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Items: 1 to 20 of 178

1.

Identification of TRAF6-dependent NEMO polyubiquitination sites through analysis of a new NEMO mutation causing incontinentia pigmenti.

Sebban-Benin H, Pescatore A, Fusco F, Pascuale V, Gautheron J, Yamaoka S, Moncla A, Ursini MV, Courtois G.

Hum Mol Genet. 2007 Dec 1;16(23):2805-15. Epub 2007 Aug 29. Erratum in: Hum Mol Genet. 2008 Feb 14;17(4):639.

2.

Identification of a new NEMO/TRAF6 interface affected in incontinentia pigmenti pathology.

Gautheron J, Pescatore A, Fusco F, Esposito E, Yamaoka S, Agou F, Ursini MV, Courtois G.

Hum Mol Genet. 2010 Aug 15;19(16):3138-49. doi: 10.1093/hmg/ddq222. Epub 2010 Jun 7.

3.

Skin lesion development in a mouse model of incontinentia pigmenti is triggered by NEMO deficiency in epidermal keratinocytes and requires TNF signaling.

Nenci A, Huth M, Funteh A, Schmidt-Supprian M, Bloch W, Metzger D, Chambon P, Rajewsky K, Krieg T, Haase I, Pasparakis M.

Hum Mol Genet. 2006 Feb 15;15(4):531-42. Epub 2006 Jan 6.

4.

Molecular analysis of the genetic defect in a large cohort of IP patients and identification of novel NEMO mutations interfering with NF-kappaB activation.

Fusco F, Bardaro T, Fimiani G, Mercadante V, Miano MG, Falco G, Israël A, Courtois G, D'Urso M, Ursini MV.

Hum Mol Genet. 2004 Aug 15;13(16):1763-73. Epub 2004 Jun 30.

6.

NESCA: a new NEMO/IKKgamma and TRAF6 interacting protein.

Napolitano G, Mirra S, Monfregola J, Lavorgna A, Leonardi A, Ursini MV.

J Cell Physiol. 2009 Aug;220(2):410-7. doi: 10.1002/jcp.21782.

PMID:
19365808
8.

A critical role of RICK/RIP2 polyubiquitination in Nod-induced NF-kappaB activation.

Hasegawa M, Fujimoto Y, Lucas PC, Nakano H, Fukase K, Núñez G, Inohara N.

EMBO J. 2008 Jan 23;27(2):373-83. Epub 2007 Dec 13.

9.

Lys63-linked polyubiquitination of IRAK-1 is required for interleukin-1 receptor- and toll-like receptor-mediated NF-kappaB activation.

Conze DB, Wu CJ, Thomas JA, Landstrom A, Ashwell JD.

Mol Cell Biol. 2008 May;28(10):3538-47. doi: 10.1128/MCB.02098-07. Epub 2008 Mar 17.

10.

NEMO, NFkappaB signaling and incontinentia pigmenti.

Nelson DL.

Curr Opin Genet Dev. 2006 Jun;16(3):282-8. Epub 2006 May 2. Review.

PMID:
16647846
11.

TRAF6 negatively regulates TNFalpha-induced NF-kappaB activation.

Funakoshi-Tago M, Kamada N, Shimizu T, Hashiguchi Y, Tago K, Sonoda Y, Kasahara T.

Cytokine. 2009 Feb;45(2):72-9. doi: 10.1016/j.cyto.2008.10.010. Epub 2008 Dec 16.

PMID:
19091594
12.

Malt1 ubiquitination triggers NF-kappaB signaling upon T-cell activation.

Oeckinghaus A, Wegener E, Welteke V, Ferch U, Arslan SC, Ruland J, Scheidereit C, Krappmann D.

EMBO J. 2007 Nov 14;26(22):4634-45. Epub 2007 Oct 18.

13.

Posttranslational modifications of NEMO and its partners in NF-kappaB signaling.

Sebban H, Yamaoka S, Courtois G.

Trends Cell Biol. 2006 Nov;16(11):569-77. Epub 2006 Sep 20. Review.

PMID:
16987664
14.

HSP27 regulates IL-1 stimulated IKK activation through interacting with TRAF6 and affecting its ubiquitination.

Wu Y, Liu J, Zhang Z, Huang H, Shen J, Zhang S, Jiang Y, Luo L, Yin Z.

Cell Signal. 2009 Jan;21(1):143-50. doi: 10.1016/j.cellsig.2008.10.001. Epub 2008 Oct 10.

PMID:
18950704
15.

Interleukin-1 (IL-1) induces the Lys63-linked polyubiquitination of IL-1 receptor-associated kinase 1 to facilitate NEMO binding and the activation of IkappaBalpha kinase.

Windheim M, Stafford M, Peggie M, Cohen P.

Mol Cell Biol. 2008 Mar;28(5):1783-91. doi: 10.1128/MCB.02380-06. Epub 2008 Jan 7.

16.

Sensing of Lys 63-linked polyubiquitination by NEMO is a key event in NF-kappaB activation [corrected].

Wu CJ, Conze DB, Li T, Srinivasula SM, Ashwell JD.

Nat Cell Biol. 2006 Apr;8(4):398-406. Epub 2006 Mar 19. Erratum in: Nat Cell Biol. 2006 Apr;8(4):424.

PMID:
16547522
17.

The NF-kappaB signalling pathway in human diseases: from incontinentia pigmenti to ectodermal dysplasias and immune-deficiency syndromes.

Smahi A, Courtois G, Rabia SH, Döffinger R, Bodemer C, Munnich A, Casanova JL, Israël A.

Hum Mol Genet. 2002 Oct 1;11(20):2371-5. Review.

18.

CARMA3 deficiency abrogates G protein-coupled receptor-induced NF-{kappa}B activation.

Grabiner BC, Blonska M, Lin PC, You Y, Wang D, Sun J, Darnay BG, Dong C, Lin X.

Genes Dev. 2007 Apr 15;21(8):984-96.

19.

Novel insights into the cellular mechanisms of the anti-inflammatory effects of NF-kappaB essential modulator binding domain peptides.

Baima ET, Guzova JA, Mathialagan S, Nagiec EE, Hardy MM, Song LR, Bonar SL, Weinberg RA, Selness SR, Woodard SS, Chrencik J, Hood WF, Schindler JF, Kishore N, Mbalaviele G.

J Biol Chem. 2010 Apr 30;285(18):13498-506. doi: 10.1074/jbc.M109.099895. Epub 2010 Feb 18.

20.

Activation of noncanonical NF-kappaB signaling by the oncoprotein Tio.

de Jong SJ, Albrecht JC, Schmidt M, Müller-Fleckenstein I, Biesinger B.

J Biol Chem. 2010 May 28;285(22):16495-503. doi: 10.1074/jbc.M110.102848. Epub 2010 Mar 30.

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