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Results: 1 to 20 of 96

1.

Insulin-like signaling, nutrient homeostasis, and life span.

Taguchi A, White MF.

Annu Rev Physiol. 2008;70:191-212. Review.

PMID:
17988211
[PubMed - indexed for MEDLINE]
2.

Brain IRS2 signaling coordinates life span and nutrient homeostasis.

Taguchi A, Wartschow LM, White MF.

Science. 2007 Jul 20;317(5836):369-72.

PMID:
17641201
[PubMed - indexed for MEDLINE]
Free Article
3.

Repression of a potassium channel by nuclear hormone receptor and TGF-β signaling modulates insulin signaling in Caenorhabditis elegans.

Park D, Jones KL, Lee H, Snutch TP, Taubert S, Riddle DL.

PLoS Genet. 2012;8(2):e1002519. doi: 10.1371/journal.pgen.1002519. Epub 2012 Feb 16.

PMID:
22359515
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

C. elegans VANG-1 modulates life span via insulin/IGF-1-like signaling.

Honnen SJ, Büchter C, Schröder V, Hoffmann M, Kohara Y, Kampkötter A, Bossinger O.

PLoS One. 2012;7(2):e32183. doi: 10.1371/journal.pone.0032183. Epub 2012 Feb 16.

PMID:
22359667
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

An insulin-like signaling pathway affects both longevity and reproduction in Caenorhabditis elegans.

Tissenbaum HA, Ruvkun G.

Genetics. 1998 Feb;148(2):703-17.

PMID:
9504918
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Gene activities that mediate increased life span of C. elegans insulin-like signaling mutants.

Samuelson AV, Carr CE, Ruvkun G.

Genes Dev. 2007 Nov 15;21(22):2976-94.

PMID:
18006689
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Running on empty: how p53 controls INS/IGF signaling and affects life span.

Scrable H, Medrano S, Ungewitter E.

Exp Gerontol. 2009 Jan-Feb;44(1-2):93-100. doi: 10.1016/j.exger.2008.05.017. Epub 2008 Jun 13. Review.

PMID:
18598747
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Central and peripheral effects of insulin/IGF-1 signaling in aging and cancer: antidiabetic drugs as geroprotectors and anticarcinogens.

Anisimov VN, Berstein LM, Popovich IG, Zabezhinski MA, Egormin PA, Tyndyk ML, Anikin IV, Semenchenko AV, Yashin AI.

Ann N Y Acad Sci. 2005 Dec;1057:220-34.

PMID:
16399897
[PubMed - indexed for MEDLINE]
9.

Extension of life-span by loss of CHICO, a Drosophila insulin receptor substrate protein.

Clancy DJ, Gems D, Harshman LG, Oldham S, Stocker H, Hafen E, Leevers SJ, Partridge L.

Science. 2001 Apr 6;292(5514):104-6.

PMID:
11292874
[PubMed - indexed for MEDLINE]
Free Article
10.

Dominant-negative Dmp53 extends life span through the dTOR pathway in D. melanogaster.

Bauer JH, Chang C, Bae G, Morris SN, Helfand SL.

Mech Ageing Dev. 2010 Mar;131(3):193-201. doi: 10.1016/j.mad.2010.01.007. Epub 2010 Feb 1.

PMID:
20117129
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Impaired insulin/IGF1 signaling extends life span by promoting mitochondrial L-proline catabolism to induce a transient ROS signal.

Zarse K, Schmeisser S, Groth M, Priebe S, Beuster G, Kuhlow D, Guthke R, Platzer M, Kahn CR, Ristow M.

Cell Metab. 2012 Apr 4;15(4):451-65. doi: 10.1016/j.cmet.2012.02.013.

PMID:
22482728
[PubMed - indexed for MEDLINE]
Free Article
12.

daf-2, an insulin receptor-like gene that regulates longevity and diapause in Caenorhabditis elegans.

Kimura KD, Tissenbaum HA, Liu Y, Ruvkun G.

Science. 1997 Aug 15;277(5328):942-6.

PMID:
9252323
[PubMed - indexed for MEDLINE]
Free Article
13.

Polyunsaturated fatty acids are involved in regulatory mechanism of fatty acid homeostasis via daf-2/insulin signaling in Caenorhabditis elegans.

Horikawa M, Sakamoto K.

Mol Cell Endocrinol. 2010 Jul 29;323(2):183-92. doi: 10.1016/j.mce.2010.03.004. Epub 2010 Mar 11.

PMID:
20226839
[PubMed - indexed for MEDLINE]
14.

LET-60 RAS modulates effects of insulin/IGF-1 signaling on development and aging in Caenorhabditis elegans.

Nanji M, Hopper NA, Gems D.

Aging Cell. 2005 Oct;4(5):235-45.

PMID:
16164423
[PubMed - indexed for MEDLINE]
15.

CNS insulin signaling in the control of energy homeostasis and glucose metabolism - from embryo to old age.

Vogt MC, Brüning JC.

Trends Endocrinol Metab. 2013 Feb;24(2):76-84. doi: 10.1016/j.tem.2012.11.004. Epub 2012 Dec 19. Review.

PMID:
23265947
[PubMed - indexed for MEDLINE]
16.

PTP1B and TCPTP--nonredundant phosphatases in insulin signaling and glucose homeostasis.

Tiganis T.

FEBS J. 2013 Jan;280(2):445-58. doi: 10.1111/j.1742-4658.2012.08563.x. Epub 2012 Apr 18. Review.

PMID:
22404968
[PubMed - indexed for MEDLINE]
17.

[Impaired insulin signaling and human ageing].

Ksiazek K, Witowski J.

Postepy Hig Med Dosw (Online). 2008 May 29;62:263-71. Review. Polish.

PMID:
18542047
[PubMed - indexed for MEDLINE]
Free Article
18.

Aging: all in the head?

Bartke A.

Cell Metab. 2007 Sep;6(3):153-4.

PMID:
17767900
[PubMed - indexed for MEDLINE]
Free Article
19.

SHC-1/p52Shc targets the insulin/IGF-1 and JNK signaling pathways to modulate life span and stress response in C. elegans.

Neumann-Haefelin E, Qi W, Finkbeiner E, Walz G, Baumeister R, Hertweck M.

Genes Dev. 2008 Oct 1;22(19):2721-35. doi: 10.1101/gad.478408.

PMID:
18832074
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Oxidative stress and life span determination in the nematode Caenorhabditis elegans.

Honda Y, Honda S.

Ann N Y Acad Sci. 2002 Apr;959:466-74. Review.

PMID:
11976220
[PubMed - indexed for MEDLINE]

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