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Results: 1 to 20 of 112

1.

Toll-like receptor 9-dependent activation by DNA-containing immune complexes is mediated by HMGB1 and RAGE.

Tian J, Avalos AM, Mao SY, Chen B, Senthil K, Wu H, Parroche P, Drabic S, Golenbock D, Sirois C, Hua J, An LL, Audoly L, La Rosa G, Bierhaus A, Naworth P, Marshak-Rothstein A, Crow MK, Fitzgerald KA, Latz E, Kiener PA, Coyle AJ.

Nat Immunol. 2007 May;8(5):487-96. Epub 2007 Apr 8. Erratum in: Nat Immunol. 2007 Jul;8(7):780.

PMID:
17417641
[PubMed - indexed for MEDLINE]
2.

RAGE-independent autoreactive B cell activation in response to chromatin and HMGB1/DNA immune complexes.

Avalos AM, Kiefer K, Tian J, Christensen S, Shlomchik M, Coyle AJ, Marshak-Rothstein A.

Autoimmunity. 2010 Feb;43(1):103-10. doi: 10.3109/08916930903384591.

PMID:
20014975
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Requirement of HMGB1 and RAGE for the maturation of human plasmacytoid dendritic cells.

Dumitriu IE, Baruah P, Bianchi ME, Manfredi AA, Rovere-Querini P.

Eur J Immunol. 2005 Jul;35(7):2184-90.

PMID:
15915542
[PubMed - indexed for MEDLINE]
4.

High-mobility group box 1 represents a potential marker of disease activity and novel therapeutic target in systemic lupus erythematosus.

Urbonaviciute V, Voll RE.

J Intern Med. 2011 Oct;270(4):309-18. doi: 10.1111/j.1365-2796.2011.02432.x.

PMID:
21793951
[PubMed - indexed for MEDLINE]
5.

Higher-order CpG-DNA stimulation reveals distinct activation requirements for marginal zone and follicular B cells in lupus mice.

Brummel R, Roberts TL, Stacey KJ, Lenert P.

Eur J Immunol. 2006 Jul;36(7):1951-62.

PMID:
16791898
[PubMed - indexed for MEDLINE]
6.

Mitochondrial transcription factor A, an endogenous danger signal, promotes TNF╬▒ release via RAGE- and TLR9-responsive plasmacytoid dendritic cells.

Julian MW, Shao G, Vangundy ZC, Papenfuss TL, Crouser ED.

PLoS One. 2013 Aug 12;8(8):e72354. doi: 10.1371/journal.pone.0072354. eCollection 2013.

PMID:
23951313
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Requirement for DNA CpG content in TLR9-dependent dendritic cell activation induced by DNA-containing immune complexes.

Yasuda K, Richez C, Uccellini MB, Richards RJ, Bonegio RG, Akira S, Monestier M, Corley RB, Viglianti GA, Marshak-Rothstein A, Rifkin IR.

J Immunol. 2009 Sep 1;183(5):3109-17. doi: 10.4049/jimmunol.0900399. Epub 2009 Jul 31.

PMID:
19648272
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

TLR-9 activation of marginal zone B cells in lupus mice regulates immunity through increased IL-10 production.

Lenert P, Brummel R, Field EH, Ashman RF.

J Clin Immunol. 2005 Jan;25(1):29-40.

PMID:
15742155
[PubMed - indexed for MEDLINE]
9.

DNA-like class R inhibitory oligonucleotides (INH-ODNs) preferentially block autoantigen-induced B-cell and dendritic cell activation in vitro and autoantibody production in lupus-prone MRL-Fas(lpr/lpr) mice in vivo.

Lenert P, Yasuda K, Busconi L, Nelson P, Fleenor C, Ratnabalasuriar RS, Nagy PL, Ashman RF, Rifkin IR, Marshak-Rothstein A.

Arthritis Res Ther. 2009;11(3):R79. doi: 10.1186/ar2710. Epub 2009 May 28.

PMID:
19476613
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Vaccination with plasmid DNA activates dendritic cells via Toll-like receptor 9 (TLR9) but functions in TLR9-deficient mice.

Spies B, Hochrein H, Vabulas M, Huster K, Busch DH, Schmitz F, Heit A, Wagner H.

J Immunol. 2003 Dec 1;171(11):5908-12.

PMID:
14634101
[PubMed - indexed for MEDLINE]
Free Article
12.

Human lupus autoantibody-DNA complexes activate DCs through cooperation of CD32 and TLR9.

Means TK, Latz E, Hayashi F, Murali MR, Golenbock DT, Luster AD.

J Clin Invest. 2005 Feb;115(2):407-17.

PMID:
15668740
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Toll-like receptor 9-dependent immune activation by unmethylated CpG motifs in Aspergillus fumigatus DNA.

Ramirez-Ortiz ZG, Specht CA, Wang JP, Lee CK, Bartholomeu DC, Gazzinelli RT, Levitz SM.

Infect Immun. 2008 May;76(5):2123-9. doi: 10.1128/IAI.00047-08. Epub 2008 Mar 10.

PMID:
18332208
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

RAGE is the major receptor for the proinflammatory activity of HMGB1 in rodent macrophages.

Kokkola R, Andersson A, Mullins G, Ostberg T, Treutiger CJ, Arnold B, Nawroth P, Andersson U, Harris RA, Harris HE.

Scand J Immunol. 2005 Jan;61(1):1-9.

PMID:
15644117
[PubMed - indexed for MEDLINE]
15.

Differential signaling by CpG DNA in DCs and B cells: not just TLR9.

Verthelyi D, Zeuner RA.

Trends Immunol. 2003 Oct;24(10):519-22. Review.

PMID:
14552833
[PubMed - indexed for MEDLINE]
16.

Immunomodulatory oligonucleotides containing a cytosine-phosphate-2'-deoxy-7-deazaguanosine motif as potent toll-like receptor 9 agonists.

Kandimalla ER, Bhagat L, Li Y, Yu D, Wang D, Cong YP, Song SS, Tang JX, Sullivan T, Agrawal S.

Proc Natl Acad Sci U S A. 2005 May 10;102(19):6925-30. Epub 2005 Apr 28.

PMID:
15860583
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

B-cell receptor for antigen modulates B-cell responses to complex TLR9 agonists and antagonists: implications for systemic lupus erythematosus.

Goeken JA, Layer T, Fleenor S, Laccheo M, Lenert P.

Lupus. 2010 Oct;19(11):1290-301. doi: 10.1177/0961203310371157. Epub 2010 Jul 6.

PMID:
20605877
[PubMed - indexed for MEDLINE]
18.

TLR9 activation is defective in common variable immune deficiency.

Cunningham-Rundles C, Radigan L, Knight AK, Zhang L, Bauer L, Nakazawa A.

J Immunol. 2006 Feb 1;176(3):1978-87.

PMID:
16424230
[PubMed - indexed for MEDLINE]
Free Article
19.

TLR9/TLR7-triggered downregulation of BDCA2 expression on human plasmacytoid dendritic cells from healthy individuals and lupus patients.

Wu P, Wu J, Liu S, Han X, Lu J, Shi Y, Wang J, Lu L, Cao X.

Clin Immunol. 2008 Oct;129(1):40-8. doi: 10.1016/j.clim.2008.06.004. Epub 2008 Aug 5.

PMID:
18684674
[PubMed - indexed for MEDLINE]
20.

High mobility group B1 protein suppresses the human plasmacytoid dendritic cell response to TLR9 agonists.

Popovic PJ, DeMarco R, Lotze MT, Winikoff SE, Bartlett DL, Krieg AM, Guo ZS, Brown CK, Tracey KJ, Zeh HJ 3rd.

J Immunol. 2006 Dec 15;177(12):8701-7.

PMID:
17142771
[PubMed - indexed for MEDLINE]
Free Article

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