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Transient limb ischemia induces remote preconditioning and remote postconditioning in humans by a K(ATP)-channel dependent mechanism.

Loukogeorgakis SP, Williams R, Panagiotidou AT, Kolvekar SK, Donald A, Cole TJ, Yellon DM, Deanfield JE, MacAllister RJ.

Circulation. 2007 Sep 18;116(12):1386-95. Epub 2007 Aug 27.


Remote ischemic preconditioning provides early and late protection against endothelial ischemia-reperfusion injury in humans: role of the autonomic nervous system.

Loukogeorgakis SP, Panagiotidou AT, Broadhead MW, Donald A, Deanfield JE, MacAllister RJ.

J Am Coll Cardiol. 2005 Aug 2;46(3):450-6.


Postconditioning protects against endothelial ischemia-reperfusion injury in the human forearm.

Loukogeorgakis SP, Panagiotidou AT, Yellon DM, Deanfield JE, MacAllister RJ.

Circulation. 2006 Feb 21;113(7):1015-9. Epub 2006 Feb 13.


Transient limb ischemia induces remote ischemic preconditioning in vivo.

Kharbanda RK, Mortensen UM, White PA, Kristiansen SB, Schmidt MR, Hoschtitzky JA, Vogel M, Sorensen K, Redington AN, MacAllister R.

Circulation. 2002 Dec 3;106(23):2881-3.


Postconditioning protects against human endothelial ischaemia-reperfusion injury via subtype-specific KATP channel activation and is mimicked by inhibition of the mitochondrial permeability transition pore.

Okorie MI, Bhavsar DD, Ridout D, Charakida M, Deanfield JE, Loukogeorgakis SP, MacAllister RJ.

Eur Heart J. 2011 May;32(10):1266-74. doi: 10.1093/eurheartj/ehr041. Epub 2011 Feb 28.


KATP channel activation induces ischemic preconditioning of the endothelium in humans in vivo.

Broadhead MW, Kharbanda RK, Peters MJ, MacAllister RJ.

Circulation. 2004 Oct 12;110(15):2077-82. Epub 2004 Oct 4.


Ischemic preconditioning prevents endothelial injury and systemic neutrophil activation during ischemia-reperfusion in humans in vivo.

Kharbanda RK, Peters M, Walton B, Kattenhorn M, Mullen M, Klein N, Vallance P, Deanfield J, MacAllister R.

Circulation. 2001 Mar 27;103(12):1624-30.


Remote ischemic preconditioning: a novel protective method from ischemia reperfusion injury--a review.

Tapuria N, Kumar Y, Habib MM, Abu Amara M, Seifalian AM, Davidson BR.

J Surg Res. 2008 Dec;150(2):304-30. doi: 10.1016/j.jss.2007.12.747. Epub 2008 Jan 22. Review.


Preventive effects of exenatide on endothelial dysfunction induced by ischemia-reperfusion injury via KATP channels.

Ha SJ, Kim W, Woo JS, Kim JB, Kim SJ, Kim WS, Kim MK, Cheng XW, Kim KS.

Arterioscler Thromb Vasc Biol. 2012 Feb;32(2):474-80. doi: 10.1161/ATVBAHA.110.222653. Epub 2011 Dec 8.


Protective effect of remote ischemic preconditioning in renal ischemia/reperfusion injury, in a model of thoracoabdominal aorta approach.

Lazaris AM, Maheras AN, Vasdekis SN, Karkaletsis KG, Charalambopoulos A, Kakisis JD, Martikos G, Patapis P, Giamarellos-Bourboulis EJ, Karatzas GM, Liakakos TD.

J Surg Res. 2009 Jun 15;154(2):267-73. doi: 10.1016/j.jss.2008.06.037. Epub 2008 Jul 26.


Remote ischemic preconditioning of the recipient reduces myocardial ischemia-reperfusion injury of the denervated donor heart via a Katp channel-dependent mechanism.

Konstantinov IE, Li J, Cheung MM, Shimizu M, Stokoe J, Kharbanda RK, Redington AN.

Transplantation. 2005 Jun 27;79(12):1691-5.


Remote ischemic preconditioning prevents reduction in brachial artery flow-mediated dilation after strenuous exercise.

Bailey TG, Birk GK, Cable NT, Atkinson G, Green DJ, Jones H, Thijssen DH.

Am J Physiol Heart Circ Physiol. 2012 Sep 1;303(5):H533-8. doi: 10.1152/ajpheart.00272.2012. Epub 2012 Jun 22.


Daily ischemic preconditioning provides sustained protection from ischemia-reperfusion induced endothelial dysfunction: a human study.

Luca MC, Liuni A, McLaughlin K, Gori T, Parker JD.

J Am Heart Assoc. 2013 Feb 22;2(1):e000075. doi: 10.1161/JAHA.112.000075.


Role of endothelial nitric oxide synthase in remote ischemic preconditioning of the mouse liver.

Abu-Amara M, Yang SY, Quaglia A, Rowley P, Fuller B, Seifalian A, Davidson B.

Liver Transpl. 2011 May;17(5):610-9. doi: 10.1002/lt.22272.


Limb remote ischemic preconditioning protects the spinal cord from ischemia-reperfusion injury: a newly identified nonneuronal but reactive oxygen species-dependent pathway.

Dong HL, Zhang Y, Su BX, Zhu ZH, Gu QH, Sang HF, Xiong L.

Anesthesiology. 2010 Apr;112(4):881-91. doi: 10.1097/ALN.0b013e3181d0486d.


Aldehyde dehydrogenase-2 inhibition blocks remote preconditioning in experimental and human models.

Contractor H, Støttrup NB, Cunnington C, Manlhiot C, Diesch J, Ormerod JO, Jensen R, Bøtker HE, Redington A, Schmidt MR, Ashrafian H, Kharbanda RK.

Basic Res Cardiol. 2013 May;108(3):343. doi: 10.1007/s00395-013-0343-3. Epub 2013 Mar 24.


The hepatic soluble guanylyl cyclase-cyclic guanosine monophosphate pathway mediates the protection of remote ischemic preconditioning on the microcirculation in liver ischemia-reperfusion injury.

Abu-Amara M, Yang SY, Quaglia A, Rowley P, Tapuria N, Fuller B, Davidson B, Seifalian A.

Transplantation. 2012 May 15;93(9):880-6. doi: 10.1097/TP.0b013e31824cd59d.


Randomized controlled trial of the effects of remote ischemic preconditioning on children undergoing cardiac surgery: first clinical application in humans.

Cheung MM, Kharbanda RK, Konstantinov IE, Shimizu M, Frndova H, Li J, Holtby HM, Cox PN, Smallhorn JF, Van Arsdell GS, Redington AN.

J Am Coll Cardiol. 2006 Jun 6;47(11):2277-82. Epub 2006 May 15.

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