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Results: 1 to 20 of 99

1.

c-Met must translocate to the nucleus to initiate calcium signals.

Gomes DA, Rodrigues MA, Leite MF, Gomez MV, Varnai P, Balla T, Bennett AM, Nathanson MH.

J Biol Chem. 2008 Feb 15;283(7):4344-51. Epub 2007 Dec 11.

PMID:
18073207
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Involvement of PI3K/Akt signaling pathway in hepatocyte growth factor-induced migration of uveal melanoma cells.

Ye M, Hu D, Tu L, Zhou X, Lu F, Wen B, Wu W, Lin Y, Zhou Z, Qu J.

Invest Ophthalmol Vis Sci. 2008 Feb;49(2):497-504. doi: 10.1167/iovs.07-0975.

PMID:
18234991
[PubMed - indexed for MEDLINE]
Free Article
3.

The multisubstrate adapter Gab1 regulates hepatocyte growth factor (scatter factor)-c-Met signaling for cell survival and DNA repair.

Fan S, Ma YX, Gao M, Yuan RQ, Meng Q, Goldberg ID, Rosen EM.

Mol Cell Biol. 2001 Aug;21(15):4968-84.

PMID:
11438654
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Hepatocyte growth factor-induced BMP-2 expression is mediated by c-Met receptor, FAK, JNK, Runx2, and p300 pathways in human osteoblasts.

Tsai SY, Huang YL, Yang WH, Tang CH.

Int Immunopharmacol. 2012 Jun;13(2):156-62. doi: 10.1016/j.intimp.2012.03.026. Epub 2012 Apr 11.

PMID:
22504529
[PubMed - indexed for MEDLINE]
5.

Hepatocyte growth factor induces Wnt-independent nuclear translocation of beta-catenin after Met-beta-catenin dissociation in hepatocytes.

Monga SP, Mars WM, Pediaditakis P, Bell A, Mulé K, Bowen WC, Wang X, Zarnegar R, Michalopoulos GK.

Cancer Res. 2002 Apr 1;62(7):2064-71.

PMID:
11929826
[PubMed - indexed for MEDLINE]
Free Article
6.

Overexpression of c-Met and CD44v6 receptors contributes to autocrine TGF-β1 signaling in interstitial lung disease.

Ghatak S, Bogatkevich GS, Atnelishvili I, Akter T, Feghali-Bostwick C, Hoffman S, Fresco VM, Fuchs JC, Visconti RP, Markwald RR, Padhye SB, Silver RM, Hascall VC, Misra S.

J Biol Chem. 2014 Mar 14;289(11):7856-72. doi: 10.1074/jbc.M113.505065. Epub 2013 Dec 9.

PMID:
24324260
[PubMed - indexed for MEDLINE]
7.

Role of c-Met/phosphatidylinositol 3-kinase (PI3k)/Akt signaling in hepatocyte growth factor (HGF)-mediated lamellipodia formation, reactive oxygen species (ROS) generation, and motility of lung endothelial cells.

Usatyuk PV, Fu P, Mohan V, Epshtein Y, Jacobson JR, Gomez-Cambronero J, Wary KK, Bindokas V, Dudek SM, Salgia R, Garcia JG, Natarajan V.

J Biol Chem. 2014 May 9;289(19):13476-91. doi: 10.1074/jbc.M113.527556. Epub 2014 Mar 14.

PMID:
24634221
[PubMed - indexed for MEDLINE]
8.

Adaptor molecule Crk is required for sustained phosphorylation of Grb2-associated binder 1 and hepatocyte growth factor-induced cell motility of human synovial sarcoma cell lines.

Watanabe T, Tsuda M, Makino Y, Ichihara S, Sawa H, Minami A, Mochizuki N, Nagashima K, Tanaka S.

Mol Cancer Res. 2006 Jul;4(7):499-510.

PMID:
16849525
[PubMed - indexed for MEDLINE]
Free Article
9.

A selective c-met inhibitor blocks an autocrine hepatocyte growth factor growth loop in ANBL-6 cells and prevents migration and adhesion of myeloma cells.

Hov H, Holt RU, Rø TB, Fagerli UM, Hjorth-Hansen H, Baykov V, Christensen JG, Waage A, Sundan A, Børset M.

Clin Cancer Res. 2004 Oct 1;10(19):6686-94.

PMID:
15475459
[PubMed - indexed for MEDLINE]
Free Article
10.

Hepatocyte growth factor activates several transduction pathways in rat pancreatic acini.

Aparicio IM, Garcia-Marin LJ, Andreolotti AG, Bodega G, Jensen RT, Bragado MJ.

Biochim Biophys Acta. 2003 Dec 7;1643(1-3):37-46.

PMID:
14654226
[PubMed - indexed for MEDLINE]
11.

Anti-apoptotic role of caspase-cleaved GAB1 adaptor protein in hepatocyte growth factor/scatter factor-MET receptor protein signaling.

Le Goff A, Ji Z, Leclercq B, Bourette RP, Mougel A, Guerardel C, de Launoit Y, Vicogne J, Goormachtigh G, Fafeur V.

J Biol Chem. 2012 Oct 12;287(42):35382-96. doi: 10.1074/jbc.M112.409797. Epub 2012 Aug 22.

PMID:
22915589
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

The Gab1 PH domain is required for localization of Gab1 at sites of cell-cell contact and epithelial morphogenesis downstream from the met receptor tyrosine kinase.

Maroun CR, Holgado-Madruga M, Royal I, Naujokas MA, Fournier TM, Wong AJ, Park M.

Mol Cell Biol. 1999 Mar;19(3):1784-99.

PMID:
10022866
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Oncogenic Met receptor induces cell-cycle progression in Xenopus oocytes independent of direct Grb2 and Shc binding or Mos synthesis, but requires phosphatidylinositol 3-kinase and Raf signaling.

Mood K, Saucier C, Ishimura A, Bong YS, Lee HS, Park M, Daar IO.

J Cell Physiol. 2006 Apr;207(1):271-85.

PMID:
16331688
[PubMed - indexed for MEDLINE]
14.

Signaling pathways involved in cyclooxygenase-2 induction by hepatocyte growth factor in non small-cell lung cancer.

Siegfried JM, Gubish CT, Rothstein ME, Queiroz de Oliveira PE, Stabile LP.

Mol Pharmacol. 2007 Sep;72(3):769-79. Epub 2007 Jun 5.

PMID:
17550984
[PubMed - indexed for MEDLINE]
Free Article
15.

Differential signaling by alternative HGF isoforms through c-Met: activation of both MAP kinase and PI 3-kinase pathways is insufficient for mitogenesis.

Day RM, Cioce V, Breckenridge D, Castagnino P, Bottaro DP.

Oncogene. 1999 Jun 3;18(22):3399-406.

PMID:
10362361
[PubMed - indexed for MEDLINE]
Free Article
16.

Constitutively active c-Met kinase in PC-3 cells is autocrine-independent and can be blocked by the Met kinase inhibitor BMS-777607.

Dai Y, Siemann DW.

BMC Cancer. 2012 May 28;12:198. doi: 10.1186/1471-2407-12-198.

PMID:
22639908
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Modulation of the c-Met/hepatocyte growth factor pathway in small cell lung cancer.

Maulik G, Kijima T, Ma PC, Ghosh SK, Lin J, Shapiro GI, Schaefer E, Tibaldi E, Johnson BE, Salgia R.

Clin Cancer Res. 2002 Feb;8(2):620-7.

PMID:
11839685
[PubMed - indexed for MEDLINE]
Free Article
18.

Degradation of the GAB1 adaptor by the ubiquitin-proteasome pathway hampers HGF/SF-MET signaling.

Goormachtigh G, Ji Z, Le Goff A, Fafeur V.

Biochem Biophys Res Commun. 2011 Aug 12;411(4):780-5. doi: 10.1016/j.bbrc.2011.07.024. Epub 2011 Jul 18.

PMID:
21782801
[PubMed - indexed for MEDLINE]
19.

Matriptase is required for the active form of hepatocyte growth factor induced Met, focal adhesion kinase and protein kinase B activation on neural stem/progenitor cell motility.

Fang JD, Lee SL.

Biochim Biophys Acta. 2014 Jul;1843(7):1285-94. doi: 10.1016/j.bbamcr.2014.03.020. Epub 2014 Mar 28.

PMID:
24685580
[PubMed - indexed for MEDLINE]
20.

Differential phosphorylation of the docking protein Gab1 by c-Src and the hepatocyte growth factor receptor regulates different aspects of cell functions.

Chan PC, Sudhakar JN, Lai CC, Chen HC.

Oncogene. 2010 Feb 4;29(5):698-710. doi: 10.1038/onc.2009.363. Epub 2009 Nov 2.

PMID:
19881549
[PubMed - indexed for MEDLINE]

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