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Items: 1 to 20 of 169

1.

Specific physiological roles for signal transducer and activator of transcription 3 in leptin receptor-expressing neurons.

Piper ML, Unger EK, Myers MG Jr, Xu AW.

Mol Endocrinol. 2008 Mar;22(3):751-9. Epub 2007 Dec 20.

2.

Over-expression of leptin receptors in hypothalamic POMC neurons increases susceptibility to diet-induced obesity.

Gamber KM, Huo L, Ha S, Hairston JE, Greeley S, Bjørbæk C.

PLoS One. 2012;7(1):e30485. doi: 10.1371/journal.pone.0030485. Epub 2012 Jan 20.

3.

Signal transducer and activator of transcription-3 is required in hypothalamic agouti-related protein/neuropeptide Y neurons for normal energy homeostasis.

Gong L, Yao F, Hockman K, Heng HH, Morton GJ, Takeda K, Akira S, Low MJ, Rubinstein M, MacKenzie RG.

Endocrinology. 2008 Jul;149(7):3346-54. doi: 10.1210/en.2007-0945. Epub 2008 Apr 10.

4.

Leptin receptor neurons in the mouse hypothalamus are colocalized with the neuropeptide galanin and mediate anorexigenic leptin action.

Laque A, Zhang Y, Gettys S, Nguyen TA, Bui K, Morrison CD, Münzberg H.

Am J Physiol Endocrinol Metab. 2013 May 1;304(9):E999-1011. doi: 10.1152/ajpendo.00643.2012. Epub 2013 Mar 12.

5.

Somato-dendritic localization and signaling by leptin receptors in hypothalamic POMC and AgRP neurons.

Ha S, Baver S, Huo L, Gata A, Hairston J, Huntoon N, Li W, Zhang T, Benecchi EJ, Ericsson M, Hentges ST, Bjørbæk C.

PLoS One. 2013 Oct 29;8(10):e77622. doi: 10.1371/journal.pone.0077622. eCollection 2013. Erratum in: PLoS One. 2013;8(12). doi:10.1371/annotation/a3ef8765-266f-4e4b-8370-264d6f6f301e.

6.

Leptin receptor signaling and the regulation of mammalian physiology.

Villanueva EC, Myers MG Jr.

Int J Obes (Lond). 2008 Dec;32 Suppl 7:S8-12. doi: 10.1038/ijo.2008.232. Review.

7.

Neither signal transducer and activator of transcription 3 (STAT3) or STAT5 signaling pathways are required for leptin's effects on fertility in mice.

Singireddy AV, Inglis MA, Zuure WA, Kim JS, Anderson GM.

Endocrinology. 2013 Jul;154(7):2434-45. doi: 10.1210/en.2013-1109. Epub 2013 May 21.

PMID:
23696567
8.

Enhanced Stat3 activation in POMC neurons provokes negative feedback inhibition of leptin and insulin signaling in obesity.

Ernst MB, Wunderlich CM, Hess S, Paehler M, Mesaros A, Koralov SB, Kleinridders A, Husch A, Münzberg H, Hampel B, Alber J, Kloppenburg P, Brüning JC, Wunderlich FT.

J Neurosci. 2009 Sep 16;29(37):11582-93. doi: 10.1523/JNEUROSCI.5712-08.2009.

10.

Involvement of leptin receptor long isoform (LepRb)-STAT3 signaling pathway in brain fat mass- and obesity-associated (FTO) downregulation during energy restriction.

Wang P, Yang FJ, Du H, Guan YF, Xu TY, Xu XW, Su DF, Miao CY.

Mol Med. 2011 May-Jun;17(5-6):523-32. doi: 10.2119/molmed.2010.00134. Epub 2011 Jan 21.

11.

Molecular and neural mediators of leptin action.

Robertson SA, Leinninger GM, Myers MG Jr.

Physiol Behav. 2008 Aug 6;94(5):637-42. doi: 10.1016/j.physbeh.2008.04.005. Epub 2008 Apr 13. Review.

12.

Leptin action through hypothalamic nitric oxide synthase-1-expressing neurons controls energy balance.

Leshan RL, Greenwald-Yarnell M, Patterson CM, Gonzalez IE, Myers MG Jr.

Nat Med. 2012 May;18(5):820-3. doi: 10.1038/nm.2724.

13.

Rho-kinase regulates energy balance by targeting hypothalamic leptin receptor signaling.

Huang H, Kong D, Byun KH, Ye C, Koda S, Lee DH, Oh BC, Lee SW, Lee B, Zabolotny JM, Kim MS, Bjørbæk C, Lowell BB, Kim YB.

Nat Neurosci. 2012 Oct;15(10):1391-8. doi: 10.1038/nn.3207. Epub 2012 Sep 2.

14.

Functional potentiation of leptin-signal transducer and activator of transcription 3 signaling by the androgen receptor.

Fan W, Yanase T, Nishi Y, Chiba S, Okabe T, Nomura M, Yoshimatsu H, Kato S, Takayanagi R, Nawata H.

Endocrinology. 2008 Dec;149(12):6028-36. doi: 10.1210/en.2008-0431. Epub 2008 Aug 14.

PMID:
18703637
15.

Neurochemical characterization of body weight-regulating leptin receptor neurons in the nucleus of the solitary tract.

Garfield AS, Patterson C, Skora S, Gribble FM, Reimann F, Evans ML, Myers MG Jr, Heisler LK.

Endocrinology. 2012 Oct;153(10):4600-7. Epub 2012 Aug 6.

16.

Phosphodiesterase-3B is expressed in proopiomelanocortin and neuropeptide Y neurons in the mouse hypothalamus.

Sahu M, Litvin DG, Sahu A.

Neurosci Lett. 2011 Nov 14;505(2):93-7. doi: 10.1016/j.neulet.2011.09.068. Epub 2011 Oct 6.

17.
18.

Role of signal transducer and activator of transcription 3 in regulation of hypothalamic proopiomelanocortin gene expression by leptin.

Münzberg H, Huo L, Nillni EA, Hollenberg AN, Bjørbaek C.

Endocrinology. 2003 May;144(5):2121-31.

PMID:
12697721
19.

Complete rescue of obesity, diabetes, and infertility in db/db mice by neuron-specific LEPR-B transgenes.

de Luca C, Kowalski TJ, Zhang Y, Elmquist JK, Lee C, Kilimann MW, Ludwig T, Liu SM, Chua SC Jr.

J Clin Invest. 2005 Dec;115(12):3484-93. Epub 2005 Nov 10.

20.

Insufficiency of Janus kinase 2-autonomous leptin receptor signals for most physiologic leptin actions.

Robertson S, Ishida-Takahashi R, Tawara I, Hu J, Patterson CM, Jones JC, Kulkarni RN, Myers MG Jr.

Diabetes. 2010 Apr;59(4):782-90. doi: 10.2337/db09-1556. Epub 2010 Jan 12.

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