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Results: 1 to 20 of 192

1.

Wilms tumor suppressor WTX negatively regulates WNT/beta-catenin signaling.

Major MB, Camp ND, Berndt JD, Yi X, Goldenberg SJ, Hubbert C, Biechele TL, Gingras AC, Zheng N, Maccoss MJ, Angers S, Moon RT.

Science. 2007 May 18;316(5827):1043-6.

PMID:
17510365
[PubMed - indexed for MEDLINE]
Free Article
2.

Cancer. Converging on beta-catenin in Wilms tumor.

Nusse R.

Science. 2007 May 18;316(5827):988-9. No abstract available.

PMID:
17510350
[PubMed - indexed for MEDLINE]
3.

Structural and functional characterization of the Wnt inhibitor APC membrane recruitment 1 (Amer1).

Tanneberger K, Pfister AS, Kriz V, Bryja V, Schambony A, Behrens J.

J Biol Chem. 2011 Jun 3;286(22):19204-14. doi: 10.1074/jbc.M111.224881. Epub 2011 Apr 15.

PMID:
21498506
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Adenomatous polyposis coli (APC) membrane recruitment 3, a member of the APC membrane recruitment family of APC-binding proteins, is a positive regulator of Wnt-β-catenin signalling.

Brauburger K, Akyildiz S, Ruppert JG, Graeb M, Bernkopf DB, Hadjihannas MV, Behrens J.

FEBS J. 2014 Feb;281(3):787-801. doi: 10.1111/febs.12624. Epub 2013 Dec 12.

PMID:
24251807
[PubMed - indexed for MEDLINE]
5.

Amer2 protein is a novel negative regulator of Wnt/β-catenin signaling involved in neuroectodermal patterning.

Pfister AS, Tanneberger K, Schambony A, Behrens J.

J Biol Chem. 2012 Jan 13;287(3):1734-41. doi: 10.1074/jbc.M111.308650. Epub 2011 Nov 28.

PMID:
22128170
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

The ubiquitin-specific protease USP34 regulates axin stability and Wnt/β-catenin signaling.

Lui TT, Lacroix C, Ahmed SM, Goldenberg SJ, Leach CA, Daulat AM, Angers S.

Mol Cell Biol. 2011 May;31(10):2053-65. doi: 10.1128/MCB.01094-10. Epub 2011 Mar 7.

PMID:
21383061
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Wilms tumor gene on X chromosome (WTX) inhibits degradation of NRF2 protein through competitive binding to KEAP1 protein.

Camp ND, James RG, Dawson DW, Yan F, Davison JM, Houck SA, Tang X, Zheng N, Major MB, Moon RT.

J Biol Chem. 2012 Feb 24;287(9):6539-50. doi: 10.1074/jbc.M111.316471. Epub 2012 Jan 3.

PMID:
22215675
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Mutational analysis of WTX gene in Wnt/ beta-catenin pathway in gastric, colorectal, and hepatocellular carcinomas.

Yoo NJ, Kim S, Lee SH.

Dig Dis Sci. 2009 May;54(5):1011-4. doi: 10.1007/s10620-008-0458-9. Epub 2008 Aug 22.

PMID:
18720004
[PubMed - indexed for MEDLINE]
9.

Prickle-1 negatively regulates Wnt/beta-catenin pathway by promoting Dishevelled ubiquitination/degradation in liver cancer.

Chan DW, Chan CY, Yam JW, Ching YP, Ng IO.

Gastroenterology. 2006 Oct;131(4):1218-27. Epub 2006 Jul 24.

PMID:
17030191
[PubMed - indexed for MEDLINE]
10.

The KLHL12-Cullin-3 ubiquitin ligase negatively regulates the Wnt-beta-catenin pathway by targeting Dishevelled for degradation.

Angers S, Thorpe CJ, Biechele TL, Goldenberg SJ, Zheng N, MacCoss MJ, Moon RT.

Nat Cell Biol. 2006 Apr;8(4):348-57. Epub 2006 Mar 19.

PMID:
16547521
[PubMed - indexed for MEDLINE]
11.

Canonical WNT signalling determines lineage specificity in Wilms tumour.

Fukuzawa R, Anaka MR, Weeks RJ, Morison IM, Reeve AE.

Oncogene. 2009 Feb 26;28(8):1063-75. doi: 10.1038/onc.2008.455. Epub 2009 Jan 12.

PMID:
19137020
[PubMed - indexed for MEDLINE]
12.

LMP1 antagonizes WNT/β-catenin signalling through inhibition of WTX and promotes nasopharyngeal dysplasia but not tumourigenesis in LMP1(B95-8) transgenic mice.

QingLing Z, LiNa Y, Li L, Shuang W, YuFang Y, Yi D, Divakaran J, Xin L, YanQing D.

J Pathol. 2011 Apr;223(5):574-83. doi: 10.1002/path.2820. Epub 2010 Dec 10.

PMID:
21394719
[PubMed - indexed for MEDLINE]
13.

Inactivation of the APC gene is constant in adrenocortical tumors from patients with familial adenomatous polyposis but not frequent in sporadic adrenocortical cancers.

Gaujoux S, Pinson S, Gimenez-Roqueplo AP, Amar L, Ragazzon B, Launay P, Meatchi T, Libé R, Bertagna X, Audebourg A, Zucman-Rossi J, Tissier F, Bertherat J.

Clin Cancer Res. 2010 Nov 1;16(21):5133-41. doi: 10.1158/1078-0432.CCR-10-1497. Epub 2010 Oct 26.

PMID:
20978149
[PubMed - indexed for MEDLINE]
Free Article
14.

Direct ubiquitination of beta-catenin by Siah-1 and regulation by the exchange factor TBL1.

Dimitrova YN, Li J, Lee YT, Rios-Esteves J, Friedman DB, Choi HJ, Weis WI, Wang CY, Chazin WJ.

J Biol Chem. 2010 Apr 30;285(18):13507-16. doi: 10.1074/jbc.M109.049411. Epub 2010 Feb 24. Erratum in: J Biol Chem. 2010 Jun 25;285(26):20422.

PMID:
20181957
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Signaling through beta-catenin and Lef/Tcf.

Novak A, Dedhar S.

Cell Mol Life Sci. 1999 Oct 30;56(5-6):523-37. Review.

PMID:
11212302
[PubMed - indexed for MEDLINE]
16.

[Mechanism of Wnt signaling pathway regulation by a truncated mutant of Axin2 in colorectal cancer].

Wang FW, Wen L, Zhu SW, Yao Q, Cai YM, Ma G.

Ai Zheng. 2007 Oct;26(10):1041-6. Chinese.

PMID:
17927870
[PubMed - indexed for MEDLINE]
17.

Shared molecular mechanisms regulate multiple catenin proteins: canonical Wnt signals and components modulate p120-catenin isoform-1 and additional p120 subfamily members.

Hong JY, Park JI, Cho K, Gu D, Ji H, Artandi SE, McCrea PD.

J Cell Sci. 2010 Dec 15;123(Pt 24):4351-65. doi: 10.1242/jcs.067199. Epub 2010 Nov 23.

PMID:
21098636
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Interaction among GSK-3, GBP, axin, and APC in Xenopus axis specification.

Farr GH 3rd, Ferkey DM, Yost C, Pierce SB, Weaver C, Kimelman D.

J Cell Biol. 2000 Feb 21;148(4):691-702.

PMID:
10684251
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Deregulation of Wnt/β-catenin signaling through genetic or epigenetic alterations in human neuroendocrine tumors.

Kim JT, Li J, Jang ER, Gulhati P, Rychahou PG, Napier DL, Wang C, Weiss HL, Lee EY, Anthony L, Townsend CM Jr, Liu C, Evers BM.

Carcinogenesis. 2013 May;34(5):953-61. doi: 10.1093/carcin/bgt018. Epub 2013 Jan 25.

PMID:
23354304
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

The roles of APC and Axin derived from experimental and theoretical analysis of the Wnt pathway.

Lee E, Salic A, Krüger R, Heinrich R, Kirschner MW.

PLoS Biol. 2003 Oct;1(1):E10. Epub 2003 Oct 13. Erratum in: PLoS Biol. 2004 Mar;2(3):E89.

PMID:
14551908
[PubMed - indexed for MEDLINE]
Free PMC Article

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