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Items: 1 to 20 of 236

1.

Two novel imatinib-responsive PDGFRA fusion genes in chronic eosinophilic leukaemia.

Curtis CE, Grand FH, Musto P, Clark A, Murphy J, Perla G, Minervini MM, Stewart J, Reiter A, Cross NC.

Br J Haematol. 2007 Jul;138(1):77-81.

PMID:
17555450
2.

Transient response to imatinib in a chronic eosinophilic leukemia associated with ins(9;4)(q33;q12q25) and a CDK5RAP2-PDGFRA fusion gene.

Walz C, Curtis C, Schnittger S, Schultheis B, Metzgeroth G, Schoch C, Lengfelder E, Erben P, Müller MC, Haferlach T, Hochhaus A, Hehlmann R, Cross NC, Reiter A.

Genes Chromosomes Cancer. 2006 Oct;45(10):950-6.

PMID:
16845659
3.

Identification of a novel imatinib responsive KIF5B-PDGFRA fusion gene following screening for PDGFRA overexpression in patients with hypereosinophilia.

Score J, Curtis C, Waghorn K, Stalder M, Jotterand M, Grand FH, Cross NC.

Leukemia. 2006 May;20(5):827-32.

PMID:
16498388
4.

The hypereosinophilic syndrome: fluorescence in situ hybridization detects the del(4)(q12)-FIP1L1/PDGFRA but not genomic rearrangements of other tyrosine kinases.

La Starza R, Specchia G, Cuneo A, Beacci D, Nozzoli C, Luciano L, Aventin A, Sambani C, Testoni N, Foppoli M, Invernizzi R, Marynen P, Martelli MF, Mecucci C.

Haematologica. 2005 May;90(5):596-601.

5.

FIP1L1-PDGFRalpha alone or with other genetic abnormalities reveals disease progression in chronic eosinophilic leukemia but good response to imatinib.

Wang LN, Pan Q, Fu JF, Shi JY, Jin J, Li JM, Hu J, Zhao WL, Chen Z, Chen SJ.

Chin Med J (Engl). 2008 May 20;121(10):867-73.

PMID:
18706197
6.

CHIC2 deletion, a surrogate for FIP1L1-PDGFRA fusion, occurs in systemic mastocytosis associated with eosinophilia and predicts response to imatinib mesylate therapy.

Pardanani A, Ketterling RP, Brockman SR, Flynn HC, Paternoster SF, Shearer BM, Reeder TL, Li CY, Cross NC, Cools J, Gilliland DG, Dewald GW, Tefferi A.

Blood. 2003 Nov 1;102(9):3093-6. Epub 2003 Jul 3.

7.

Safety and efficacy of imatinib in chronic eosinophilic leukaemia and hypereosinophilic syndrome: a phase-II study.

Metzgeroth G, Walz C, Erben P, Popp H, Schmitt-Graeff A, Haferlach C, Fabarius A, Schnittger S, Grimwade D, Cross NC, Hehlmann R, Hochhaus A, Reiter A.

Br J Haematol. 2008 Dec;143(5):707-15. doi: 10.1111/j.1365-2141.2008.07294.x. Epub 2008 Oct 17.

PMID:
18950453
8.

Successful imatinib treatment of cardiac involvement of FIP1L1-PDGFRA-positive chronic eosinophilic leukemia followed by severe hepatotoxicity.

Arai A, Yan W, Wakabayashi S, Hayashi S, Inazawa J, Miura O.

Int J Hematol. 2007 Oct;86(3):233-7. Review.

PMID:
17988989
9.

Detection of FIP1L1-PDGFRA fusion by FISH.

Ma ES, Wong KF, Wong CL, Siu LL.

Br J Haematol. 2007 Aug;138(3):279. Epub 2007 Jun 3. No abstract available.

PMID:
17542982
10.

The FIP1L1-PDGFRalpha fusion tyrosine kinase in hypereosinophilic syndrome and chronic eosinophilic leukemia: implications for diagnosis, classification, and management.

Gotlib J, Cools J, Malone JM 3rd, Schrier SL, Gilliland DG, Coutré SE.

Blood. 2004 Apr 15;103(8):2879-91. Epub 2003 Nov 20. Review.

11.

FIP1L1-PDGFR alpha, a therapeutic target for the treatment of chronic eosinophilic leukemia.

Cools J.

Verh K Acad Geneeskd Belg. 2005;67(3):169-76. Review.

PMID:
16089297
12.

A single weekly dose of imatinib is sufficient to induce and maintain remission of chronic eosinophilic leukaemia in FIP1L1-PDGFRA-expressing patients.

Helbig G, Stella-Hołowiecka B, Majewski M, Całbecka M, Gajkowska J, Klimkiewicz R, Moskwa A, Grzegorczyk J, Lewandowska M, Hołowiecki J.

Br J Haematol. 2008 Apr;141(2):200-4. doi: 10.1111/j.1365-2141.2008.07033.x. Epub 2008 Feb 26.

PMID:
18307562
13.

Low-dose imatinib mesylate leads to rapid induction of major molecular responses and achievement of complete molecular remission in FIP1L1-PDGFRA-positive chronic eosinophilic leukemia.

Jovanovic JV, Score J, Waghorn K, Cilloni D, Gottardi E, Metzgeroth G, Erben P, Popp H, Walz C, Hochhaus A, Roche-Lestienne C, Preudhomme C, Solomon E, Apperley J, Rondoni M, Ottaviani E, Martinelli G, Brito-Babapulle F, Saglio G, Hehlmann R, Cross NC, Reiter A, Grimwade D.

Blood. 2007 Jun 1;109(11):4635-40. Epub 2007 Feb 13.

14.

Rapid reversal of quadraparesis in chronic eosinophilic leukaemia expressing the FIP1L1-PDGFRA transcript after therapy with imatinib.

Hus M, Helbig G, Cioch M, Szczepanska-Szerej H, Wieczorek P, Woźniak M, Kozinska J, Morawska M, Dmoszynska A, Kyrcz-Krzemien S, Kata D.

Leuk Res. 2011 Mar;35(3):e15-7. doi: 10.1016/j.leukres.2010.10.026. Epub 2010 Nov 18. No abstract available.

PMID:
21093052
15.

Clinical and molecular features of FIP1L1-PDFGRA (+) chronic eosinophilic leukemias.

Vandenberghe P, Wlodarska I, Michaux L, Zachée P, Boogaerts M, Vanstraelen D, Herregods MC, Van Hoof A, Selleslag D, Roufosse F, Maerevoet M, Verhoef G, Cools J, Gilliland DG, Hagemeijer A, Marynen P.

Leukemia. 2004 Apr;18(4):734-42.

PMID:
14973504
16.

Weekly imatinib dosage for chronic eosinophilic leukaemia expressing FIP1L1-PDGFRA fusion transcript: extended follow-up.

Helbig G, Moskwa A, Swiderska A, Urbanowicz A, Całbecka M, Gajkowska J, Zdziarska B, Brzeźniakiewicz K, Pogrzeba J, Krzemień S.

Br J Haematol. 2009 Apr;145(1):132-4. doi: 10.1111/j.1365-2141.2008.07546.x. Epub 2008 Dec 20. No abstract available.

PMID:
19120352
17.

[A man with FIP1L1/PDGFRA-positive chronic eosinophilic leukemia].

Leeksma OC, de Ruiter GS, van der Hulst VP, Terpstra WE, Cools J, Vandenberghe P.

Ned Tijdschr Geneeskd. 2006 Sep 2;150(35):1936-43. Dutch.

PMID:
16999279
18.

PDGFRalpha/FIP1L1-positive chronic eosinophilic leukemia presenting with retro-orbital localization: efficacy of imatinib treatment.

Vigna E, Lucia E, Gentile M, Mazzone C, Bisconte MG, Gentile C, Armentano A, Ottaviani E, Rondoni M, Martinelli G, Morabito F.

Cancer Chemother Pharmacol. 2008 Apr;61(4):713-6. Epub 2007 Jun 5.

PMID:
17549478
19.

A novel FIP1L1-PDGFRA mutant destabilizing the inactive conformation of the kinase domain in chronic eosinophilic leukemia/hypereosinophilic syndrome.

Salemi S, Yousefi S, Simon D, Schmid I, Moretti L, Scapozza L, Simon HU.

Allergy. 2009 Jun;64(6):913-8. doi: 10.1111/j.1398-9995.2009.01943.x. Epub 2009 Feb 7.

20.

FIP1L1-PDGFRA positive chronic eosinophilic leukaemia and associated central nervous system involvement.

Williams C, Kalra S, Nath U, Bown N, Wilson V, Wilkins BS, Neylon AJ.

J Clin Pathol. 2008 May;61(5):677-80. doi: 10.1136/jcp.2007.052100. Epub 2008 Feb 6.

PMID:
18256119
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