerebrospinal fluid biomarkers in the early detection of Alzheimer's disease.

Brys M, Glodzik L, Mosconi L, Switalski R, De Santi S, Pirraglia E, Rich K, Kim BC, Mehta P, Zinkowski R, Pratico D, Wallin A, Zetterberg H, Tsui WH, Rusinek H, Blennow K, de Leon MJ.

J Alzheimers Dis. 2009;16(2):351-62. doi: 10.3233/JAD-2009-0968.

PMID:
19221425
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Amyloid-β oligomers in cerebrospinal fluid are associated with cognitive decline in patients with Alzheimer's disease.

Santos AN, Ewers M, Minthon L, Simm A, Silber RE, Blennow K, Prvulovic D, Hansson O, Hampel H.

J Alzheimers Dis. 2012;29(1):171-6. doi: 10.3233/JAD-2012-111361.

PMID:
22214781
[PubMed - indexed for MEDLINE]
15.

Rapid progression from mild cognitive impairment to Alzheimer's disease in subjects with elevated levels of tau in cerebrospinal fluid and the APOE epsilon4/epsilon4 genotype.

Blom ES, Giedraitis V, Zetterberg H, Fukumoto H, Blennow K, Hyman BT, Irizarry MC, Wahlund LO, Lannfelt L, Ingelsson M.

Dement Geriatr Cogn Disord. 2009;27(5):458-64. doi: 10.1159/000216841. Epub 2009 May 7.

PMID:
19420940
[PubMed - indexed for MEDLINE]
16.

Assessment of cerebrospinal fluid (CSF) beta-amyloid (1-42), phosphorylated tau (ptau-181) and total Tau protein in patients with Alzheimer's disease (AD) and other dementia at Siriraj Hospital, Thailand.

Thaweepoksomboon J, Senanarong V, Poungvarin N, Chakorn T, Siwasariyanon N, Washirutmangkur L, Udompunthuruk S.

J Med Assoc Thai. 2011 Feb;94 Suppl 1:S77-83.

PMID:
21721431
[PubMed - indexed for MEDLINE]
17.

Effects of simvastatin on cholesterol metabolism and Alzheimer disease biomarkers.

Serrano-Pozo A, Vega GL, Lütjohann D, Locascio JJ, Tennis MK, Deng A, Atri A, Hyman BT, Irizarry MC, Growdon JH.

Alzheimer Dis Assoc Disord. 2010 Jul-Sep;24(3):220-6. doi: 10.1097/WAD.0b013e3181d61fea.

PMID:
20473136
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Simvastatin strongly reduces levels of Alzheimer's disease beta -amyloid peptides Abeta 42 and Abeta 40 in vitro and in vivo.

Fassbender K, Simons M, Bergmann C, Stroick M, Lutjohann D, Keller P, Runz H, Kuhl S, Bertsch T, von Bergmann K, Hennerici M, Beyreuther K, Hartmann T.

Proc Natl Acad Sci U S A. 2001 May 8;98(10):5856-61. Epub 2001 Apr 10.

PMID:
11296263
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Statins for the treatment of dementia.

McGuinness B, O'Hare J, Craig D, Bullock R, Malouf R, Passmore P.

Cochrane Database Syst Rev. 2010 Aug 4;(8):CD007514. doi: 10.1002/14651858.CD007514.pub2. Review. Update in: Cochrane Database Syst Rev. 2014;7:CD007514.

PMID:
20687089
[PubMed - indexed for MEDLINE]
20.

Genetic loci associated with Alzheimer's disease and cerebrospinal fluid biomarkers in a Finnish case-control cohort.

Elias-Sonnenschein LS, Helisalmi S, Natunen T, Hall A, Paajanen T, Herukka SK, Laitinen M, Remes AM, Koivisto AM, Mattila KM, Lehtimäki T, Verhey FR, Visser PJ, Soininen H, Hiltunen M.

PLoS One. 2013;8(4):e59676. doi: 10.1371/journal.pone.0059676. Epub 2013 Apr 3.

PMID:
23573206
[PubMed - indexed for MEDLINE]
Free PMC Article

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