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Items: 1 to 20 of 196

1.

E1-L2 activates both ubiquitin and FAT10.

Chiu YH, Sun Q, Chen ZJ.

Mol Cell. 2007 Sep 21;27(6):1014-23.

2.

Mechanistic studies on activation of ubiquitin and di-ubiquitin-like protein, FAT10, by ubiquitin-like modifier activating enzyme 6, Uba6.

Gavin JM, Chen JJ, Liao H, Rollins N, Yang X, Xu Q, Ma J, Loke HK, Lingaraj T, Brownell JE, Mallender WD, Gould AE, Amidon BS, Dick LR.

J Biol Chem. 2012 May 4;287(19):15512-22. doi: 10.1074/jbc.M111.336198. Epub 2012 Mar 15.

3.

A novel protein-conjugating system for Ufm1, a ubiquitin-fold modifier.

Komatsu M, Chiba T, Tatsumi K, Iemura S, Tanida I, Okazaki N, Ueno T, Kominami E, Natsume T, Tanaka K.

EMBO J. 2004 May 5;23(9):1977-86. Epub 2004 Apr 8.

4.

Protein ubiquitination involving an E1-E2-E3 enzyme ubiquitin thioester cascade.

Scheffner M, Nuber U, Huibregtse JM.

Nature. 1995 Jan 5;373(6509):81-3.

PMID:
7800044
5.

Conjugation of the ubiquitin activating enzyme UBE1 with the ubiquitin-like modifier FAT10 targets it for proteasomal degradation.

Bialas J, Groettrup M, Aichem A.

PLoS One. 2015 Mar 13;10(3):e0120329. doi: 10.1371/journal.pone.0120329. eCollection 2015.

6.

FAT10, a ubiquitin-independent signal for proteasomal degradation.

Hipp MS, Kalveram B, Raasi S, Groettrup M, Schmidtke G.

Mol Cell Biol. 2005 May;25(9):3483-91.

7.

The ubiquitin-like protein FAT10 forms covalent conjugates and induces apoptosis.

Raasi S, Schmidtke G, Groettrup M.

J Biol Chem. 2001 Sep 21;276(38):35334-43. Epub 2001 Jul 9.

8.

Basis for a ubiquitin-like protein thioester switch toggling E1-E2 affinity.

Huang DT, Hunt HW, Zhuang M, Ohi MD, Holton JM, Schulman BA.

Nature. 2007 Jan 25;445(7126):394-8. Epub 2007 Jan 14.

9.

Structure of UBE2Z Enzyme Provides Functional Insight into Specificity in the FAT10 Protein Conjugation Machinery.

Schelpe J, Monté D, Dewitte F, Sixma TK, Rucktooa P.

J Biol Chem. 2016 Jan 8;291(2):630-9. doi: 10.1074/jbc.M115.671545. Epub 2015 Nov 10.

10.

Structural basis for recruitment of Ubc12 by an E2 binding domain in NEDD8's E1.

Huang DT, Paydar A, Zhuang M, Waddell MB, Holton JM, Schulman BA.

Mol Cell. 2005 Feb 4;17(3):341-50.

12.

Insights into the ubiquitin transfer cascade from the structure of the activating enzyme for NEDD8.

Walden H, Podgorski MS, Schulman BA.

Nature. 2003 Mar 20;422(6929):330-4.

PMID:
12646924
13.

Crystal structure of the human ubiquitin-activating enzyme 5 (UBA5) bound to ATP: mechanistic insights into a minimalistic E1 enzyme.

Bacik JP, Walker JR, Ali M, Schimmer AD, Dhe-Paganon S.

J Biol Chem. 2010 Jun 25;285(26):20273-80. doi: 10.1074/jbc.M110.102921. Epub 2010 Apr 5.

14.

Regulation of ubiquitin-conjugating enzymes by glutathione following oxidative stress.

Jahngen-Hodge J, Obin MS, Gong X, Shang F, Nowell TR Jr, Gong J, Abasi H, Blumberg J, Taylor A.

J Biol Chem. 1997 Nov 7;272(45):28218-26.

15.

Structural insights into E1-catalyzed ubiquitin activation and transfer to conjugating enzymes.

Lee I, Schindelin H.

Cell. 2008 Jul 25;134(2):268-78. doi: 10.1016/j.cell.2008.05.046.

16.

Demonstration of ubiquitin thiolester formation of UBE2Q2 (UBCi), a novel ubiquitin-conjugating enzyme with implantation site-specific expression.

Melner MH, Haas AL, Klein JM, Brash AR, Boeglin WE, Nagdas SK, Winfrey VP, Olson GE.

Biol Reprod. 2006 Sep;75(3):395-406. Epub 2006 Jun 7.

17.

Substrate properties of ubiquitin carboxyl-terminally derived peptide probes for protein ubiquitination.

Madden MM, Song W, Martell PG, Ren Y, Feng J, Lin Q.

Biochemistry. 2008 Mar 25;47(12):3636-44. doi: 10.1021/bi702078m. Epub 2008 Feb 29.

PMID:
18307316
18.

USE1 is a bispecific conjugating enzyme for ubiquitin and FAT10, which FAT10ylates itself in cis.

Aichem A, Pelzer C, Lukasiak S, Kalveram B, Sheppard PW, Rani N, Schmidtke G, Groettrup M.

Nat Commun. 2010 May 4;1:13. doi: 10.1038/ncomms1012.

PMID:
20975683
19.

Interferon-inducible ubiquitin E2, Ubc8, is a conjugating enzyme for protein ISGylation.

Kim KI, Giannakopoulos NV, Virgin HW, Zhang DE.

Mol Cell Biol. 2004 Nov;24(21):9592-600.

20.

The basis for selective E1-E2 interactions in the ISG15 conjugation system.

Durfee LA, Kelley ML, Huibregtse JM.

J Biol Chem. 2008 Aug 29;283(35):23895-902. doi: 10.1074/jbc.M804069200. Epub 2008 Jun 26.

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