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Results: 1 to 20 of 214

1.

Reactive oxygen species regulate neutrophil recruitment and survival in pneumococcal pneumonia.

Marriott HM, Jackson LE, Wilkinson TS, Simpson AJ, Mitchell TJ, Buttle DJ, Cross SS, Ince PG, Hellewell PG, Whyte MK, Dockrell DH.

Am J Respir Crit Care Med. 2008 Apr 15;177(8):887-95. doi: 10.1164/rccm.200707-990OC. Epub 2008 Jan 17.

PMID:
18202350
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Genetic deficiency of NADPH oxidase does not diminish, but rather enhances, LPS-induced acute inflammatory responses in vivo.

Zhang WJ, Wei H, Frei B.

Free Radic Biol Med. 2009 Mar 15;46(6):791-8. doi: 10.1016/j.freeradbiomed.2008.12.003. Epub 2008 Dec 24.

PMID:
19124074
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Influenza infection suppresses NADPH oxidase-dependent phagocytic bacterial clearance and enhances susceptibility to secondary methicillin-resistant Staphylococcus aureus infection.

Sun K, Metzger DW.

J Immunol. 2014 Apr 1;192(7):3301-7. doi: 10.4049/jimmunol.1303049. Epub 2014 Feb 21.

PMID:
24563256
[PubMed - indexed for MEDLINE]
4.

Neither neutrophils nor reactive oxygen species contribute to tissue damage during Pneumocystis pneumonia in mice.

Swain SD, Wright TW, Degel PM, Gigliotti F, Harmsen AG.

Infect Immun. 2004 Oct;72(10):5722-32.

PMID:
15385471
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Role of NADPH oxidase in the mechanism of lung neutrophil sequestration and microvessel injury induced by Gram-negative sepsis: studies in p47phox-/- and gp91phox-/- mice.

Gao XP, Standiford TJ, Rahman A, Newstead M, Holland SM, Dinauer MC, Liu QH, Malik AB.

J Immunol. 2002 Apr 15;168(8):3974-82.

PMID:
11937554
[PubMed - indexed for MEDLINE]
Free Article
6.

NADPH oxidase-dependent reactive oxygen species mediate amplified TLR4 signaling and sepsis-induced mortality in Nrf2-deficient mice.

Kong X, Thimmulappa R, Kombairaju P, Biswal S.

J Immunol. 2010 Jul 1;185(1):569-77. doi: 10.4049/jimmunol.0902315. Epub 2010 May 28.

PMID:
20511556
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Decreased alveolar macrophage apoptosis is associated with increased pulmonary inflammation in a murine model of pneumococcal pneumonia.

Marriott HM, Hellewell PG, Cross SS, Ince PG, Whyte MK, Dockrell DH.

J Immunol. 2006 Nov 1;177(9):6480-8.

PMID:
17056580
[PubMed - indexed for MEDLINE]
Free Article
8.

Oxidative burst and neutrophil elastase contribute to clearance of Aspergillus fumigatus pneumonia in mice.

Prüfer S, Weber M, Stein P, Bosmann M, Stassen M, Kreft A, Schild H, Radsak MP.

Immunobiology. 2014 Feb;219(2):87-96. doi: 10.1016/j.imbio.2013.08.010. Epub 2013 Aug 30.

PMID:
24054721
[PubMed - indexed for MEDLINE]
9.

Genetic ablation of NADPH oxidase enhances susceptibility to cigarette smoke-induced lung inflammation and emphysema in mice.

Yao H, Edirisinghe I, Yang SR, Rajendrasozhan S, Kode A, Caito S, Adenuga D, Rahman I.

Am J Pathol. 2008 May;172(5):1222-37. doi: 10.2353/ajpath.2008.070765. Epub 2008 Apr 10.

PMID:
18403597
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Induction of gp91-phox, a component of the phagocyte NADPH oxidase, in microglial cells during central nervous system inflammation.

Green SP, Cairns B, Rae J, Errett-Baroncini C, Hongo JA, Erickson RW, Curnutte JT.

J Cereb Blood Flow Metab. 2001 Apr;21(4):374-84.

PMID:
11323523
[PubMed - indexed for MEDLINE]
Free Article
11.

Role of neutrophils and NADPH phagocyte oxidase in host defense against respiratory infection with virulent Francisella tularensis in mice.

KuoLee R, Harris G, Conlan JW, Chen W.

Microbes Infect. 2011 May;13(5):447-56. doi: 10.1016/j.micinf.2011.01.010. Epub 2011 Jan 26.

PMID:
21277990
[PubMed - indexed for MEDLINE]
12.

Bioluminescence imaging of NADPH oxidase activity in different animal models.

Han W, Li H, Segal BH, Blackwell TS.

J Vis Exp. 2012 Oct 22;(68). pii: 3925. doi: 10.3791/3925.

PMID:
23117583
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Genetic ablation of phagocytic NADPH oxidase in mice limits TNFα-induced inflammation in the lungs but not other tissues.

Zhang WJ, Wei H, Tien YT, Frei B.

Free Radic Biol Med. 2011 Jun 1;50(11):1517-25. doi: 10.1016/j.freeradbiomed.2011.02.027. Epub 2011 Mar 2.

PMID:
21376114
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

NADPH phagocyte oxidase knockout mice control Trypanosoma cruzi proliferation, but develop circulatory collapse and succumb to infection.

Santiago HC, Gonzalez Lombana CZ, Macedo JP, Utsch L, Tafuri WL, Campagnole-Santos MJ, Alves RO, Alves-Filho JC, Romanha AJ, Cunha FQ, Teixeira MM, Radi R, Vieira LQ.

PLoS Negl Trop Dis. 2012;6(2):e1492. doi: 10.1371/journal.pntd.0001492. Epub 2012 Feb 14.

PMID:
22348160
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Deficiency of nicotinamide adenine dinucleotide phosphate, reduced form oxidase enhances hepatocellular injury but attenuates fibrosis after chronic carbon tetrachloride administration.

Aram G, Potter JJ, Liu X, Wang L, Torbenson MS, Mezey E.

Hepatology. 2009 Mar;49(3):911-9. doi: 10.1002/hep.22708.

PMID:
19072832
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

O2 sensing is preserved in mice lacking the gp91 phox subunit of NADPH oxidase.

Archer SL, Reeve HL, Michelakis E, Puttagunta L, Waite R, Nelson DP, Dinauer MC, Weir EK.

Proc Natl Acad Sci U S A. 1999 Jul 6;96(14):7944-9.

PMID:
10393927
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

NADPH oxidase limits lipopolysaccharide-induced lung inflammation and injury in mice through reduction-oxidation regulation of NF-κB activity.

Han W, Li H, Cai J, Gleaves LA, Polosukhin VV, Segal BH, Yull FE, Blackwell TS.

J Immunol. 2013 May 1;190(9):4786-94. doi: 10.4049/jimmunol.1201809. Epub 2013 Mar 25.

PMID:
23530143
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

NADPH oxidase and Nrf2 regulate gastric aspiration-induced inflammation and acute lung injury.

Davidson BA, Vethanayagam RR, Grimm MJ, Mullan BA, Raghavendran K, Blackwell TS, Freeman ML, Ayyasamy V, Singh KK, Sporn MB, Itagaki K, Hauser CJ, Knight PR, Segal BH.

J Immunol. 2013 Feb 15;190(4):1714-24. doi: 10.4049/jimmunol.1202410. Epub 2013 Jan 7.

PMID:
23296708
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Early neutrophil recruitment and aggregation in the murine lung inhibit germination of Aspergillus fumigatus Conidia.

Bonnett CR, Cornish EJ, Harmsen AG, Burritt JB.

Infect Immun. 2006 Dec;74(12):6528-39. Epub 2006 Aug 18.

PMID:
16920786
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

NOX2 protects against prolonged inflammation, lung injury, and mortality following systemic insults.

Whitmore LC, Hilkin BM, Goss KL, Wahle EM, Colaizy TT, Boggiatto PM, Varga SM, Miller FJ, Moreland JG.

J Innate Immun. 2013;5(6):565-80. doi: 10.1159/000347212. Epub 2013 Apr 27.

PMID:
23635512
[PubMed - indexed for MEDLINE]

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