Display Settings:

Format
Items per page
Sort by

Send to:

Choose Destination

Results: 1 to 20 of 78

1.

The E3 ubiquitin ligase EDD regulates S-phase and G(2)/M DNA damage checkpoints.

Munoz MA, Saunders DN, Henderson MJ, Clancy JL, Russell AJ, Lehrbach G, Musgrove EA, Watts CK, Sutherland RL.

Cell Cycle. 2007 Dec 15;6(24):3070-7. Epub 2007 Sep 7.

PMID:
18073532
[PubMed - indexed for MEDLINE]
Free Article
2.

EDD mediates DNA damage-induced activation of CHK2.

Henderson MJ, Munoz MA, Saunders DN, Clancy JL, Russell AJ, Williams B, Pappin D, Khanna KK, Jackson SP, Sutherland RL, Watts CK.

J Biol Chem. 2006 Dec 29;281(52):39990-40000. Epub 2006 Oct 30.

PMID:
17074762
[PubMed - indexed for MEDLINE]
Free Article
4.

Defective Mre11-dependent activation of Chk2 by ataxia telangiectasia mutated in colorectal carcinoma cells in response to replication-dependent DNA double strand breaks.

Takemura H, Rao VA, Sordet O, Furuta T, Miao ZH, Meng L, Zhang H, Pommier Y.

J Biol Chem. 2006 Oct 13;281(41):30814-23. Epub 2006 Aug 10.

PMID:
16905549
[PubMed - indexed for MEDLINE]
Free Article
5.

The cell cycle checkpoint kinase Chk2 is a negative regulator of mitotic catastrophe.

Castedo M, Perfettini JL, Roumier T, Yakushijin K, Horne D, Medema R, Kroemer G.

Oncogene. 2004 May 27;23(25):4353-61.

PMID:
15048074
[PubMed - indexed for MEDLINE]
6.

no poles encodes a predicted E3 ubiquitin ligase required for early embryonic development of Drosophila.

Merkle JA, Rickmyre JL, Garg A, Loggins EB, Jodoin JN, Lee E, Wu LP, Lee LA.

Development. 2009 Feb;136(3):449-59. doi: 10.1242/dev.027599.

PMID:
19141674
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Sulforaphane-induced G2/M phase cell cycle arrest involves checkpoint kinase 2-mediated phosphorylation of cell division cycle 25C.

Singh SV, Herman-Antosiewicz A, Singh AV, Lew KL, Srivastava SK, Kamath R, Brown KD, Zhang L, Baskaran R.

J Biol Chem. 2004 Jun 11;279(24):25813-22. Epub 2004 Apr 8.

PMID:
15073169
[PubMed - indexed for MEDLINE]
Free Article
8.

5-fluoro-2'-deoxyuridine-induced cdc25A accumulation correlates with premature mitotic entry and clonogenic death in human colon cancer cells.

Parsels LA, Parsels JD, Tai DC, Coughlin DJ, Maybaum J.

Cancer Res. 2004 Sep 15;64(18):6588-94.

PMID:
15374972
[PubMed - indexed for MEDLINE]
Free Article
9.

Ataxia-telangiectasia-mutated (ATM) and NBS1-dependent phosphorylation of Chk1 on Ser-317 in response to ionizing radiation.

Gatei M, Sloper K, Sorensen C, Syljuäsen R, Falck J, Hobson K, Savage K, Lukas J, Zhou BB, Bartek J, Khanna KK.

J Biol Chem. 2003 Apr 25;278(17):14806-11. Epub 2003 Feb 14.

PMID:
12588868
[PubMed - indexed for MEDLINE]
Free Article
10.

Inactivation of DNA-dependent protein kinase leads to spindle disruption and mitotic catastrophe with attenuated checkpoint protein 2 Phosphorylation in response to DNA damage.

Shang ZF, Huang B, Xu QZ, Zhang SM, Fan R, Liu XD, Wang Y, Zhou PK.

Cancer Res. 2010 May 1;70(9):3657-66. doi: 10.1158/0008-5472.CAN-09-3362. Epub 2010 Apr 20.

PMID:
20406977
[PubMed - indexed for MEDLINE]
Free Article
12.
13.

DNA damage during the spindle-assembly checkpoint degrades CDC25A, inhibits cyclin-CDC2 complexes, and reverses cells to interphase.

Chow JP, Siu WY, Fung TK, Chan WM, Lau A, Arooz T, Ng CP, Yamashita K, Poon RY.

Mol Biol Cell. 2003 Oct;14(10):3989-4002. Epub 2003 Jul 25.

PMID:
14517313
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Chk2 is required for optimal mitotic delay in response to irradiation-induced DNA damage incurred in G2 phase.

Rainey MD, Black EJ, Zachos G, Gillespie DA.

Oncogene. 2008 Feb 7;27(7):896-906. Epub 2007 Aug 6.

PMID:
17684483
[PubMed - indexed for MEDLINE]
15.

DNA replication defects, spontaneous DNA damage, and ATM-dependent checkpoint activation in replication protein A-deficient cells.

Dodson GE, Shi Y, Tibbetts RS.

J Biol Chem. 2004 Aug 6;279(32):34010-4. Epub 2004 Jun 14.

PMID:
15197179
[PubMed - indexed for MEDLINE]
Free Article
16.

The Plk1 Polo box domain mediates a cell cycle and DNA damage regulated interaction with Chk2.

Tsvetkov LM, Tsekova RT, Xu X, Stern DF.

Cell Cycle. 2005 Apr;4(4):609-17. Epub 2005 Apr 9.

PMID:
15876876
[PubMed - indexed for MEDLINE]
Free Article
17.

Oncogenic RAS induces accelerated transition through G2/M and promotes defects in the G2 DNA damage and mitotic spindle checkpoints.

Knauf JA, Ouyang B, Knudsen ES, Fukasawa K, Babcock G, Fagin JA.

J Biol Chem. 2006 Feb 17;281(7):3800-9. Epub 2005 Nov 29.

PMID:
16316983
[PubMed - indexed for MEDLINE]
Free Article
18.

Dual regulation of Cdc25A by Chk1 and p53-ATF3 in DNA replication checkpoint control.

Demidova AR, Aau MY, Zhuang L, Yu Q.

J Biol Chem. 2009 Feb 13;284(7):4132-9. doi: 10.1074/jbc.M808118200. Epub 2008 Dec 7.

PMID:
19060337
[PubMed - indexed for MEDLINE]
Free Article
19.

Phosphorylation of serine 1387 in Brca1 is specifically required for the Atm-mediated S-phase checkpoint after ionizing irradiation.

Xu B, O'Donnell AH, Kim ST, Kastan MB.

Cancer Res. 2002 Aug 15;62(16):4588-91.

PMID:
12183412
[PubMed - indexed for MEDLINE]
Free Article
20.

Critical role for mouse Hus1 in an S-phase DNA damage cell cycle checkpoint.

Weiss RS, Leder P, Vaziri C.

Mol Cell Biol. 2003 Feb;23(3):791-803.

PMID:
12529385
[PubMed - indexed for MEDLINE]
Free PMC Article

Display Settings:

Format
Items per page
Sort by

Send to:

Choose Destination

Supplemental Content

Write to the Help Desk