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STAGA recruits Mediator to the MYC oncoprotein to stimulate transcription and cell proliferation.

Liu X, Vorontchikhina M, Wang YL, Faiola F, Martinez E.

Mol Cell Biol. 2008 Jan;28(1):108-21. Epub 2007 Oct 29.


MYC interacts with the human STAGA coactivator complex via multivalent contacts with the GCN5 and TRRAP subunits.

Zhang N, Ichikawa W, Faiola F, Lo SY, Liu X, Martinez E.

Biochim Biophys Acta. 2014 May;1839(5):395-405. doi: 10.1016/j.bbagrm.2014.03.017. Epub 2014 Apr 3.


Ataxin-7 is a subunit of GCN5 histone acetyltransferase-containing complexes.

Helmlinger D, Hardy S, Sasorith S, Klein F, Robert F, Weber C, Miguet L, Potier N, Van-Dorsselaer A, Wurtz JM, Mandel JL, Tora L, Devys D.

Hum Mol Genet. 2004 Jun 15;13(12):1257-65. Epub 2004 Apr 28.


A human SPT3-TAFII31-GCN5-L acetylase complex distinct from transcription factor IID.

Martinez E, Kundu TK, Fu J, Roeder RG.

J Biol Chem. 1998 Sep 11;273(37):23781-5. Erratum in: J Biol Chem 1998 Oct 16;273(42):27755.


c-Myc transformation domain recruits the human STAGA complex and requires TRRAP and GCN5 acetylase activity for transcription activation.

Liu X, Tesfai J, Evrard YA, Dent SY, Martinez E.

J Biol Chem. 2003 May 30;278(22):20405-12. Epub 2003 Mar 26.


TATA-binding protein-free TAF-containing complex (TFTC) and p300 are both required for efficient transcriptional activation.

Hardy S, Brand M, Mittler G, Yanagisawa J, Kato S, Meisterernst M, Tora L.

J Biol Chem. 2002 Sep 6;277(36):32875-82. Epub 2002 Jul 9.


Multivalent binding of p53 to the STAGA complex mediates coactivator recruitment after UV damage.

Gamper AM, Roeder RG.

Mol Cell Biol. 2008 Apr;28(8):2517-27. doi: 10.1128/MCB.01461-07. Epub 2008 Feb 4.


E2F transcriptional activation requires TRRAP and GCN5 cofactors.

Lang SE, McMahon SB, Cole MD, Hearing P.

J Biol Chem. 2001 Aug 31;276(35):32627-34. Epub 2001 Jun 19.


Simultaneous recruitment of coactivators by Gcn4p stimulates multiple steps of transcription in vivo.

Govind CK, Yoon S, Qiu H, Govind S, Hinnebusch AG.

Mol Cell Biol. 2005 Jul;25(13):5626-38.


An extensive requirement for transcription factor IID-specific TAF-1 in Caenorhabditis elegans embryonic transcription.

Walker AK, Shi Y, Blackwell TK.

J Biol Chem. 2004 Apr 9;279(15):15339-47. Epub 2004 Jan 15.


TAF9b (formerly TAF9L) is a bona fide TAF that has unique and overlapping roles with TAF9.

Frontini M, Soutoglou E, Argentini M, Bole-Feysot C, Jost B, Scheer E, Tora L.

Mol Cell Biol. 2005 Jun;25(11):4638-49.


IFN-Stimulated transcription through a TBP-free acetyltransferase complex escapes viral shutoff.

Paulson M, Press C, Smith E, Tanese N, Levy DE.

Nat Cell Biol. 2002 Feb;4(2):140-7.


Dual regulation of c-Myc by p300 via acetylation-dependent control of Myc protein turnover and coactivation of Myc-induced transcription.

Faiola F, Liu X, Lo S, Pan S, Zhang K, Lymar E, Farina A, Martinez E.

Mol Cell Biol. 2005 Dec;25(23):10220-34.


The STAGA subunit ADA2b is an important regulator of human GCN5 catalysis.

Gamper AM, Kim J, Roeder RG.

Mol Cell Biol. 2009 Jan;29(1):266-80. doi: 10.1128/MCB.00315-08. Epub 2008 Oct 20.


Both normal and polyglutamine- expanded ataxin-7 are components of TFTC-type GCN5 histone acetyltransferase- containing complexes.

Helmlinger D, Hardy S, Eberlin A, Devys D, Tora L.

Biochem Soc Symp. 2006;(73):155-63.


Human ATAC Is a GCN5/PCAF-containing acetylase complex with a novel NC2-like histone fold module that interacts with the TATA-binding protein.

Wang YL, Faiola F, Xu M, Pan S, Martinez E.

J Biol Chem. 2008 Dec 5;283(49):33808-15. doi: 10.1074/jbc.M806936200. Epub 2008 Oct 6.


Human STAGA complex is a chromatin-acetylating transcription coactivator that interacts with pre-mRNA splicing and DNA damage-binding factors in vivo.

Martinez E, Palhan VB, Tjernberg A, Lymar ES, Gamper AM, Kundu TK, Chait BT, Roeder RG.

Mol Cell Biol. 2001 Oct;21(20):6782-95.


A TFTC/STAGA module mediates histone H2A and H2B deubiquitination, coactivates nuclear receptors, and counteracts heterochromatin silencing.

Zhao Y, Lang G, Ito S, Bonnet J, Metzger E, Sawatsubashi S, Suzuki E, Le Guezennec X, Stunnenberg HG, Krasnov A, Georgieva SG, Schüle R, Takeyama K, Kato S, Tora L, Devys D.

Mol Cell. 2008 Jan 18;29(1):92-101. doi: 10.1016/j.molcel.2007.12.011.

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