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Results: 1 to 20 of 171

1.

Werner syndrome protein interacts functionally with translesion DNA polymerases.

Kamath-Loeb AS, Lan L, Nakajima S, Yasui A, Loeb LA.

Proc Natl Acad Sci U S A. 2007 Jun 19;104(25):10394-9. Epub 2007 Jun 11.

PMID:
17563354
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

WRN interacts physically and functionally with the recombination mediator protein RAD52.

Baynton K, Otterlei M, Bjørås M, von Kobbe C, Bohr VA, Seeberg E.

J Biol Chem. 2003 Sep 19;278(38):36476-86. Epub 2003 May 15.

PMID:
12750383
[PubMed - indexed for MEDLINE]
Free Article
3.

The RecQ helicase WRN is required for normal replication fork progression after DNA damage or replication fork arrest.

Sidorova JM, Li N, Folch A, Monnat RJ Jr.

Cell Cycle. 2008 Mar 15;7(6):796-807. Epub 2008 Jan 4.

PMID:
18250621
[PubMed - indexed for MEDLINE]
Free Article
4.

Interaction with DNA polymerase eta is required for nuclear accumulation of REV1 and suppression of spontaneous mutations in human cells.

Akagi J, Masutani C, Kataoka Y, Kan T, Ohashi E, Mori T, Ohmori H, Hanaoka F.

DNA Repair (Amst). 2009 May 1;8(5):585-99. doi: 10.1016/j.dnarep.2008.12.006. Epub 2009 Jan 21.

PMID:
19157994
[PubMed - indexed for MEDLINE]
5.

Nuclear DNA helicase II (RNA helicase A) interacts with Werner syndrome helicase and stimulates its exonuclease activity.

Friedemann J, Grosse F, Zhang S.

J Biol Chem. 2005 Sep 2;280(35):31303-13. Epub 2005 Jul 1.

PMID:
15995249
[PubMed - indexed for MEDLINE]
Free Article
6.

The Werner syndrome protein functions in repair of Cr(VI)-induced replication-associated DNA damage.

Liu FJ, Barchowsky A, Opresko PL.

Toxicol Sci. 2009 Aug;110(2):307-18. doi: 10.1093/toxsci/kfp104. Epub 2009 Jun 1.

PMID:
19487340
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

The Werner syndrome protein is required for recruitment of chromatin assembly factor 1 following DNA damage.

Jiao R, Harrigan JA, Shevelev I, Dietschy T, Selak N, Indig FE, Piotrowski J, Janscak P, Bohr VA, Stagljar I.

Oncogene. 2007 May 31;26(26):3811-22. Epub 2006 Dec 18.

PMID:
17173071
[PubMed - indexed for MEDLINE]
8.

The Werner syndrome protein confers resistance to the DNA lesions N3-methyladenine and O6-methylguanine: implications for WRN function.

Blank A, Bobola MS, Gold B, Varadarajan S, D Kolstoe D, Meade EH, Rabinovitch PS, Loeb LA, Silber JR.

DNA Repair (Amst). 2004 Jun 3;3(6):629-38.

PMID:
15135730
[PubMed - indexed for MEDLINE]
9.

Enzymatic mechanism of the WRN helicase/nuclease.

Brosh RM Jr, Opresko PL, Bohr VA.

Methods Enzymol. 2006;409:52-85.

PMID:
16793395
[PubMed - indexed for MEDLINE]
10.

Functional interaction between the Werner Syndrome protein and DNA polymerase delta.

Kamath-Loeb AS, Johansson E, Burgers PM, Loeb LA.

Proc Natl Acad Sci U S A. 2000 Apr 25;97(9):4603-8.

PMID:
10781066
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Poly(ADP-ribose) polymerase 1 regulates both the exonuclease and helicase activities of the Werner syndrome protein.

von Kobbe C, Harrigan JA, Schreiber V, Stiegler P, Piotrowski J, Dawut L, Bohr VA.

Nucleic Acids Res. 2004 Aug 3;32(13):4003-14. Print 2004.

PMID:
15292449
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Werner protein stimulates topoisomerase I DNA relaxation activity.

Laine JP, Opresko PL, Indig FE, Harrigan JA, von Kobbe C, Bohr VA.

Cancer Res. 2003 Nov 1;63(21):7136-46.

PMID:
14612507
[PubMed - indexed for MEDLINE]
Free Article
13.

Human DNA polymerase eta promotes DNA synthesis from strand invasion intermediates of homologous recombination.

McIlwraith MJ, Vaisman A, Liu Y, Fanning E, Woodgate R, West SC.

Mol Cell. 2005 Dec 9;20(5):783-92. Erratum in: Mol Cell. 2006 Feb 3;21(3):445. Mcllwraith, Michael J [corrected to McIlwraith, Michael J].

PMID:
16337601
[PubMed - indexed for MEDLINE]
Free Article
14.

WRN participates in translesion synthesis pathway through interaction with NBS1.

Kobayashi J, Okui M, Asaithamby A, Burma S, Chen BP, Tanimoto K, Matsuura S, Komatsu K, Chen DJ.

Mech Ageing Dev. 2010 Jun;131(6):436-44. doi: 10.1016/j.mad.2010.06.005. Epub 2010 Jun 17.

PMID:
20600238
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

p53 modulates RPA-dependent and RPA-independent WRN helicase activity.

Sommers JA, Sharma S, Doherty KM, Karmakar P, Yang Q, Kenny MK, Harris CC, Brosh RM Jr.

Cancer Res. 2005 Feb 15;65(4):1223-33.

PMID:
15735006
[PubMed - indexed for MEDLINE]
Free Article
16.

Werner syndrome protein participates in a complex with RAD51, RAD54, RAD54B and ATR in response to ICL-induced replication arrest.

Otterlei M, Bruheim P, Ahn B, Bussen W, Karmakar P, Baynton K, Bohr VA.

J Cell Sci. 2006 Dec 15;119(Pt 24):5137-46. Epub 2006 Nov 21. Erratum in: J Cell Sci. 2006 Dec 15;119(Pt 24):5215.

PMID:
17118963
[PubMed - indexed for MEDLINE]
Free Article
17.

Functional role of the Werner syndrome RecQ helicase in human fibroblasts.

Dhillon KK, Sidorova J, Saintigny Y, Poot M, Gollahon K, Rabinovitch PS, Monnat RJ Jr.

Aging Cell. 2007 Feb;6(1):53-61.

PMID:
17266675
[PubMed - indexed for MEDLINE]
Free Article
18.

The Werner and Bloom syndrome proteins catalyze regression of a model replication fork.

Machwe A, Xiao L, Groden J, Orren DK.

Biochemistry. 2006 Nov 28;45(47):13939-46.

PMID:
17115688
[PubMed - indexed for MEDLINE]
19.

Accumulation of Werner protein at DNA double-strand breaks in human cells.

Lan L, Nakajima S, Komatsu K, Nussenzweig A, Shimamoto A, Oshima J, Yasui A.

J Cell Sci. 2005 Sep 15;118(Pt 18):4153-62. Epub 2005 Sep 1.

PMID:
16141234
[PubMed - indexed for MEDLINE]
Free Article
20.

The Werner syndrome helicase is a cofactor for HIV-1 long terminal repeat transactivation and retroviral replication.

Sharma A, Awasthi S, Harrod CK, Matlock EF, Khan S, Xu L, Chan S, Yang H, Thammavaram CK, Rasor RA, Burns DK, Skiest DJ, Van Lint C, Girard AM, McGee M, Monnat RJ Jr, Harrod R.

J Biol Chem. 2007 Apr 20;282(16):12048-57. Epub 2007 Feb 21.

PMID:
17317667
[PubMed - indexed for MEDLINE]
Free Article

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