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Items: 1 to 20 of 130

1.

Glial expression of cannabinoid CB(2) receptors and fatty acid amide hydrolase are beta amyloid-linked events in Down's syndrome.

Núñez E, Benito C, Tolón RM, Hillard CJ, Griffin WS, Romero J.

Neuroscience. 2008 Jan 2;151(1):104-10. Epub 2007 Nov 4.

PMID:
18068305
2.

Cannabinoid CB1 and CB2 receptors and fatty acid amide hydrolase are specific markers of plaque cell subtypes in human multiple sclerosis.

Benito C, Romero JP, Tolón RM, Clemente D, Docagne F, Hillard CJ, Guaza C, Romero J.

J Neurosci. 2007 Feb 28;27(9):2396-402.

3.

Cannabinoid CB2 receptors and fatty acid amide hydrolase are selectively overexpressed in neuritic plaque-associated glia in Alzheimer's disease brains.

Benito C, Núñez E, Tolón RM, Carrier EJ, Rábano A, Hillard CJ, Romero J.

J Neurosci. 2003 Dec 3;23(35):11136-41.

6.

β-Amyloid exacerbates inflammation in astrocytes lacking fatty acid amide hydrolase through a mechanism involving PPAR-α, PPAR-γ and TRPV1, but not CB₁ or CB₂ receptors.

Benito C, Tolón RM, Castillo AI, Ruiz-Valdepeñas L, Martínez-Orgado JA, Fernández-Sánchez FJ, Vázquez C, Cravatt BF, Romero J.

Br J Pharmacol. 2012 Jun;166(4):1474-89. doi: 10.1111/j.1476-5381.2012.01889.x.

7.

The activation of cannabinoid CB2 receptors stimulates in situ and in vitro beta-amyloid removal by human macrophages.

Tolón RM, Núñez E, Pazos MR, Benito C, Castillo AI, Martínez-Orgado JA, Romero J.

Brain Res. 2009 Aug 4;1283:148-54. doi: 10.1016/j.brainres.2009.05.098. Epub 2009 Jun 6.

PMID:
19505450
8.
9.

Amyloid A4 protein and its precursor in Down's syndrome and Alzheimer's disease.

Rumble B, Retallack R, Hilbich C, Simms G, Multhaup G, Martins R, Hockey A, Montgomery P, Beyreuther K, Masters CL.

N Engl J Med. 1989 Jun 1;320(22):1446-52.

PMID:
2566117
10.

Overexpression of s100beta in Down's syndrome: correlation with patient age and with beta-amyloid deposition.

Royston MC, McKenzie JE, Gentleman SM, Sheng JG, Mann DM, Griffin WS, Mrak RE.

Neuropathol Appl Neurobiol. 1999 Oct;25(5):387-93.

PMID:
10564528
11.

Presence of soluble amyloid beta-peptide precedes amyloid plaque formation in Down's syndrome.

Teller JK, Russo C, DeBusk LM, Angelini G, Zaccheo D, Dagna-Bricarelli F, Scartezzini P, Bertolini S, Mann DM, Tabaton M, Gambetti P.

Nat Med. 1996 Jan;2(1):93-5.

PMID:
8564851
12.

Localization of superoxide dismutases in Alzheimer's disease and Down's syndrome neocortex and hippocampus.

Furuta A, Price DL, Pardo CA, Troncoso JC, Xu ZS, Taniguchi N, Martin LJ.

Am J Pathol. 1995 Feb;146(2):357-67.

13.

A glial endogenous cannabinoid system is upregulated in the brains of macaques with simian immunodeficiency virus-induced encephalitis.

Benito C, Kim WK, Chavarría I, Hillard CJ, Mackie K, Tolón RM, Williams K, Romero J.

J Neurosci. 2005 Mar 9;25(10):2530-6. Erratum in: J Neurosci. 2005 Mar 30;25(13):1 p following 3477. Kim, Wong-Ki [corrected to Kim, Woong-Ki];Williams, Ken [corrected to Williams, Kenneth].

14.

Evidence of amyloid beta-protein immunoreactive early plaque lesions in Down's syndrome brains.

Ikeda S, Yanagisawa N, Allsop D, Glenner GG.

Lab Invest. 1989 Jul;61(1):133-7.

PMID:
2473275
15.

Effect of cannabidiol on sepsis-induced motility disturbances in mice: involvement of CB receptors and fatty acid amide hydrolase.

de Filippis D, Iuvone T, d'amico A, Esposito G, Steardo L, Herman AG, Pelckmans PA, de Winter BY, de Man JG.

Neurogastroenterol Motil. 2008 Aug;20(8):919-27. doi: 10.1111/j.1365-2982.2008.01114.x. Epub 2008 Mar 27.

16.

beta-Amyloid regulates gene expression of glial trophic substance S100 beta in C6 glioma and primary astrocyte cultures.

Peña LA, Brecher CW, Marshak DR.

Brain Res Mol Brain Res. 1995 Dec 1;34(1):118-26.

PMID:
8750867
17.

Up-regulation of E2F-1 in Down's syndrome brain exhibiting neuropathological features of Alzheimer-type dementia.

Motonaga K, Itoh M, Hirayama A, Hirano S, Becker LE, Goto Y, Takashima S.

Brain Res. 2001 Jun 29;905(1-2):250-3.

PMID:
11423103
18.

Alzheimer's disease and Down's syndrome: sharing of a unique cerebrovascular amyloid fibril protein.

Glenner GG, Wong CW.

Biochem Biophys Res Commun. 1984 Aug 16;122(3):1131-5.

PMID:
6236805
19.

Early senile plaques in Down's syndrome brains show a close relationship with cell bodies of neurons.

Allsop D, Haga SI, Haga C, Ikeda SI, Mann DM, Ishii T.

Neuropathol Appl Neurobiol. 1989 Nov-Dec;15(6):531-42.

PMID:
2559339
20.

Opposing control of cannabinoid receptor stimulation on amyloid-beta-induced reactive gliosis: in vitro and in vivo evidence.

Esposito G, Iuvone T, Savani C, Scuderi C, De Filippis D, Papa M, Di Marzo V, Steardo L.

J Pharmacol Exp Ther. 2007 Sep;322(3):1144-52. Epub 2007 Jun 1.

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