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Items: 1 to 20 of 86


Structure and mechanism of IFN-gamma antagonism by an orthopoxvirus IFN-gamma-binding protein.

Nuara AA, Walter LJ, Logsdon NJ, Yoon SI, Jones BC, Schriewer JM, Buller RM, Walter MR.

Proc Natl Acad Sci U S A. 2008 Feb 12;105(6):1861-6. doi: 10.1073/pnas.0705753105. Epub 2008 Feb 5.


Poxvirus-encoded gamma interferon binding protein dampens the host immune response to infection.

Sakala IG, Chaudhri G, Buller RM, Nuara AA, Bai H, Chen N, Karupiah G.

J Virol. 2007 Apr;81(7):3346-53. Epub 2007 Jan 17.


The unique C termini of orthopoxvirus gamma interferon binding proteins are essential for ligand binding.

Nuara AA, Bai H, Chen N, Buller RM, Walter MR.

J Virol. 2006 Nov;80(21):10675-82. Epub 2006 Aug 23.


Biosynthesis of the IFN-gamma binding protein of ectromelia virus, the causative agent of mousepox.

Bai H, Buller RM, Chen N, Green M, Nuara AA.

Virology. 2005 Mar 30;334(1):41-50.


Deficiency in Th2 cytokine responses exacerbate orthopoxvirus infection.

Sakala IG, Chaudhri G, Eldi P, Buller RM, Karupiah G.

PLoS One. 2015 Mar 9;10(3):e0118685. doi: 10.1371/journal.pone.0118685. eCollection 2015.


Inhibition of interferons by ectromelia virus.

Smith VP, Alcami A.

J Virol. 2002 Feb;76(3):1124-34.


An ectromelia virus profilin homolog interacts with cellular tropomyosin and viral A-type inclusion protein.

Butler-Cole C, Wagner MJ, Da Silva M, Brown GD, Burke RD, Upton C.

Virol J. 2007 Jul 24;4:76.


The orthopoxvirus type I IFN binding protein is essential for virulence and an effective target for vaccination.

Xu RH, Cohen M, Tang Y, Lazear E, Whitbeck JC, Eisenberg RJ, Cohen GH, Sigal LJ.

J Exp Med. 2008 Apr 14;205(4):981-92. doi: 10.1084/jem.20071854. Epub 2008 Apr 7.


Interferon function is not required for recovery from a secondary poxvirus infection.

Panchanathan V, Chaudhri G, Karupiah G.

Proc Natl Acad Sci U S A. 2005 Sep 6;102(36):12921-6. Epub 2005 Aug 25.


Structural basis for antagonism of human interleukin 18 by poxvirus interleukin 18-binding protein.

Krumm B, Meng X, Li Y, Xiang Y, Deng J.

Proc Natl Acad Sci U S A. 2008 Dec 30;105(52):20711-5. doi: 10.1073/pnas.0809086106. Epub 2008 Dec 22.


Loss of cytoskeletal transport during egress critically attenuates ectromelia virus infection in vivo.

Lynn H, Horsington J, Ter LK, Han S, Chew YL, Diefenbach RJ, Way M, Chaudhri G, Karupiah G, Newsome TP.

J Virol. 2012 Jul;86(13):7427-43. doi: 10.1128/JVI.06636-11. Epub 2012 Apr 24.


N1L is an ectromelia virus virulence factor and essential for in vivo spread upon respiratory infection.

Gratz MS, Suezer Y, Kremer M, Volz A, Majzoub M, Hanschmann KM, Kalinke U, Schwantes A, Sutter G.

J Virol. 2011 Apr;85(7):3557-69. doi: 10.1128/JVI.01191-10. Epub 2011 Jan 26.


An interferon-gamma-binding protein of novel structure encoded by the fowlpox virus.

Puehler F, Schwarz H, Waidner B, Kalinowski J, Kaspers B, Bereswill S, Staeheli P.

J Biol Chem. 2003 Feb 28;278(9):6905-11. Epub 2002 Dec 13.


Interaction of orthopoxviruses with the cellular ubiquitin-ligase system.

Shchelkunov SN.

Virus Genes. 2010 Dec;41(3):309-18. doi: 10.1007/s11262-010-0519-y. Epub 2010 Aug 12. Review.


Observation of an unexpected third receptor molecule in the crystal structure of human interferon-gamma receptor complex.

Thiel DJ, le Du MH, Walter RL, D'Arcy A, Chène C, Fountoulakis M, Garotta G, Winkler FK, Ealick SE.

Structure. 2000 Sep 15;8(9):927-36.


Design, characterization, and structure of a biologically active single-chain mutant of human IFN-gamma.

Landar A, Curry B, Parker MH, DiGiacomo R, Indelicato SR, Nagabhushan TL, Rizzi G, Walter MR.

J Mol Biol. 2000 May 26;299(1):169-79.


Soluble interferon-gamma receptors encoded by poxviruses.

Alcamí A, Smith GL.

Comp Immunol Microbiol Infect Dis. 1996 Sep;19(4):305-17.

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