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Results: 1 to 20 of 144

1.

The Na+/I symporter (NIS) mediates electroneutral active transport of the environmental pollutant perchlorate.

Dohán O, Portulano C, Basquin C, Reyna-Neyra A, Amzel LM, Carrasco N.

Proc Natl Acad Sci U S A. 2007 Dec 18;104(51):20250-5. Epub 2007 Dec 11.

PMID:
18077370
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Use of the thyrocyte sodium iodide symporter as the basis for a perchlorate cell-based assay.

MacAllister IE, Jakoby MG 4th, Geryk B, Schneider RL, Cropek DM.

Analyst. 2009 Feb;134(2):320-4. doi: 10.1039/b802710b. Epub 2008 Oct 30.

PMID:
19173056
[PubMed - indexed for MEDLINE]
3.

Perchlorate transport and inhibition of the sodium iodide symporter measured with the yellow fluorescent protein variant YFP-H148Q/I152L.

Cianchetta S, di Bernardo J, Romeo G, Rhoden KJ.

Toxicol Appl Pharmacol. 2010 Mar 15;243(3):372-80. doi: 10.1016/j.taap.2009.12.004. Epub 2009 Dec 18.

PMID:
20005887
[PubMed - indexed for MEDLINE]
4.

Kinetics of perrhenate uptake and comparative biodistribution of perrhenate, pertechnetate, and iodide by NaI symporter-expressing tissues in vivo.

Zuckier LS, Dohan O, Li Y, Chang CJ, Carrasco N, Dadachova E.

J Nucl Med. 2004 Mar;45(3):500-7. Erratum in: J Nucl Med. 2004 Apr;45(4):558. Dohan, Orshi [corrected to Dohan, Orsolya].

PMID:
15001694
[PubMed - indexed for MEDLINE]
Free Article
5.

Perchlorate versus other environmental sodium/iodide symporter inhibitors: potential thyroid-related health effects.

De Groef B, Decallonne BR, Van der Geyten S, Darras VM, Bouillon R.

Eur J Endocrinol. 2006 Jul;155(1):17-25. Review.

PMID:
16793945
[PubMed - indexed for MEDLINE]
Free Article
6.

Intracellular anion fluorescence assay for sodium/iodide symporter substrates.

Di Bernardo J, Iosco C, Rhoden KJ.

Anal Biochem. 2011 Aug 1;415(1):32-8. doi: 10.1016/j.ab.2011.04.017. Epub 2011 Apr 20.

PMID:
21545783
[PubMed - indexed for MEDLINE]
7.

Relative potencies and additivity of perchlorate, thiocyanate, nitrate, and iodide on the inhibition of radioactive iodide uptake by the human sodium iodide symporter.

Tonacchera M, Pinchera A, Dimida A, Ferrarini E, Agretti P, Vitti P, Santini F, Crump K, Gibbs J.

Thyroid. 2004 Dec;14(12):1012-9.

PMID:
15650353
[PubMed - indexed for MEDLINE]
8.

Differences in the electrophysiological response to I- and the inhibitory anions SCN- and ClO-4, studied in FRTL-5 cells.

Yoshida A, Sasaki N, Mori A, Taniguchi S, Ueta Y, Hattori K, Tanaka Y, Igawa O, Tsuboi M, Sugawa H, Sato R, Hisatome I, Shigemasa C, Grollman EF, Kosugi S.

Biochim Biophys Acta. 1998 Nov 11;1414(1-2):231-7.

PMID:
9804961
[PubMed - indexed for MEDLINE]
9.

Thyroid Na+/I- symporter. Mechanism, stoichiometry, and specificity.

Eskandari S, Loo DD, Dai G, Levy O, Wright EM, Carrasco N.

J Biol Chem. 1997 Oct 24;272(43):27230-8.

PMID:
9341168
[PubMed - indexed for MEDLINE]
Free Article
10.

The Na+/I- symporter mediates active iodide uptake in the intestine.

Nicola JP, Basquin C, Portulano C, Reyna-Neyra A, Paroder M, Carrasco N.

Am J Physiol Cell Physiol. 2009 Apr;296(4):C654-62. doi: 10.1152/ajpcell.00509.2008. Epub 2008 Dec 3.

PMID:
19052257
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Predicting neonatal perchlorate dose and inhibition of iodide uptake in the rat during lactation using physiologically-based pharmacokinetic modeling.

Clewell RA, Merrill EA, Yu KO, Mahle DA, Sterner TR, Fisher JW, Gearhart JM.

Toxicol Sci. 2003 Aug;74(2):416-36. Epub 2003 Jun 12.

PMID:
12805655
[PubMed - indexed for MEDLINE]
Free Article
12.

Amino acid residues in transmembrane segment IX of the Na+/I- symporter play a role in its Na+ dependence and are critical for transport activity.

De la Vieja A, Reed MD, Ginter CS, Carrasco N.

J Biol Chem. 2007 Aug 31;282(35):25290-8. Epub 2007 Jul 2.

PMID:
17606623
[PubMed - indexed for MEDLINE]
Free Article
13.

Anion selectivity by the sodium iodide symporter.

Van Sande J, Massart C, Beauwens R, Schoutens A, Costagliola S, Dumont JE, Wolff J.

Endocrinology. 2003 Jan;144(1):247-52.

PMID:
12488351
[PubMed - indexed for MEDLINE]
14.

Mechanism of anion selectivity and stoichiometry of the Na+/I- symporter (NIS).

Paroder-Belenitsky M, Maestas MJ, Dohán O, Nicola JP, Reyna-Neyra A, Follenzi A, Dadachova E, Eskandari S, Amzel LM, Carrasco N.

Proc Natl Acad Sci U S A. 2011 Nov 1;108(44):17933-8. doi: 10.1073/pnas.1108278108. Epub 2011 Oct 19.

PMID:
22011571
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Advances in Na(+)/I(-) symporter (NIS) research in the thyroid and beyond.

Dohán O, Carrasco N.

Mol Cell Endocrinol. 2003 Dec 31;213(1):59-70. Review.

PMID:
15062574
[PubMed - indexed for MEDLINE]
16.

Cell-based imaging of sodium iodide symporter activity with the yellow fluorescent protein variant YFP-H148Q/I152L.

Rhoden KJ, Cianchetta S, Stivani V, Portulano C, Galietta LJ, Romeo G.

Am J Physiol Cell Physiol. 2007 Feb;292(2):C814-23. Epub 2006 Sep 20.

PMID:
16987991
[PubMed - indexed for MEDLINE]
Free Article
17.

The Na/I symporter (NIS): imaging and therapeutic applications.

Dadachova E, Carrasco N.

Semin Nucl Med. 2004 Jan;34(1):23-31. Review.

PMID:
14735456
[PubMed - indexed for MEDLINE]
18.

The Na+/I- symporter mediates iodide uptake in breast cancer metastases and can be selectively down-regulated in the thyroid.

Wapnir IL, Goris M, Yudd A, Dohan O, Adelman D, Nowels K, Carrasco N.

Clin Cancer Res. 2004 Jul 1;10(13):4294-302. Erratum in: Clin Cancer Res. 2004 Nov 15;10(22):7787. Dosage error in article text.

PMID:
15240514
[PubMed - indexed for MEDLINE]
Free Article
19.

PBPK model for radioactive iodide and perchlorate kinetics and perchlorate-induced inhibition of iodide uptake in humans.

Merrill EA, Clewell RA, Robinson PJ, Jarabek AM, Gearhart JM, Sterner TR, Fisher JW.

Toxicol Sci. 2005 Jan;83(1):25-43. Epub 2004 Oct 27.

PMID:
15509666
[PubMed - indexed for MEDLINE]
Free Article
20.

Biology and clinical application of the NIS gene.

Elisei R, Vivaldi A, Pacini F.

Tumori. 2003 Sep-Oct;89(5):523-8. Review.

PMID:
14870777
[PubMed - indexed for MEDLINE]
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