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Results: 1 to 20 of 281

1.

Structure of C8alpha-MACPF reveals mechanism of membrane attack in complement immune defense.

Hadders MA, Beringer DX, Gros P.

Science. 2007 Sep 14;317(5844):1552-4.

PMID:
17872444
[PubMed - indexed for MEDLINE]
Free Article
2.

A common fold mediates vertebrate defense and bacterial attack.

Rosado CJ, Buckle AM, Law RH, Butcher RE, Kan WT, Bird CH, Ung K, Browne KA, Baran K, Bashtannyk-Puhalovich TA, Faux NG, Wong W, Porter CJ, Pike RN, Ellisdon AM, Pearce MC, Bottomley SP, Emsley J, Smith AI, Rossjohn J, Hartland EL, Voskoboinik I, Trapani JA, Bird PI, Dunstone MA, Whisstock JC.

Science. 2007 Sep 14;317(5844):1548-51. Epub 2007 Aug 23.

PMID:
17717151
[PubMed - indexed for MEDLINE]
Free Article
3.

Crystal structure of the MACPF domain of human complement protein C8 alpha in complex with the C8 gamma subunit.

Slade DJ, Lovelace LL, Chruszcz M, Minor W, Lebioda L, Sodetz JM.

J Mol Biol. 2008 May 30;379(2):331-42. doi: 10.1016/j.jmb.2008.03.061. Epub 2008 Apr 3.

PMID:
18440555
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Binding of human complement C8 to C9: role of the N-terminal modules in the C8 alpha subunit.

Scibek JJ, Plumb ME, Sodetz JM.

Biochemistry. 2002 Dec 10;41(49):14546-51.

PMID:
12463754
[PubMed - indexed for MEDLINE]
5.

Cholesterol-dependent cytolysins.

Gilbert RJ.

Adv Exp Med Biol. 2010;677:56-66. Review.

PMID:
20687480
[PubMed - indexed for MEDLINE]
6.

Incorporation of human complement C8 into the membrane attack complex is mediated by a binding site located within the C8beta MACPF domain.

Brannen CL, Sodetz JM.

Mol Immunol. 2007 Feb;44(5):960-5. Epub 2006 Apr 19.

PMID:
16624411
[PubMed - indexed for MEDLINE]
7.

Friend or foe: the same fold for attack and defense.

Lukoyanova N, Saibil HR.

Trends Immunol. 2008 Feb;29(2):51-3. doi: 10.1016/j.it.2007.11.003. Epub 2008 Jan 8. Review.

PMID:
18248850
[PubMed - indexed for MEDLINE]
8.

Structure of human C8 protein provides mechanistic insight into membrane pore formation by complement.

Lovelace LL, Cooper CL, Sodetz JM, Lebioda L.

J Biol Chem. 2011 May 20;286(20):17585-92. doi: 10.1074/jbc.M111.219766. Epub 2011 Mar 25.

PMID:
21454577
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Functional studies of the MACPF domain of human complement protein C8alpha reveal sites for simultaneous binding of C8beta, C8gamma, and C9.

Slade DJ, Chiswell B, Sodetz JM.

Biochemistry. 2006 Apr 25;45(16):5290-6.

PMID:
16618117
[PubMed - indexed for MEDLINE]
10.
11.

Membrane pore formation by human complement: functional importance of the transmembrane β-hairpin (TMH) segments of C8α and C9.

Weiland MH, Qian Y, Sodetz JM.

Mol Immunol. 2014 Feb;57(2):310-6. doi: 10.1016/j.molimm.2013.10.007. Epub 2013 Nov 12.

PMID:
24239861
[PubMed - indexed for MEDLINE]
12.

Structure of human complement C8, a precursor to membrane attack.

Bubeck D, Roversi P, Donev R, Morgan BP, Llorca O, Lea SM.

J Mol Biol. 2011 Jan 14;405(2):325-30. doi: 10.1016/j.jmb.2010.10.031. Epub 2010 Nov 10.

PMID:
21073882
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

The MACPF/CDC family of pore-forming toxins.

Rosado CJ, Kondos S, Bull TE, Kuiper MJ, Law RH, Buckle AM, Voskoboinik I, Bird PI, Trapani JA, Whisstock JC, Dunstone MA.

Cell Microbiol. 2008 Sep;10(9):1765-74. doi: 10.1111/j.1462-5822.2008.01191.x. Epub 2008 Jun 28. Review.

PMID:
18564372
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

The structure and function of mammalian membrane-attack complex/perforin-like proteins.

Kondos SC, Hatfaludi T, Voskoboinik I, Trapani JA, Law RH, Whisstock JC, Dunstone MA.

Tissue Antigens. 2010 Nov;76(5):341-51. doi: 10.1111/j.1399-0039.2010.01566.x. Epub 2010 Sep 22. Review.

PMID:
20860583
[PubMed - indexed for MEDLINE]
15.

Chimeric and truncated forms of human complement protein C8 alpha reveal binding sites for C8 beta and C8 gamma within the membrane attack complex/perforin region.

Plumb ME, Scibek JJ, Barber TD, Dunlap RJ, Platteborze PL, Sodetz JM.

Biochemistry. 1999 Jun 29;38(26):8478-84.

PMID:
10387094
[PubMed - indexed for MEDLINE]
16.

Crystal structure of complement protein C8gamma in complex with a peptide containing the C8gamma binding site on C8alpha: implications for C8gamma ligand binding.

Lovelace LL, Chiswell B, Slade DJ, Sodetz JM, Lebioda L.

Mol Immunol. 2008 Feb;45(3):750-6. Epub 2007 Aug 9.

PMID:
17692377
[PubMed - indexed for MEDLINE]
17.

Chlamydial homologues of the MACPF (MAC/perforin) domain.

Ponting CP.

Curr Biol. 1999 Dec 16-30;9(24):R911-3. Review. No abstract available.

PMID:
10608922
[PubMed - indexed for MEDLINE]
Free Article
18.

Membrane interactions and cellular effects of MACPF/CDC proteins.

Cajnko MM, Mikelj M, Turk T, Podobnik M, Anderluh G.

Subcell Biochem. 2014;80:119-44. doi: 10.1007/978-94-017-8881-6_7. Review.

PMID:
24798010
[PubMed - indexed for MEDLINE]
19.

Crystal structure of CD59: implications for molecular recognition of the complement proteins C8 and C9 in the membrane-attack complex.

Huang Y, Fedarovich A, Tomlinson S, Davies C.

Acta Crystallogr D Biol Crystallogr. 2007 Jun;63(Pt 6):714-21. Epub 2007 May 15.

PMID:
17505110
[PubMed - indexed for MEDLINE]
20.

Packing a punch: the mechanism of pore formation by cholesterol dependent cytolysins and membrane attack complex/perforin-like proteins.

Dunstone MA, Tweten RK.

Curr Opin Struct Biol. 2012 Jun;22(3):342-9. doi: 10.1016/j.sbi.2012.04.008. Epub 2012 May 31. Review.

PMID:
22658510
[PubMed - indexed for MEDLINE]
Free PMC Article

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