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Results: 1 to 20 of 105

1.

A role of the Lowe syndrome protein OCRL in early steps of the endocytic pathway.

Erdmann KS, Mao Y, McCrea HJ, Zoncu R, Lee S, Paradise S, Modregger J, Biemesderfer D, Toomre D, De Camilli P.

Dev Cell. 2007 Sep;13(3):377-90.

PMID:
17765681
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

All known patient mutations in the ASH-RhoGAP domains of OCRL affect targeting and APPL1 binding.

McCrea HJ, Paradise S, Tomasini L, Addis M, Melis MA, De Matteis MA, De Camilli P.

Biochem Biophys Res Commun. 2008 May 2;369(2):493-9. doi: 10.1016/j.bbrc.2008.02.067. Epub 2008 Feb 26.

PMID:
18307981
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Two closely related endocytic proteins that share a common OCRL-binding motif with APPL1.

Swan LE, Tomasini L, Pirruccello M, Lunardi J, De Camilli P.

Proc Natl Acad Sci U S A. 2010 Feb 23;107(8):3511-6. doi: 10.1073/pnas.0914658107. Epub 2010 Feb 2.

PMID:
20133602
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

A PH domain within OCRL bridges clathrin-mediated membrane trafficking to phosphoinositide metabolism.

Mao Y, Balkin DM, Zoncu R, Erdmann KS, Tomasini L, Hu F, Jin MM, Hodsdon ME, De Camilli P.

EMBO J. 2009 Jul 8;28(13):1831-42. doi: 10.1038/emboj.2009.155. Epub 2009 Jun 18.

PMID:
19536138
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

The inositol polyphosphate 5-phosphatase Ocrl associates with endosomes that are partially coated with clathrin.

Ungewickell A, Ward ME, Ungewickell E, Majerus PW.

Proc Natl Acad Sci U S A. 2004 Sep 14;101(37):13501-6. Epub 2004 Sep 7.

PMID:
15353600
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Recognition of the F&H motif by the Lowe syndrome protein OCRL.

Pirruccello M, Swan LE, Folta-Stogniew E, De Camilli P.

Nat Struct Mol Biol. 2011 Jun 12;18(7):789-95. doi: 10.1038/nsmb.2071.

PMID:
21666675
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Optogenetic control of phosphoinositide metabolism.

Idevall-Hagren O, Dickson EJ, Hille B, Toomre DK, De Camilli P.

Proc Natl Acad Sci U S A. 2012 Aug 28;109(35):E2316-23. doi: 10.1073/pnas.1211305109. Epub 2012 Jul 30.

PMID:
22847441
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Regulation of phagocytosis in Dictyostelium by the inositol 5-phosphatase OCRL homolog Dd5P4.

Loovers HM, Kortholt A, de Groote H, Whitty L, Nussbaum RL, van Haastert PJ.

Traffic. 2007 May;8(5):618-28. Epub 2007 Mar 2.

PMID:
17343681
[PubMed - indexed for MEDLINE]
9.

OCRL controls trafficking through early endosomes via PtdIns4,5P₂-dependent regulation of endosomal actin.

Vicinanza M, Di Campli A, Polishchuk E, Santoro M, Di Tullio G, Godi A, Levtchenko E, De Leo MG, Polishchuk R, Sandoval L, Marzolo MP, De Matteis MA.

EMBO J. 2011 Oct 4;30(24):4970-85. doi: 10.1038/emboj.2011.354.

PMID:
21971085
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

The association between the SH2-containing inositol polyphosphate 5-Phosphatase 2 (SHIP2) and the adaptor protein APS has an impact on biochemical properties of both partners.

Onnockx S, De Schutter J, Blockmans M, Xie J, Jacobs C, Vanderwinden JM, Erneux C, Pirson I.

J Cell Physiol. 2008 Jan;214(1):260-72.

PMID:
17620296
[PubMed - indexed for MEDLINE]
11.

Spatiotemporal control of endocytosis by phosphatidylinositol-3,4-bisphosphate.

Posor Y, Eichhorn-Gruenig M, Puchkov D, Schöneberg J, Ullrich A, Lampe A, Müller R, Zarbakhsh S, Gulluni F, Hirsch E, Krauss M, Schultz C, Schmoranzer J, Noé F, Haucke V.

Nature. 2013 Jul 11;499(7457):233-7. doi: 10.1038/nature12360. Epub 2013 Jul 3.

PMID:
23823722
[PubMed - indexed for MEDLINE]
12.

The 5-phosphatase OCRL mediates retrograde transport of the mannose 6-phosphate receptor by regulating a Rac1-cofilin signalling module.

van Rahden VA, Brand K, Najm J, Heeren J, Pfeffer SR, Braulke T, Kutsche K.

Hum Mol Genet. 2012 Dec 1;21(23):5019-38. doi: 10.1093/hmg/dds343. Epub 2012 Aug 19.

PMID:
22907655
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Structure and function of the Lowe syndrome protein OCRL1.

Lowe M.

Traffic. 2005 Sep;6(9):711-9. Review.

PMID:
16101675
[PubMed - indexed for MEDLINE]
14.

The synaptojanin-like protein Inp53/Sjl3 functions with clathrin in a yeast TGN-to-endosome pathway distinct from the GGA protein-dependent pathway.

Ha SA, Torabinejad J, DeWald DB, Wenk MR, Lucast L, De Camilli P, Newitt RA, Aebersold R, Nothwehr SF.

Mol Biol Cell. 2003 Apr;14(4):1319-33.

PMID:
12686590
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Cell lines from kidney proximal tubules of a patient with Lowe syndrome lack OCRL inositol polyphosphate 5-phosphatase and accumulate phosphatidylinositol 4,5-bisphosphate.

Zhang X, Hartz PA, Philip E, Racusen LC, Majerus PW.

J Biol Chem. 1998 Jan 16;273(3):1574-82.

PMID:
9430698
[PubMed - indexed for MEDLINE]
Free Article
16.

Recruitment of OCRL and Inpp5B to phagosomes by Rab5 and APPL1 depletes phosphoinositides and attenuates Akt signaling.

Bohdanowicz M, Balkin DM, De Camilli P, Grinstein S.

Mol Biol Cell. 2012 Jan;23(1):176-87. doi: 10.1091/mbc.E11-06-0489. Epub 2011 Nov 9.

PMID:
22072788
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Targeting of the type II inositol polyphosphate 5-phosphatase INPP5B to the early secretory pathway.

Williams C, Choudhury R, McKenzie E, Lowe M.

J Cell Sci. 2007 Nov 15;120(Pt 22):3941-51. Epub 2007 Oct 23.

PMID:
17956944
[PubMed - indexed for MEDLINE]
Free Article
18.

Loss of endocytic clathrin-coated pits upon acute depletion of phosphatidylinositol 4,5-bisphosphate.

Zoncu R, Perera RM, Sebastian R, Nakatsu F, Chen H, Balla T, Ayala G, Toomre D, De Camilli PV.

Proc Natl Acad Sci U S A. 2007 Mar 6;104(10):3793-8. Epub 2007 Feb 27.

PMID:
17360432
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Caenorhabditis elegans RME-6 is a novel regulator of RAB-5 at the clathrin-coated pit.

Sato M, Sato K, Fonarev P, Huang CJ, Liou W, Grant BD.

Nat Cell Biol. 2005 Jun;7(6):559-69. Epub 2005 May 15.

PMID:
15895077
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

A phosphoinositide switch controls the maturation and signaling properties of APPL endosomes.

Zoncu R, Perera RM, Balkin DM, Pirruccello M, Toomre D, De Camilli P.

Cell. 2009 Mar 20;136(6):1110-21. doi: 10.1016/j.cell.2009.01.032.

PMID:
19303853
[PubMed - indexed for MEDLINE]
Free PMC Article

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