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Results: 1 to 20 of 169

1.

Coronavirus escape from heptad repeat 2 (HR2)-derived peptide entry inhibition as a result of mutations in the HR1 domain of the spike fusion protein.

Bosch BJ, Rossen JW, Bartelink W, Zuurveen SJ, de Haan CA, Duquerroy S, Boucher CA, Rottier PJ.

J Virol. 2008 Mar;82(5):2580-5. Epub 2007 Dec 12.

PMID:
18077706
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

The coronavirus spike protein is a class I virus fusion protein: structural and functional characterization of the fusion core complex.

Bosch BJ, van der Zee R, de Haan CA, Rottier PJ.

J Virol. 2003 Aug;77(16):8801-11.

PMID:
12885899
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Severe acute respiratory syndrome coronavirus (SARS-CoV) infection inhibition using spike protein heptad repeat-derived peptides.

Bosch BJ, Martina BE, Van Der Zee R, Lepault J, Haijema BJ, Versluis C, Heck AJ, De Groot R, Osterhaus AD, Rottier PJ.

Proc Natl Acad Sci U S A. 2004 Jun 1;101(22):8455-60. Epub 2004 May 18.

PMID:
15150417
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Characterization of the heptad repeat regions, HR1 and HR2, and design of a fusion core structure model of the spike protein from severe acute respiratory syndrome (SARS) coronavirus.

Xu Y, Zhu J, Liu Y, Lou Z, Yuan F, Liu Y, Cole DK, Ni L, Su N, Qin L, Li X, Bai Z, Bell JI, Pang H, Tien P, Gao GF, Rao Z.

Biochemistry. 2004 Nov 9;43(44):14064-71.

PMID:
15518555
[PubMed - indexed for MEDLINE]
5.

Interaction between heptad repeat 1 and 2 regions in spike protein of SARS-associated coronavirus: implications for virus fusogenic mechanism and identification of fusion inhibitors.

Liu S, Xiao G, Chen Y, He Y, Niu J, Escalante CR, Xiong H, Farmar J, Debnath AK, Tien P, Jiang S.

Lancet. 2004 Mar 20;363(9413):938-47.

PMID:
15043961
[PubMed - indexed for MEDLINE]
6.

Structural basis for coronavirus-mediated membrane fusion. Crystal structure of mouse hepatitis virus spike protein fusion core.

Xu Y, Liu Y, Lou Z, Qin L, Li X, Bai Z, Pang H, Tien P, Gao GF, Rao Z.

J Biol Chem. 2004 Jul 16;279(29):30514-22. Epub 2004 Apr 27.

PMID:
15123674
[PubMed - indexed for MEDLINE]
Free Article
7.

Solution structure of the severe acute respiratory syndrome-coronavirus heptad repeat 2 domain in the prefusion state.

Hakansson-McReynolds S, Jiang S, Rong L, Caffrey M.

J Biol Chem. 2006 Apr 28;281(17):11965-71. Epub 2006 Feb 28.

PMID:
16507566
[PubMed - indexed for MEDLINE]
Free Article
8.

Amino acid substitutions within the heptad repeat domain 1 of murine coronavirus spike protein restrict viral antigen spread in the central nervous system.

Tsai JC, de Groot L, Pinon JD, Iacono KT, Phillips JJ, Seo SH, Lavi E, Weiss SR.

Virology. 2003 Aug 1;312(2):369-80.

PMID:
12919742
[PubMed - indexed for MEDLINE]
Free Article
9.

Crystal structure of severe acute respiratory syndrome coronavirus spike protein fusion core.

Xu Y, Lou Z, Liu Y, Pang H, Tien P, Gao GF, Rao Z.

J Biol Chem. 2004 Nov 19;279(47):49414-9. Epub 2004 Sep 1.

PMID:
15345712
[PubMed - indexed for MEDLINE]
Free Article
10.

Roles in cell-to-cell fusion of two conserved hydrophobic regions in the murine coronavirus spike protein.

Luo Z, Weiss SR.

Virology. 1998 May 10;244(2):483-94.

PMID:
9601516
[PubMed - indexed for MEDLINE]
Free Article
11.

Identification of a minimal peptide derived from heptad repeat (HR) 2 of spike protein of SARS-CoV and combination of HR1-derived peptides as fusion inhibitors.

Liu IJ, Kao CL, Hsieh SC, Wey MT, Kan LS, Wang WK.

Antiviral Res. 2009 Jan;81(1):82-7. doi: 10.1016/j.antiviral.2008.10.001. Epub 2008 Nov 5.

PMID:
18983873
[PubMed - indexed for MEDLINE]
12.

Suppression of SARS-CoV entry by peptides corresponding to heptad regions on spike glycoprotein.

Yuan K, Yi L, Chen J, Qu X, Qing T, Rao X, Jiang P, Hu J, Xiong Z, Nie Y, Shi X, Wang W, Ling C, Yin X, Fan K, Lai L, Ding M, Deng H.

Biochem Biophys Res Commun. 2004 Jul 2;319(3):746-52.

PMID:
15184046
[PubMed - indexed for MEDLINE]
13.

Core structure of S2 from the human coronavirus NL63 spike glycoprotein.

Zheng Q, Deng Y, Liu J, van der Hoek L, Berkhout B, Lu M.

Biochemistry. 2006 Dec 26;45(51):15205-15. Epub 2006 Dec 1.

PMID:
17176042
[PubMed - indexed for MEDLINE]
14.

Structure of a proteolytically resistant core from the severe acute respiratory syndrome coronavirus S2 fusion protein.

Supekar VM, Bruckmann C, Ingallinella P, Bianchi E, Pessi A, CarfĂ­ A.

Proc Natl Acad Sci U S A. 2004 Dec 28;101(52):17958-63. Epub 2004 Dec 16.

PMID:
15604146
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Construct design, biophysical, and biochemical characterization of the fusion core from mouse hepatitis virus (a coronavirus) spike protein.

Xu Y, Cole DK, Lou Z, Liu Y, Qin L, Li X, Bai Z, Yuan F, Rao Z, Gao GF.

Protein Expr Purif. 2004 Nov;38(1):116-22.

PMID:
15477089
[PubMed - indexed for MEDLINE]
16.

Following the rule: formation of the 6-helix bundle of the fusion core from severe acute respiratory syndrome coronavirus spike protein and identification of potent peptide inhibitors.

Zhu J, Xiao G, Xu Y, Yuan F, Zheng C, Liu Y, Yan H, Cole DK, Bell JI, Rao Z, Tien P, Gao GF.

Biochem Biophys Res Commun. 2004 Jun 18;319(1):283-8.

PMID:
15158473
[PubMed - indexed for MEDLINE]
17.

Structures and polymorphic interactions of two heptad-repeat regions of the SARS virus S2 protein.

Deng Y, Liu J, Zheng Q, Yong W, Lu M.

Structure. 2006 May;14(5):889-99.

PMID:
16698550
[PubMed - indexed for MEDLINE]
Free Article
18.

Identification and characterization of the putative fusion peptide of the severe acute respiratory syndrome-associated coronavirus spike protein.

Sainz B Jr, Rausch JM, Gallaher WR, Garry RF, Wimley WC.

J Virol. 2005 Jun;79(11):7195-206.

PMID:
15890958
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Design of recombinant protein-based SARS-CoV entry inhibitors targeting the heptad-repeat regions of the spike protein S2 domain.

Ni L, Zhu J, Zhang J, Yan M, Gao GF, Tien P.

Biochem Biophys Res Commun. 2005 Apr 29;330(1):39-45.

PMID:
15781229
[PubMed - indexed for MEDLINE]
20.

Heptad repeat 2-based peptides inhibit avian sarcoma and leukosis virus subgroup a infection and identify a fusion intermediate.

Netter RC, Amberg SM, Balliet JW, Biscone MJ, Vermeulen A, Earp LJ, White JM, Bates P.

J Virol. 2004 Dec;78(24):13430-9.

PMID:
15564453
[PubMed - indexed for MEDLINE]
Free PMC Article

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