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Epigenetic signatures of stem-cell identity.

Spivakov M, Fisher AG.

Nat Rev Genet. 2007 Apr;8(4):263-71. Review.


Dynamic chromatin states in human ES cells reveal potential regulatory sequences and genes involved in pluripotency.

Hawkins RD, Hon GC, Yang C, Antosiewicz-Bourget JE, Lee LK, Ngo QM, Klugman S, Ching KA, Edsall LE, Ye Z, Kuan S, Yu P, Liu H, Zhang X, Green RD, Lobanenkov VV, Stewart R, Thomson JA, Ren B.

Cell Res. 2011 Oct;21(10):1393-409. doi: 10.1038/cr.2011.146. Epub 2011 Aug 30.


Epigenetic control of embryonic stem cell fate.

Christophersen NS, Helin K.

J Exp Med. 2010 Oct 25;207(11):2287-95. doi: 10.1084/jem.20101438. Review.


Oct4 interaction with Hmgb2 regulates Akt signaling and pluripotency.

Campbell PA, Rudnicki MA.

Stem Cells. 2013 Jun;31(6):1107-20. doi: 10.1002/stem.1365.


Epigenetics in embryonic stem cells: regulation of pluripotency and differentiation.

Atkinson S, Armstrong L.

Cell Tissue Res. 2008 Jan;331(1):23-9. Epub 2007 Nov 15. Review.


Stat3 and c-Myc genome-wide promoter occupancy in embryonic stem cells.

Kidder BL, Yang J, Palmer S.

PLoS One. 2008;3(12):e3932. doi: 10.1371/journal.pone.0003932. Epub 2008 Dec 11.


Genomewide analysis of PRC1 and PRC2 occupancy identifies two classes of bivalent domains.

Ku M, Koche RP, Rheinbay E, Mendenhall EM, Endoh M, Mikkelsen TS, Presser A, Nusbaum C, Xie X, Chi AS, Adli M, Kasif S, Ptaszek LM, Cowan CA, Lander ES, Koseki H, Bernstein BE.

PLoS Genet. 2008 Oct;4(10):e1000242. doi: 10.1371/journal.pgen.1000242. Epub 2008 Oct 31.


Chromatin signatures of pluripotent cell lines.

Azuara V, Perry P, Sauer S, Spivakov M, Jørgensen HF, John RM, Gouti M, Casanova M, Warnes G, Merkenschlager M, Fisher AG.

Nat Cell Biol. 2006 May;8(5):532-8. Epub 2006 Mar 29.


Factor mediated gene priming in pluripotent stem cells sets the stage for lineage specification.

Dillon N.

Bioessays. 2012 Mar;34(3):194-204. doi: 10.1002/bies.201100137. Epub 2012 Jan 13. Review.


TIF1beta regulates the pluripotency of embryonic stem cells in a phosphorylation-dependent manner.

Seki Y, Kurisaki A, Watanabe-Susaki K, Nakajima Y, Nakanishi M, Arai Y, Shiota K, Sugino H, Asashima M.

Proc Natl Acad Sci U S A. 2010 Jun 15;107(24):10926-31. doi: 10.1073/pnas.0907601107. Epub 2010 May 27. Erratum in: Proc Natl Acad Sci U S A. 2010 Jul 27;107(30):13556.


Histone variant macroH2A marks embryonic differentiation in vivo and acts as an epigenetic barrier to induced pluripotency.

Pasque V, Radzisheuskaya A, Gillich A, Halley-Stott RP, Panamarova M, Zernicka-Goetz M, Surani MA, Silva JC.

J Cell Sci. 2012 Dec 15;125(Pt 24):6094-104. doi: 10.1242/jcs.113019. Epub 2012 Oct 17.


Embryonic stem cell potency fluctuates with endogenous retrovirus activity.

Macfarlan TS, Gifford WD, Driscoll S, Lettieri K, Rowe HM, Bonanomi D, Firth A, Singer O, Trono D, Pfaff SL.

Nature. 2012 Jul 5;487(7405):57-63. doi: 10.1038/nature11244.


Polycomb repressive complex 2 in embryonic stem cells: an overview.

Jones A, Wang H.

Protein Cell. 2010 Dec;1(12):1056-62. doi: 10.1007/s13238-010-0142-7. Epub 2011 Jan 8. Review.


Epigenetic patterns of embryonic and adult stem cells.

Bloushtain-Qimron N, Yao J, Shipitsin M, Maruyama R, Polyak K.

Cell Cycle. 2009 Mar 15;8(6):809-17. Epub 2009 Mar 26.


REST maintains self-renewal and pluripotency of embryonic stem cells.

Singh SK, Kagalwala MN, Parker-Thornburg J, Adams H, Majumder S.

Nature. 2008 May 8;453(7192):223-7. doi: 10.1038/nature06863. Epub 2008 Mar 23.


Jmjd1a and Jmjd2c histone H3 Lys 9 demethylases regulate self-renewal in embryonic stem cells.

Loh YH, Zhang W, Chen X, George J, Ng HH.

Genes Dev. 2007 Oct 15;21(20):2545-57.


Nonoverlapping functions of the Polycomb group Cbx family of proteins in embryonic stem cells.

Morey L, Pascual G, Cozzuto L, Roma G, Wutz A, Benitah SA, Di Croce L.

Cell Stem Cell. 2012 Jan 6;10(1):47-62. doi: 10.1016/j.stem.2011.12.006.


Polycomb complexes repress developmental regulators in murine embryonic stem cells.

Boyer LA, Plath K, Zeitlinger J, Brambrink T, Medeiros LA, Lee TI, Levine SS, Wernig M, Tajonar A, Ray MK, Bell GW, Otte AP, Vidal M, Gifford DK, Young RA, Jaenisch R.

Nature. 2006 May 18;441(7091):349-53. Epub 2006 Apr 19.


Unrestricted somatic stem cells (USSC) from human umbilical cord blood display uncommitted epigenetic signatures of the major stem cell pluripotency genes.

Santourlidis S, Wernet P, Ghanjati F, Graffmann N, Springer J, Kriegs C, Zhao X, Brands J, Araúzo-Bravo MJ, Neves R, Koegler G, Uhrberg M.

Stem Cell Res. 2011 Jan;6(1):60-9. doi: 10.1016/j.scr.2010.08.003. Epub 2010 Aug 27.


Intracellular α-ketoglutarate maintains the pluripotency of embryonic stem cells.

Carey BW, Finley LW, Cross JR, Allis CD, Thompson CB.

Nature. 2015 Feb 19;518(7539):413-6. doi: 10.1038/nature13981. Epub 2014 Dec 10.

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