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Items: 1 to 20 of 127

1.

Targeting gene expression to cones with human cone opsin promoters in recombinant AAV.

Komáromy AM, Alexander JJ, Cooper AE, Chiodo VA, Glushakova LG, Acland GM, Hauswirth WW, Aguirre GD.

Gene Ther. 2008 Jul;15(14):1049-55. doi: 10.1038/gt.2008.32. Epub 2008 Mar 13. Erratum in: Gene Ther. 2011 Dec;18(12):1179. Gene Ther. 2008 Jul;15(14):1073. Glushakova, L G [added].

2.

Human blue-opsin promoter preferentially targets reporter gene expression to rat s-cone photoreceptors.

Glushakova LG, Timmers AM, Pang J, Teusner JT, Hauswirth WW.

Invest Ophthalmol Vis Sci. 2006 Aug;47(8):3505-13.

PMID:
16877422
3.

Cone-specific expression using a human red opsin promoter in recombinant AAV.

Li Q, Timmers AM, Guy J, Pang J, Hauswirth WW.

Vision Res. 2008 Feb;48(3):332-8. Epub 2007 Oct 1.

4.

Does recombinant adeno-associated virus-vectored proximal region of mouse rhodopsin promoter support only rod-type specific expression in vivo?

Glushakova LG, Timmers AM, Issa TM, Cortez NG, Pang J, Teusner JT, Hauswirth WW.

Mol Vis. 2006 Apr 7;12:298-309.

5.

AAV-mediated expression targeting of rod and cone photoreceptors with a human rhodopsin kinase promoter.

Khani SC, Pawlyk BS, Bulgakov OV, Kasperek E, Young JE, Adamian M, Sun X, Smith AJ, Ali RR, Li T.

Invest Ophthalmol Vis Sci. 2007 Sep;48(9):3954-61.

PMID:
17724172
6.

Gene therapy rescues cone function in congenital achromatopsia.

Komáromy AM, Alexander JJ, Rowlan JS, Garcia MM, Chiodo VA, Kaya A, Tanaka JC, Acland GM, Hauswirth WW, Aguirre GD.

Hum Mol Genet. 2010 Jul 1;19(13):2581-93. doi: 10.1093/hmg/ddq136. Epub 2010 Apr 8. Erratum in: Hum Mol Genet. 2011 Dec 15;20(24):5024.

7.

Prospects for retinal cone-targeted gene therapy.

Alexander JJ, Hauswirth WW.

Drug News Perspect. 2008 Jun;21(5):267-71. doi: 10.1358/dnp.2008.21.5.1219012.

PMID:
18596991
8.

rAAV2/5 gene-targeting to rods:dose-dependent efficiency and complications associated with different promoters.

Beltran WA, Boye SL, Boye SE, Chiodo VA, Lewin AS, Hauswirth WW, Aguirre GD.

Gene Ther. 2010 Sep;17(9):1162-74. doi: 10.1038/gt.2010.56. Epub 2010 Apr 29.

9.

The human rhodopsin kinase promoter in an AAV5 vector confers rod- and cone-specific expression in the primate retina.

Boye SE, Alexander JJ, Boye SL, Witherspoon CD, Sandefer KJ, Conlon TJ, Erger K, Sun J, Ryals R, Chiodo VA, Clark ME, Girkin CA, Hauswirth WW, Gamlin PD.

Hum Gene Ther. 2012 Oct;23(10):1101-15. doi: 10.1089/hum.2012.125. Epub 2012 Sep 20.

10.

Longitudinal evaluation of expression of virally delivered transgenes in gerbil cone photoreceptors.

Mauck MC, Mancuso K, Kuchenbecker JA, Connor TB, Hauswirth WW, Neitz J, Neitz M.

Vis Neurosci. 2008 May-Jun;25(3):273-82. doi: 10.1017/S0952523808080577.

11.

Retinal cone photoreceptors of the deer mouse Peromyscus maniculatus: development, topography, opsin expression and spectral tuning.

Arbogast P, Glösmann M, Peichl L.

PLoS One. 2013 Nov 15;8(11):e80910. doi: 10.1371/journal.pone.0080910. eCollection 2013.

12.
13.

Differential targeting of feline photoreceptors by recombinant adeno-associated viral vectors: implications for preclinical gene therapy trials.

Minella AL, Mowat FM, Willett KL, Sledge D, Bartoe JT, Bennett J, Petersen-Jones SM.

Gene Ther. 2014 Oct;21(10):913-20. doi: 10.1038/gt.2014.65. Epub 2014 Jul 24.

14.
15.

Stable rAAV-mediated transduction of rod and cone photoreceptors in the canine retina.

Bainbridge JW, Mistry A, Schlichtenbrede FC, Smith A, Broderick C, De Alwis M, Georgiadis A, Taylor PM, Squires M, Sethi C, Charteris D, Thrasher AJ, Sargan D, Ali RR.

Gene Ther. 2003 Aug;10(16):1336-44.

PMID:
12883530
16.

The role of opsin expression and apoptosis in determination of cone types in human retina.

Cornish EE, Xiao M, Yang Z, Provis JM, Hendrickson AE.

Exp Eye Res. 2004 Jun;78(6):1143-54.

PMID:
15109921
17.

Long-term restoration of rod and cone vision by single dose rAAV-mediated gene transfer to the retina in a canine model of childhood blindness.

Acland GM, Aguirre GD, Bennett J, Aleman TS, Cideciyan AV, Bennicelli J, Dejneka NS, Pearce-Kelling SE, Maguire AM, Palczewski K, Hauswirth WW, Jacobson SG.

Mol Ther. 2005 Dec;12(6):1072-82. Epub 2005 Oct 14.

18.

A 221-bp fragment of the mouse opsin promoter directs expression specifically to the rod photoreceptors of transgenic mice.

Quiambao AB, Peachey NS, Mangini NJ, Röhlich P, Hollyfield JG, al-Ubaidi MR.

Vis Neurosci. 1997 Jul-Aug;14(4):617-25.

PMID:
9278991
19.

AAV-mediated photoreceptor transduction of the pig cone-enriched retina.

Mussolino C, della Corte M, Rossi S, Viola F, Di Vicino U, Marrocco E, Neglia S, Doria M, Testa F, Giovannoni R, Crasta M, Giunti M, Villani E, Lavitrano M, Bacci ML, Ratiglia R, Simonelli F, Auricchio A, Surace EM.

Gene Ther. 2011 Jul;18(7):637-45. doi: 10.1038/gt.2011.3. Epub 2011 Mar 17.

20.

The human blue opsin promoter directs transgene expression in short-wave cones and bipolar cells in the mouse retina.

Chen J, Tucker CL, Woodford B, Szél A, Lem J, Gianella-Borradori A, Simon MI, Bogenmann E.

Proc Natl Acad Sci U S A. 1994 Mar 29;91(7):2611-5.

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