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Items: 1 to 20 of 293


The graded response to Sonic Hedgehog depends on cilia architecture.

Caspary T, Larkins CE, Anderson KV.

Dev Cell. 2007 May;12(5):767-78.


Disrupted dorsal neural tube BMP signaling in the cilia mutant Arl13b hnn stems from abnormal Shh signaling.

Horner VL, Caspary T.

Dev Biol. 2011 Jul 1;355(1):43-54. doi: 10.1016/j.ydbio.2011.04.019. Epub 2011 Apr 22.


Defective ciliogenesis, embryonic lethality and severe impairment of the Sonic Hedgehog pathway caused by inactivation of the mouse complex A intraflagellar transport gene Ift122/Wdr10, partially overlapping with the DNA repair gene Med1/Mbd4.

Cortellino S, Wang C, Wang B, Bassi MR, Caretti E, Champeval D, Calmont A, Jarnik M, Burch J, Zaret KS, Larue L, Bellacosa A.

Dev Biol. 2009 Jan 1;325(1):225-37. doi: 10.1016/j.ydbio.2008.10.020. Epub 2008 Oct 29.


The emergent design of the neural tube: prepattern, SHH morphogen and GLI code.

Ruiz i Altaba A, Nguyên V, Palma V.

Curr Opin Genet Dev. 2003 Oct;13(5):513-21. Review.


Mouse Rab23 regulates hedgehog signaling from smoothened to Gli proteins.

Eggenschwiler JT, Bulgakov OV, Qin J, Li T, Anderson KV.

Dev Biol. 2006 Feb 1;290(1):1-12. Epub 2005 Dec 20.


Primary cilia regulate hippocampal neurogenesis by mediating sonic hedgehog signaling.

Breunig JJ, Sarkisian MR, Arellano JI, Morozov YM, Ayoub AE, Sojitra S, Wang B, Flavell RA, Rakic P, Town T.

Proc Natl Acad Sci U S A. 2008 Sep 2;105(35):13127-32. doi: 10.1073/pnas.0804558105. Epub 2008 Aug 26.


Tulp3 is a critical repressor of mouse hedgehog signaling.

Cameron DA, Pennimpede T, Petkovich M.

Dev Dyn. 2009 May;238(5):1140-9. doi: 10.1002/dvdy.21926.


Arl13b regulates ciliogenesis and the dynamic localization of Shh signaling proteins.

Larkins CE, Aviles GD, East MP, Kahn RA, Caspary T.

Mol Biol Cell. 2011 Dec;22(23):4694-703. doi: 10.1091/mbc.E10-12-0994. Epub 2011 Oct 5.


Ftm is a novel basal body protein of cilia involved in Shh signalling.

Vierkotten J, Dildrop R, Peters T, Wang B, Rüther U.

Development. 2007 Jul;134(14):2569-77. Epub 2007 Jun 6.


Loss of the retrograde motor for IFT disrupts localization of Smo to cilia and prevents the expression of both activator and repressor functions of Gli.

May SR, Ashique AM, Karlen M, Wang B, Shen Y, Zarbalis K, Reiter J, Ericson J, Peterson AS.

Dev Biol. 2005 Nov 15;287(2):378-89. Epub 2005 Oct 17.


Rab23: what exactly does it traffic?

Wang Y, Ng EL, Tang BL.

Traffic. 2006 Jun;7(6):746-50. Review.


Patched1 regulates hedgehog signaling at the primary cilium.

Rohatgi R, Milenkovic L, Scott MP.

Science. 2007 Jul 20;317(5836):372-6.


Hedgehog signaling and primary cilia are required for the formation of adult neural stem cells.

Han YG, Spassky N, Romaguera-Ros M, Garcia-Verdugo JM, Aguilar A, Schneider-Maunoury S, Alvarez-Buylla A.

Nat Neurosci. 2008 Mar;11(3):277-84. doi: 10.1038/nn2059. Epub 2008 Feb 24.


Intraflagellar transport protein 122 antagonizes Sonic Hedgehog signaling and controls ciliary localization of pathway components.

Qin J, Lin Y, Norman RX, Ko HW, Eggenschwiler JT.

Proc Natl Acad Sci U S A. 2011 Jan 25;108(4):1456-61. doi: 10.1073/pnas.1011410108. Epub 2011 Jan 5.


FKBP8 is a negative regulator of mouse sonic hedgehog signaling in neural tissues.

Bulgakov OV, Eggenschwiler JT, Hong DH, Anderson KV, Li T.

Development. 2004 May;131(9):2149-59.


The ciliary G-protein-coupled receptor Gpr161 negatively regulates the Sonic hedgehog pathway via cAMP signaling.

Mukhopadhyay S, Wen X, Ratti N, Loktev A, Rangell L, Scales SJ, Jackson PK.

Cell. 2013 Jan 17;152(1-2):210-23. doi: 10.1016/j.cell.2012.12.026.


Sonic hedgehog induces transcription-independent cytoskeletal rearrangement and migration regulated by arachidonate metabolites.

Bijlsma MF, Borensztajn KS, Roelink H, Peppelenbosch MP, Spek CA.

Cell Signal. 2007 Dec;19(12):2596-604. Epub 2007 Aug 24.


G-protein-coupled receptors and localized signaling in the primary cilium during ventral neural tube patterning.

Hwang SH, Mukhopadhyay S.

Birth Defects Res A Clin Mol Teratol. 2015 Jan;103(1):12-9. doi: 10.1002/bdra.23267. Epub 2014 Jun 11.

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