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Results: 1 to 20 of 559

1.

The role of the intestine in drug metabolism and pharmacokinetics: an industry perspective.

Fisher MB, Labissiere G.

Curr Drug Metab. 2007 Oct;8(7):694-9. Review.

PMID:
17979657
[PubMed - indexed for MEDLINE]
2.

In vitro methods to study intestinal drug metabolism.

van de Kerkhof EG, de Graaf IA, Groothuis GM.

Curr Drug Metab. 2007 Oct;8(7):658-75. Review.

PMID:
17979654
[PubMed - indexed for MEDLINE]
3.

Intestinal first-pass metabolism: bridging the gap between in vitro and in vivo.

Galetin A.

Curr Drug Metab. 2007 Oct;8(7):643-4. No abstract available.

PMID:
17979662
[PubMed - indexed for MEDLINE]
4.

High-throughput screening approaches for investigating drug metabolism and pharmacokinetics.

Roberts SA.

Xenobiotica. 2001 Aug-Sep;31(8-9):557-89. Review.

PMID:
11569526
[PubMed - indexed for MEDLINE]
5.

Metabolism and toxicity of drugs. Two decades of progress in industrial drug metabolism.

Baillie TA.

Chem Res Toxicol. 2008 Jan;21(1):129-37. Epub 2007 Dec 4. Review.

PMID:
18052111
[PubMed - indexed for MEDLINE]
6.

A comparison of pharmacokinetics between humans and monkeys.

Akabane T, Tabata K, Kadono K, Sakuda S, Terashita S, Teramura T.

Drug Metab Dispos. 2010 Feb;38(2):308-16. doi: 10.1124/dmd.109.028829. Epub 2009 Nov 12.

PMID:
19910513
[PubMed - indexed for MEDLINE]
Free Article
7.

Drug metabolism in chronic renal failure.

Pichette V, Leblond FA.

Curr Drug Metab. 2003 Apr;4(2):91-103. Review.

PMID:
12678690
[PubMed - indexed for MEDLINE]
8.

Prediction of intestinal first-pass drug metabolism.

Yang J, Jamei M, Yeo KR, Tucker GT, Rostami-Hodjegan A.

Curr Drug Metab. 2007 Oct;8(7):676-84. Review.

PMID:
17979655
[PubMed - indexed for MEDLINE]
9.

Animal models and intestinal drug transport.

Glaeser H, Fromm MF.

Expert Opin Drug Metab Toxicol. 2008 Apr;4(4):347-61. doi: 10.1517/17425255.4.4.347 . Review.

PMID:
18433341
[PubMed - indexed for MEDLINE]
10.

Intestinal and hepatic glucuronidation of flavonoids.

Zhang L, Zuo Z, Lin G.

Mol Pharm. 2007 Nov-Dec;4(6):833-45. Epub 2007 Nov 3. Review.

PMID:
17979245
[PubMed - indexed for MEDLINE]
11.

Potential role of intestinal first-pass metabolism in the prediction of drug-drug interactions.

Galetin A, Gertz M, Houston JB.

Expert Opin Drug Metab Toxicol. 2008 Jul;4(7):909-22. doi: 10.1517/17425255.4.7.909 . Review.

PMID:
18624679
[PubMed - indexed for MEDLINE]
12.

Prediction of human pharmacokinetics--gut-wall metabolism.

Fagerholm U.

J Pharm Pharmacol. 2007 Oct;59(10):1335-43. Review.

PMID:
17910807
[PubMed - indexed for MEDLINE]
13.
14.

Intestinal UGTs as potential modifiers of pharmacokinetics and biological responses to drugs and xenobiotics.

Ritter JK.

Expert Opin Drug Metab Toxicol. 2007 Feb;3(1):93-107. Review.

PMID:
17269897
[PubMed - indexed for MEDLINE]
15.

Maximal inhibition of intestinal first-pass metabolism as a pragmatic indicator of intestinal contribution to the drug-drug interactions for CYP3A4 cleared drugs.

Galetin A, Hinton LK, Burt H, Obach RS, Houston JB.

Curr Drug Metab. 2007 Oct;8(7):685-93. Review.

PMID:
17979656
[PubMed - indexed for MEDLINE]
16.

Predicting drug-drug interactions from in vitro drug metabolism data: challenges and recent advances.

Obach RS.

Curr Opin Drug Discov Devel. 2009 Jan;12(1):81-9.

PMID:
19152216
[PubMed - indexed for MEDLINE]
17.
18.

Effects of first-pass metabolism on metabolite mean residence time determination after oral administration of parent drug.

Chan KK, Gibaldi M.

Pharm Res. 1990 Jan;7(1):59-63.

PMID:
2300537
[PubMed - indexed for MEDLINE]
19.

Frog intestinal sac as an in vitro method for the assessment of intestinal permeability in humans: Application to carrier transported drugs.

Franco M, Lopedota A, Trapani A, Cutrignelli A, Meleleo D, Micelli S, Trapani G.

Int J Pharm. 2008 Mar 20;352(1-2):182-8. Epub 2007 Dec 11.

PMID:
18055143
[PubMed - indexed for MEDLINE]
20.

An update on in vitro test methods in human hepatic drug biotransformation research: pros and cons.

Brandon EF, Raap CD, Meijerman I, Beijnen JH, Schellens JH.

Toxicol Appl Pharmacol. 2003 Jun 15;189(3):233-46. Review.

PMID:
12791308
[PubMed - indexed for MEDLINE]

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