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Results: 1 to 20 of 216

1.

TRF2 overexpression diminishes repair of telomeric single-strand breaks and accelerates telomere shortening in human fibroblasts.

Richter T, Saretzki G, Nelson G, Melcher M, Olijslagers S, von Zglinicki T.

Mech Ageing Dev. 2007 Apr;128(4):340-5. Epub 2007 Mar 4.

PMID:
17395247
[PubMed - indexed for MEDLINE]
2.

A RAP1/TRF2 complex inhibits nonhomologous end-joining at human telomeric DNA ends.

Bae NS, Baumann P.

Mol Cell. 2007 May 11;26(3):323-34.

PMID:
17499040
[PubMed - indexed for MEDLINE]
Free Article
3.

XPF with mutations in its conserved nuclease domain is defective in DNA repair but functions in TRF2-mediated telomere shortening.

Wu Y, Zacal NJ, Rainbow AJ, Zhu XD.

DNA Repair (Amst). 2007 Feb 4;6(2):157-66. Epub 2006 Oct 18.

PMID:
17055345
[PubMed - indexed for MEDLINE]
4.

TRF2 is required for repair of nontelomeric DNA double-strand breaks by homologous recombination.

Mao Z, Seluanov A, Jiang Y, Gorbunova V.

Proc Natl Acad Sci U S A. 2007 Aug 7;104(32):13068-73. Epub 2007 Aug 1.

PMID:
17670947
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Accumulation of single-strand breaks is the major cause of telomere shortening in human fibroblasts.

von Zglinicki T, Pilger R, Sitte N.

Free Radic Biol Med. 2000 Jan 1;28(1):64-74.

PMID:
10656292
[PubMed - indexed for MEDLINE]
6.

Telomere damage induced by the G-quadruplex ligand RHPS4 has an antitumor effect.

Salvati E, Leonetti C, Rizzo A, Scarsella M, Mottolese M, Galati R, Sperduti I, Stevens MF, D'Incalci M, Blasco M, Chiorino G, Bauwens S, Horard B, Gilson E, Stoppacciaro A, Zupi G, Biroccio A.

J Clin Invest. 2007 Nov;117(11):3236-47.

PMID:
17932567
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Control of human telomere length by TRF1 and TRF2.

Smogorzewska A, van Steensel B, Bianchi A, Oelmann S, Schaefer MR, Schnapp G, de Lange T.

Mol Cell Biol. 2000 Mar;20(5):1659-68.

PMID:
10669743
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

WRN controls formation of extrachromosomal telomeric circles and is required for TRF2DeltaB-mediated telomere shortening.

Li B, Jog SP, Reddy S, Comai L.

Mol Cell Biol. 2008 Mar;28(6):1892-904. doi: 10.1128/MCB.01364-07. Epub 2008 Jan 22.

PMID:
18212065
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Telomere protection: an act of God.

Szilard RK, Durocher D.

Curr Biol. 2006 Jul 25;16(14):R544-6.

PMID:
16860732
[PubMed - indexed for MEDLINE]
Free Article
10.

hSnm1B is a novel telomere-associated protein.

Freibaum BD, Counter CM.

J Biol Chem. 2006 Jun 2;281(22):15033-6. Epub 2006 Apr 10.

PMID:
16606622
[PubMed - indexed for MEDLINE]
Free Article
11.

Oxidative damage in telomeric DNA disrupts recognition by TRF1 and TRF2.

Opresko PL, Fan J, Danzy S, Wilson DM 3rd, Bohr VA.

Nucleic Acids Res. 2005 Feb 24;33(4):1230-9. Print 2005.

PMID:
15731343
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Tethering telomeric double- and single-stranded DNA-binding proteins inhibits telomere elongation.

Etheridge KT, Compton SA, Barrientos KS, Ozgur S, Griffith JD, Counter CM.

J Biol Chem. 2008 Mar 14;283(11):6935-41. doi: 10.1074/jbc.M708711200. Epub 2008 Jan 3.

PMID:
18178559
[PubMed - indexed for MEDLINE]
Free Article
13.

The telomeric protein TRF2 is critical for the protection of A549 cells from both telomere erosion and DNA double-strand breaks driven by salvicine.

Zhang YW, Zhang ZX, Miao ZH, Ding J.

Mol Pharmacol. 2008 Mar;73(3):824-32. Epub 2007 Nov 19. Erratum in: Mol Pharmacol. 2008 May;73(5):1587.

PMID:
18025071
[PubMed - indexed for MEDLINE]
Free Article
14.

G-Quadruplex stabilization by telomestatin induces TRF2 protein dissociation from telomeres and anaphase bridge formation accompanied by loss of the 3' telomeric overhang in cancer cells.

Tahara H, Shin-Ya K, Seimiya H, Yamada H, Tsuruo T, Ide T.

Oncogene. 2006 Mar 23;25(13):1955-66.

PMID:
16302000
[PubMed - indexed for MEDLINE]
15.

Telomere length homeostasis requires that telomerase levels are limiting.

Cristofari G, Lingner J.

EMBO J. 2006 Feb 8;25(3):565-74. Epub 2006 Jan 19.

PMID:
16424902
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

A mathematical model of cellular apoptosis and senescence through the dynamics of telomere loss.

Arkus N.

J Theor Biol. 2005 Jul 7;235(1):13-32.

PMID:
15833310
[PubMed - indexed for MEDLINE]
17.

The Apollo 5' exonuclease functions together with TRF2 to protect telomeres from DNA repair.

Lenain C, Bauwens S, Amiard S, Brunori M, Giraud-Panis MJ, Gilson E.

Curr Biol. 2006 Jul 11;16(13):1303-10. Epub 2006 May 25.

PMID:
16730175
[PubMed - indexed for MEDLINE]
Free Article
18.

Mammalian Ku86 protein prevents telomeric fusions independently of the length of TTAGGG repeats and the G-strand overhang.

Samper E, Goytisolo FA, Slijepcevic P, van Buul PP, Blasco MA.

EMBO Rep. 2000 Sep;1(3):244-52.

PMID:
11256607
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Oxidative stress--induced single-strand breaks in chromosomal telomeres of human retinal pigment epithelial cells in vitro.

Honda S, Hjelmeland LM, Handa JT.

Invest Ophthalmol Vis Sci. 2001 Aug;42(9):2139-44.

PMID:
11481283
[PubMed - indexed for MEDLINE]
Free Article
20.

DNA structure-dependent recruitment of telomeric proteins to single-stranded/double-stranded DNA junctions.

Yanez GH, Khan SJ, Locovei AM, Pedroso IM, Fletcher TM.

Biochem Biophys Res Commun. 2005 Mar 4;328(1):49-56.

PMID:
15670749
[PubMed - indexed for MEDLINE]

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