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17489851,16954950,14526128,17003641,18076731,15987793,12939655,11938439,22094894,12825076,19593166,20551465,19944211,15567996,17613931,25003218,12853682,18206817,19951905,22427236,18580441,10950058,19812525,11462247,23751316,20502448,12529713,11355022,25835118,12014716,19404200,12759680,17981921,17681820,17204147,15800694,17446841,25981744,16823394,12952861,16497624,21520337,27578509,18953248,11866271,18522894,15082592,16134171,12120220,18852684,11775491,21323990,17662673,21415673,25206283,22158025,18511571,15764155,15980664,14641934,14695529,16632097,15775704,17575549,15528018,10835640,19287144,18272034,18986377,15241793,10653140,15528021,9435322,19657220,20977904,22699143,19052022,15233679,26658045,29173301,19888199,16958672,15784035,20676769,11950817,26100556,21303407,16714368,15329520,12218938,15749233,22228370,18992954,17148697,17609059,18286680,15749232,20720446,10571949,17877132,14998948,15307877,16111090,21673536,18617776,24217635,15528017,22580415,10671922,17238030,16429425,16632093,18663346,18810634,12743777,12560855,17242497,16492714,16981266,19453252,11753798,11810271,26692446,15151509,24616641,20625975,30134826,16423550,24909264,11729110,17111846,12634855,10909845,10668931,11354633,15749231,19077465,19565042,17716958,18178635,11916201,18702646,27171515,16187186,18782298,11569691,20664488,22020151,15725720,19717257,16354799,10980579,15870824,24451227,16412743,18703181,26348468,15957615,14688470,23951356,12120222,20510827,16572913,17015492,18360295,17120980,30420730,16678395,15463907,20387681,15528020,16083720,22109105,24002981,32669225,11708864,10989979,17163998,12360463,25383785,27941194,17123529,15650287,17331079,17761461,16427927,16786510,16457214,19454815,25869325,24440239,11073713,18755888,24134754,15910626,18955805,29641165,17254580,19202204,12828958,16837250,27673710,14586256,19181743,15533353,18090235,17572159,26822915,19886063,11143296,18301294,17594398,36883543,10982968,19844201,27179762,11062709,12658399,18955007,19550412,24844923,15655684,23092102,19077469,12629264,18978175,21375584,24413785,17329263,27358244,12011155,19359437,16764792,18755660,19857283,16998246,20950468,23207607,11151920,16791840,28320629,18279436,26958679,27064572,18467194,16126774,25010710,17238043,12452372,18938753,19959969,21499205,20814206,31088717,12078388,32553420,11880696,22526274,15552898,12815607,15084977,11544554,17072959,33909107,12120234,27409067,21525753,17539902,28456595,20562583,29515728,16552344,21792085,20059346,10406292,12227654,26372434,18946221,33097431,25792561,11115825,25058887,25546417,16327287,17448246,26110235,18414673,17641557,21844754,17079941,32387800,16128988,17641559,18184119,28546062,36599151,22572128,12560856,17466744,24236450,16623087,20416310,26089335,16915933,16508289,19696993,29206667,15463917,30134356,14576497,17943404,21734390,19433603,14576495,12324754,16427928,15948196,15782101,26784911,30241646,15097853,17072318,16632092,22608493,31900721,15753612,17314234,12649567,19383231,25492507,12631449,11950815,15513391,22363992,14628907,28861620,22369017,19885835,16632094,12408512,28176071,16733393,23090249,26376395,28536777,12705799,12068276,15238770,25569187,22629706,14752225,15758663,24713676,33972190,22343981,23745036,15584592,28454201,12765848,16699518,35408828,24260417,32439152,11578065,27603351,31860051,11276378,18063422,16258369,22781910,22306946,28502372,23143602,35974416,25400986,31940241,27000817,34828289,18680227,10529791,23721890,15528019,29318362,15645646,35212296,21610753,23503650,36057185,20001681,18604651,15128492,15802096,11175304,17525091,34798985,23741238,18652532,23455445,20722470,28440306,18350634,17477373,36264955,24458023,16358943,16849362,15479696,16912456,20452997,16301844,33720628,15047968,16303695,17050329,19713861,28780053,15618592,22885947,36517351,14718107,18462597,36369231,32240833,30992994,23622139,24326373,18182741,16958673,16254194,14968579,32352720,17175965,17274009,15121783,19299380,20116881,12483248,11824793,34140232,15148444,20837875,33202925,24052272,29859674,20601824,23554779,20980338,25556020,20980343,33257277,20834016,17415518,18986305,23474566,12467009,26884424,32624419,19140225,34996825,26820620,21257991,23847797,32658084,36191639,17090903,23160301,19890664,17873461,17297697,28556356,33375361,30755276,20460947,33963039,15265195,20208316,30789418,22749696,27432637,34923708,26166474,26719302,31506327,35288441,35096544,17238031,20484962,24653987,22955423,25981115,28095786,28650851,17033331,20814203,26273772,25838820,29154238,27748719,24624459,27264265,17381491,31310009,26038974,22088471,15980659,18442214,19096130,19369834,15901841,35577534,28609377,32742109,29657614,24954874,20335779,23686146,25667658,36655002,23955596,28611558,23230421,28348582,32989020,33565216,28648269,16216955,12825555,21504108[uid]

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Contribution of the CFTR gene, the pancreatic secretory trypsin inhibitor gene (SPINK1) and the cationic trypsinogen gene (PRSS1) to the etiology of recurrent pancreatitis.

Tzetis M, Kaliakatsos M, Fotoulaki M, Papatheodorou A, Doudounakis S, Tsezou A, Makrythanasis P, Kanavakis E, Nousia-Arvanitakis S. Tzetis M, et al. Clin Genet. 2007 May;71(5):451-7. doi: 10.1111/j.1399-0004.2007.00788.x. Clin Genet. 2007. PMID: 17489851

Analysis of CFTR, SPINK1, PRSS1 and AAT mutations in children with acute or chronic pancreatitis.

Sobczyńska-Tomaszewska A, Bak D, Oralewska B, Oracz G, Norek A, Czerska K, Mazurczak T, Teisseyre M, Socha J, Zagulski M, Bal J. Sobczyńska-Tomaszewska A, et al. J Pediatr Gastroenterol Nutr. 2006 Sep;43(3):299-306. doi: 10.1097/01.mpg.0000232570.48773.df. J Pediatr Gastroenterol Nutr. 2006. PMID: 16954950

CFTR, PRSS1 and SPINK1 mutations in the development of pancreatitis in Brazilian patients.

Bernardino AL, Guarita DR, Mott CB, Pedroso MR, Machado MC, Laudanna AA, Tani CM, Almeida FL, Zatz M. Bernardino AL, et al. JOP. 2003 Sep;4(5):169-77. JOP. 2003. PMID: 14526128

Identification of CFTR, PRSS1, and SPINK1 mutations in 381 patients with pancreatitis.

Keiles S, Kammesheidt A. Keiles S, et al. Pancreas. 2006 Oct;33(3):221-7. doi: 10.1097/01.mpa.0000232014.94974.75. Pancreas. 2006. PMID: 17003641

Pancreatitis risk in primary hyperparathyroidism: relation to mutations in the SPINK1 trypsin inhibitor (N34S) and the cystic fibrosis gene.

Felderbauer P, Karakas E, Fendrich V, Bulut K, Horn T, Lebert R, Holland-Letz T, Schmitz F, Bartsch D, Schmidt WE. Felderbauer P, et al. Am J Gastroenterol. 2008 Feb;103(2):368-74. doi: 10.1111/j.1572-0241.2007.01695.x. Epub 2007 Dec 12. Am J Gastroenterol. 2008. PMID: 18076731

Complete cystic fibrosis transmembrane conductance regulator gene sequencing in patients with idiopathic chronic pancreatitis and controls.

Weiss FU, Simon P, Bogdanova N, Mayerle J, Dworniczak B, Horst J, Lerch MM. Weiss FU, et al. Gut. 2005 Oct;54(10):1456-60. doi: 10.1136/gut.2005.064808. Epub 2005 Jun 29. Gut. 2005. PMID: 15987793 Free PMC article.

Mutation analysis of the cystic fibrosis transmembrane conductance regulator (CFTR) gene, the cationic trypsinogen (PRSS1) gene, and the serine protease inhibitor, Kazal type 1 (SPINK1) gene in patients with alcoholic chronic pancreatitis.

Perri F, Piepoli A, Stanziale P, Merla A, Zelante L, Andriulli A. Perri F, et al. Eur J Hum Genet. 2003 Sep;11(9):687-92. doi: 10.1038/sj.ejhg.5201035. Eur J Hum Genet. 2003. PMID: 12939655

Determination of the relative contribution of three genes-the cystic fibrosis transmembrane conductance regulator gene, the cationic trypsinogen gene, and the pancreatic secretory trypsin inhibitor gene-to the etiology of idiopathic chronic pancreatitis.

Audrézet MP, Chen JM, Le Maréchal C, Ruszniewski P, Robaszkiewicz M, Raguénès O, Quéré I, Scotet V, Férec C. Audrézet MP, et al. Eur J Hum Genet. 2002 Feb;10(2):100-6. doi: 10.1038/sj.ejhg.5200786. Eur J Hum Genet. 2002. PMID: 11938439

Genetic prevalence and characteristics in children with recurrent pancreatitis.

Sultan M, Werlin S, Venkatasubramani N. Sultan M, et al. J Pediatr Gastroenterol Nutr. 2012 May;54(5):645-50. doi: 10.1097/MPG.0b013e31823f0269. J Pediatr Gastroenterol Nutr. 2012. PMID: 22094894

Mutations in the SPINK1 gene in idiopathic pancreatitis Italian patients.

Gomez-Lira M, Bonamini D, Castellani C, Unis L, Cavallini G, Assael BM, Pignatti PF. Gomez-Lira M, et al. Eur J Hum Genet. 2003 Jul;11(7):543-6. doi: 10.1038/sj.ejhg.5200989. Eur J Hum Genet. 2003. PMID: 12825076

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