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Results: 1 to 20 of 120

1.

Electrocardiographic method for identifying drug-induced repolarization abnormalities associated with a reduction of the rapidly activating delayed rectifier potassium current.

Couderc JP, Vaglio M, Xia X, McNitt S, Hyrien O.

Conf Proc IEEE Eng Med Biol Soc. 2006;1:4010-5.

PMID:
17946595
[PubMed - indexed for MEDLINE]
2.

Improving the detection of subtle I(Kr)-inhibition: assessing electrocardiographic abnormalities of repolarization induced by moxifloxacin.

Couderc JP, McNitt S, Hyrien O, Vaglio M, Xia X, Polonsky S, Moss AJ, Zareba W.

Drug Saf. 2008;31(3):249-60.

PMID:
18302449
[PubMed - indexed for MEDLINE]
3.

Identifying drug-induced repolarization abnormalities from distinct ECG patterns in congenital long QT syndrome: a study of sotalol effects on T-wave morphology.

Graff C, Andersen MP, Xue JQ, Hardahl TB, Kanters JK, Toft E, Christiansen M, Jensen HK, Struijk JJ.

Drug Saf. 2009;32(7):599-611. doi: 10.2165/00002018-200932070-00006.

PMID:
19530746
[PubMed - indexed for MEDLINE]
4.

The use of beat-to-beat electrocardiogram analysis to distinguish QT/QTc interval changes caused by moxifloxacin from those caused by vardenafil.

Fossa AA, Langdon G, Couderc JP, Zhou M, Darpo B, Wilson F, Wallis R, Davis JD.

Clin Pharmacol Ther. 2011 Sep;90(3):449-54. doi: 10.1038/clpt.2011.139. Epub 2011 Aug 3.

PMID:
21814193
[PubMed - indexed for MEDLINE]
5.

A statistical assessment of QT data following placebo and moxifloxacin dosing in thorough QT studies.

Stylianou A, Roger J, Stephens K.

J Biopharm Stat. 2008;18(3):502-16. doi: 10.1080/10543400801995460.

PMID:
18470759
[PubMed - indexed for MEDLINE]
6.

Moxifloxacin-induced torsades de pointes.

Sherazi S, DiSalle M, Daubert JP, Shah AH.

Cardiol J. 2008;15(1):71-3.

PMID:
18651388
[PubMed - indexed for MEDLINE]
Free Article
7.

[Practical ECG problems in the elderly patient. Case number 16. Moxifloxacin-associated QT interval prolongation].

Farhoumand AD, Trombert V, Eusebio J.

Rev Med Suisse. 2011 Mar 16;7(286):624-5. French. No abstract available.

PMID:
21510347
[PubMed - indexed for MEDLINE]
8.

Moxifloxacin-induced QT prolongation and torsades: an uncommon effect of a common drug.

Badshah A, Janjua M, Younas F, Halabi AR, Cotant JF.

Am J Med Sci. 2009 Aug;338(2):164-6. doi: 10.1097/MAJ.0b013e3181a3c2c9.

PMID:
19680025
[PubMed - indexed for MEDLINE]
9.

T-wave morphology abnormalities in benign, potent, and arrhythmogenic I(kr) inhibition.

Couderc JP, Xia X, Peterson DR, McNitt S, Zhao H, Polonsky S, Moss AJ, Zareba W.

Heart Rhythm. 2011 Jul;8(7):1036-43. doi: 10.1016/j.hrthm.2011.02.005. Epub 2011 Feb 9.

PMID:
21315844
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Man versus machine: is there an optimal method for QT measurements in thorough QT studies?

Darpo B, Agin M, Kazierad DJ, Layton G, Muirhead G, Gray P, Jorkasky DK.

J Clin Pharmacol. 2006 Jun;46(6):598-612.

PMID:
16707406
[PubMed - indexed for MEDLINE]
11.

Antiarrhythmic properties of a rapid delayed-rectifier current activator in rabbit models of acquired long QT syndrome.

Diness TG, Yeh YH, Qi XY, Chartier D, Tsuji Y, Hansen RS, Olesen SP, Grunnet M, Nattel S.

Cardiovasc Res. 2008 Jul 1;79(1):61-9. doi: 10.1093/cvr/cvn075. Epub 2008 Mar 26.

PMID:
18367457
[PubMed - indexed for MEDLINE]
Free Article
12.

QT prolongation modifies dynamic restitution and hysteresis of the beat-to-beat QT-TQ interval relationship during normal sinus rhythm under varying states of repolarization.

Fossa AA, Wisialowski T, Crimin K.

J Pharmacol Exp Ther. 2006 Feb;316(2):498-506. Epub 2005 Oct 4.

PMID:
16204470
[PubMed - indexed for MEDLINE]
Free Article
13.

Response to letter to the editor: Statistical issues of QT prolongation assessment based on linear concentration modeling by Yi Tsong et al.

Wang Y, Garnett C.

J Biopharm Stat. 2010 May;20(3):689-92; author reply 693-7. doi: 10.1080/10543400903094881. No abstract available.

PMID:
20358447
[PubMed - indexed for MEDLINE]
14.

The effect of moxifloxacin on QTc and implications for the design of thorough QT studies.

Bloomfield DM, Kost JT, Ghosh K, Hreniuk D, Hickey LA, Guitierrez MJ, Gottesdiener K, Wagner JA.

Clin Pharmacol Ther. 2008 Oct;84(4):475-80.

PMID:
19238652
[PubMed - indexed for MEDLINE]
15.

Vardenafil-associated QTc changes: not merely a normal autonomic process.

Barbey JT.

Clin Pharmacol Ther. 2012 Apr;91(4):580; author reply 580-1. doi: 10.1038/clpt.2011.294. Epub 2012 Feb 29. No abstract available.

PMID:
22378160
[PubMed - indexed for MEDLINE]
16.

Effect of levetiracetam on cardiac repolarization in healthy subjects: a single-dose, randomized, placebo- and active-controlled, four-way crossover study.

Hulhoven R, Rosillon D, Bridson WE, Meeus MA, Salas E, Stockis A.

Clin Ther. 2008 Feb;30(2):260-70. doi: 10.1016/j.clinthera.2008.02.002.

PMID:
18343264
[PubMed - indexed for MEDLINE]
17.

Dexrazoxane protects the heart from acute doxorubicin-induced QT prolongation: a key role for I(Ks).

Ducroq J, Moha ou Maati H, Guilbot S, Dilly S, Laemmel E, Pons-Himbert C, Faivre JF, Bois P, Stücker O, Le Grand M.

Br J Pharmacol. 2010 Jan;159(1):93-101. doi: 10.1111/j.1476-5381.2009.00371.x. Epub 2009 Aug 24.

PMID:
19703166
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Revisit the combination validation test of Tsong et al. for thorough QT/QTc clinical trials.

Sun GG, Quan H.

J Biopharm Stat. 2010 May;20(3):683-7; author reply 688. doi: 10.1080/10543400903254790. No abstract available.

PMID:
20358445
[PubMed - indexed for MEDLINE]
19.

Drug-induced QT interval prolongation after ciprofloxacin administration in a patient receiving olanzapine.

Letsas KP, Sideris A, Kounas SP, Efremidis M, Korantzopoulos P, Kardaras F.

Int J Cardiol. 2006 May 10;109(2):273-4. Epub 2005 Jun 1.

PMID:
15935493
[PubMed - indexed for MEDLINE]
20.

Arrhythmias associated with fluoroquinolone therapy.

Falagas ME, Rafailidis PI, Rosmarakis ES.

Int J Antimicrob Agents. 2007 Apr;29(4):374-9. Epub 2007 Jan 22. Review.

PMID:
17241772
[PubMed - indexed for MEDLINE]

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