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Catalytically inactive anthrax toxin(s) are potential prophylactic agents.

Gupta M, Alam S, Bhatnagar R.

Vaccine. 2007 Dec 5;25(50):8410-9. Epub 2007 Oct 16.


Protective immunity induced by Bacillus anthracis toxin-deficient strains.

Pezard C, Weber M, Sirard JC, Berche P, Mock M.

Infect Immun. 1995 Apr;63(4):1369-72.


Investigation of new dominant-negative inhibitors of anthrax protective antigen mutants for use in therapy and vaccination.

Cao S, Guo A, Liu Z, Tan Y, Wu G, Zhang C, Zhao Y, Chen H.

Infect Immun. 2009 Oct;77(10):4679-87. doi: 10.1128/IAI.00264-09. Epub 2009 Jul 20.


A cationic lipid-formulated plasmid DNA vaccine confers sustained antibody-mediated protection against aerosolized anthrax spores.

Hermanson G, Whitlow V, Parker S, Tonsky K, Rusalov D, Ferrari M, Lalor P, Komai M, Mere R, Bell M, Brenneman K, Mateczun A, Evans T, Kaslow D, Galloway D, Hobart P.

Proc Natl Acad Sci U S A. 2004 Sep 14;101(37):13601-6. Epub 2004 Sep 1.


Anthrax protective antigen delivered by Salmonella enterica serovar Typhi Ty21a protects mice from a lethal anthrax spore challenge.

Osorio M, Wu Y, Singh S, Merkel TJ, Bhattacharyya S, Blake MS, Kopecko DJ.

Infect Immun. 2009 Apr;77(4):1475-82. doi: 10.1128/IAI.00828-08. Epub 2009 Jan 29.


Protective activity and immunogenicity of two recombinant anthrax vaccines for veterinary use.

Fasanella A, Tonello F, Garofolo G, Muraro L, Carattoli A, Adone R, Montecucco C.

Vaccine. 2008 Oct 23;26(45):5684-8. doi: 10.1016/j.vaccine.2008.08.026. Epub 2008 Sep 4.


Protection against anthrax lethal toxin challenge by genetic immunization with a plasmid encoding the lethal factor protein.

Price BM, Liner AL, Park S, Leppla SH, Mateczun A, Galloway DR.

Infect Immun. 2001 Jul;69(7):4509-15.


Role of anthrax toxins in dissemination, disease progression, and induction of protective adaptive immunity in the mouse aerosol challenge model.

Loving CL, Khurana T, Osorio M, Lee GM, Kelly VK, Stibitz S, Merkel TJ.

Infect Immun. 2009 Jan;77(1):255-65. doi: 10.1128/IAI.00633-08. Epub 2008 Oct 27.


Nasal immunization with the mixture of PA63, LF, and a PGA conjugate induced strong antibody responses against all three antigens.

Sloat BR, Shaker DS, Le UM, Cui Z.

FEMS Immunol Med Microbiol. 2008 Mar;52(2):169-79. doi: 10.1111/j.1574-695X.2007.00347.x. Epub 2008 Jan 9.


Anthrax toxin.

Bhatnagar R, Batra S.

Crit Rev Microbiol. 2001;27(3):167-200. Review.


Characterization of the human immune response to the UK anthrax vaccine.

Baillie L, Townend T, Walker N, Eriksson U, Williamson D.

FEMS Immunol Med Microbiol. 2004 Oct 1;42(2):267-70.


Poly-gamma-d-glutamic acid and protective antigen conjugate vaccines induce functional antibodies against the protective antigen and capsule of Bacillus anthracis in guinea-pigs and rabbits.

Lee DY, Chun JH, Ha HJ, Park J, Kim BS, Oh HB, Rhie GE.

FEMS Immunol Med Microbiol. 2009 Nov;57(2):165-72. doi: 10.1111/j.1574-695X.2009.00595.x. Epub 2009 Aug 6.


Enhancement of antibody responses to Bacillus anthracis protective antigen domain IV by use of calreticulin as a chimeric molecular adjuvant.

Park YS, Lee JH, Hung CF, Wu TC, Kim TW.

Infect Immun. 2008 May;76(5):1952-9. doi: 10.1128/IAI.01722-07. Epub 2008 Feb 19.


Efficacy of non-toxic deletion mutants of protective antigen from Bacillus anthracis.

Rhie GE, Park YM, Han JS, Yu JY, Seong WK, Oh HB.

FEMS Immunol Med Microbiol. 2005 Aug 1;45(2):341-7.


LRP5 and LRP6 are not required for protective antigen-mediated internalization or lethality of anthrax lethal toxin.

Young JJ, Bromberg-White JL, Zylstra C, Church JT, Boguslawski E, Resau JH, Williams BO, Duesbery NS.

PLoS Pathog. 2007 Mar;3(3):e27.


Role of toxin functional domains in anthrax pathogenesis.

Brossier F, Weber-Levy M, Mock M, Sirard JC.

Infect Immun. 2000 Apr;68(4):1781-6.


Contribution of individual toxin components to virulence of Bacillus anthracis.

Pezard C, Berche P, Mock M.

Infect Immun. 1991 Oct;59(10):3472-7.


Plasmid-based vaccination with candidate anthrax vaccine antigens induces durable type 1 and type 2 T-helper immune responses.

Zhang Y, Qiu J, Zhou Y, Farhangfar F, Hester J, Lin AY, Decker WK.

Vaccine. 2008 Jan 30;26(5):614-22. doi: 10.1016/j.vaccine.2007.11.072. Epub 2007 Dec 18.

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