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Results: 1 to 20 of 127

1.

Mutagenicity of zidovudine, lamivudine, and abacavir following in vitro exposure of human lymphoblastoid cells or in utero exposure of CD-1 mice to single agents or drug combinations.

Torres SM, Walker DM, Carter MM, Cook DL Jr, McCash CL, Cordova EM, Olivero OA, Poirier MC, Walker VE.

Environ Mol Mutagen. 2007 Apr-May;48(3-4):224-38.

PMID:
17358033
[PubMed - indexed for MEDLINE]
2.

Relative mutagenic potencies of several nucleoside analogs, alone or in drug pairs, at the HPRT and TK loci of human TK6 lymphoblastoid cells.

Carter MM, Torres SM, Cook DL Jr, McCash CL, Yu M, Walker VE, Walker DM.

Environ Mol Mutagen. 2007 Apr-May;48(3-4):239-47.

PMID:
17358029
[PubMed - indexed for MEDLINE]
3.

Transplacental drug transfer and frequency of Tk and Hprt lymphocyte mutants and peripheral blood micronuclei in mice treated transplacentally with zidovudine and lamivudine.

Von Tungeln LS, Williams LD, Doerge DR, Shaddock JG, McGarrity LJ, Morris SM, Mittelstaedt RA, Heflich RH, Beland FA.

Environ Mol Mutagen. 2007 Apr-May;48(3-4):258-69.

PMID:
16850453
[PubMed - indexed for MEDLINE]
4.

Frequency of Tk and Hprt lymphocyte mutants and bone marrow micronuclei in B6C3F(1)/Tk+/- mice treated neonatally with zidovudine and lamivudine.

Von Tungeln LS, Hamilton LP, Dobrovolsky VN, Bishop ME, Shaddock JG, Heflich RH, Beland FA.

Carcinogenesis. 2002 Sep;23(9):1427-32.

PMID:
12189183
[PubMed - indexed for MEDLINE]
Free Article
5.

Frequency of Hprt mutant lymphocytes and micronucleated erythrocytes in p53-haplodeficient mice treated perinatally with AZT and AZT in combination with 3TC.

Dobrovolsky VN, Shaddock JG, Mittelstaedt RA, Bishop ME, Lewis SM, Lee FW, Aidoo A, Leakey JE, Dunnick JK, Heflich RH.

Environ Mol Mutagen. 2007 Apr-May;48(3-4):270-82.

PMID:
17358030
[PubMed - indexed for MEDLINE]
6.

Mitochondrial toxicity in hearts of CD-1 mice following perinatal exposure to AZT, 3TC, or AZT/3TC in combination.

Chan SS, Santos JH, Meyer JN, Mandavilli BS, Cook DL Jr, McCash CL, Kissling GE, Nyska A, Foley JF, van Houten B, Copeland WC, Walker VE, Witt KL, Bishop JB.

Environ Mol Mutagen. 2007 Apr-May;48(3-4):190-200.

PMID:
16395692
[PubMed - indexed for MEDLINE]
7.

Frequency of Tk and Hprt lymphocyte mutants and bone marrow micronuclei in mice treated neonatally with zidovudine and didanosine.

Von Tungeln LS, Dobrovolsky VN, Bishop ME, Shaddock JG, Heflich RH, Beland FA.

Mutagenesis. 2004 Jul;19(4):307-11.

PMID:
15215330
[PubMed - indexed for MEDLINE]
Free Article
8.

Genotoxicity assessed by the comet and GPA assays following in vitro exposure of human lymphoblastoid cells (H9) or perinatal exposure of mother-child pairs to AZT or AZT-3TC.

Escobar PA, Olivero OA, Wade NA, Abrams EJ, Nesel CJ, Ness RB, Day RD, Day BW, Meng Q, O'Neill JP, Walker DM, Poirier MC, Walker VE, Bigbee WL.

Environ Mol Mutagen. 2007 Apr-May;48(3-4):330-43.

PMID:
17358027
[PubMed - indexed for MEDLINE]
9.
10.

In utero exposure of female CD-1 Mice to AZT and/or 3TC: I. Persistence of microscopic lesions in cardiac tissue.

Torres SM, March TH, Carter MM, McCash CL, Seilkop SK, Poirier MC, Walker DM, Walker VE.

Cardiovasc Toxicol. 2010 Mar;10(1):37-50. doi: 10.1007/s12012-010-9061-3.

PMID:
20101476
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Zidovudine induces S-phase arrest and cell cycle gene expression changes in human cells.

Olivero OA, Tejera AM, Fernandez JJ, Taylor BJ, Das S, Divi RL, Poirier MC.

Mutagenesis. 2005 Mar;20(2):139-46. Epub 2005 Mar 22.

PMID:
15784690
[PubMed - indexed for MEDLINE]
Free Article
12.

Genotoxicity of 3'-azido-3'-deoxythymidine in the human lymphoblastoid cell line, TK6: relationships between DNA incorporation, mutant frequency, and spectrum of deletion mutations in HPRT.

Sussman HE, Olivero OA, Meng Q, Pietras SM, Poirier MC, O'Neill JP, Finette BA, Bauer MJ, Walker VE.

Mutat Res. 1999 Oct 19;429(2):249-59.

PMID:
10526209
[PubMed - indexed for MEDLINE]
13.

Relationships between DNA incorporation, mutant frequency, and loss of heterozygosity at the TK locus in human lymphoblastoid cells exposed to 3'-azido-3'-deoxythymidine.

Meng Q, Su T, Olivero OA, Poirier MC, Shi X, Ding X, Walker VE.

Toxicol Sci. 2000 Apr;54(2):322-9.

PMID:
10774814
[PubMed - indexed for MEDLINE]
Free Article
14.

In utero exposure of female CD-1 mice to AZT and/or 3TC: II. Persistence of functional alterations in cardiac tissue.

Torres SM, Divi RL, Walker DM, McCash CL, Carter MM, Campen MJ, Einem TL, Chu Y, Seilkop SK, Kang H, Poirier MC, Walker VE.

Cardiovasc Toxicol. 2010 Jun;10(2):87-99. doi: 10.1007/s12012-010-9065-z.

PMID:
20155331
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Transplacental genotoxicity of combined antiretroviral nucleoside analogue therapy in Erythrocebus patas monkeys.

Olivero OA, Fernandez JJ, Antiochos BB, Wagner JL, St Claire ME, Poirier MC.

J Acquir Immune Defic Syndr. 2002 Apr 1;29(4):323-9. Erratum in: J Acquir Immune Defic Syndr 2002 Jul 1;30(3):368.

PMID:
11917235
[PubMed - indexed for MEDLINE]
17.

Zidovudine-didanosine coexposure potentiates DNA incorporation of zidovudine and mutagenesis in human cells.

Meng Q, Walker DM, Olivero OA, Shi X, Antiochos BB, Poirier MC, Walker VE.

Proc Natl Acad Sci U S A. 2000 Nov 7;97(23):12667-71.

PMID:
11058153
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Mitochondrial toxicity in fetal Erythrocebus patas monkeys exposed transplacentally to zidovudine plus lamivudine.

Gerschenson M, Nguyen V, Ewings EL, Ceresa A, Shaw JA, St Claire MC, Nagashima K, Harbaugh SW, Harbaugh JW, Olivero OA, Divi RL, Albert PS, Poirier MC.

AIDS Res Hum Retroviruses. 2004 Jan;20(1):91-100.

PMID:
15000702
[PubMed - indexed for MEDLINE]
19.

Genotoxicity of 1,3-butadiene and its epoxy intermediates.

Walker VE, Walker DM, Meng Q, McDonald JD, Scott BR, Seilkop SK, Claffey DJ, Upton PB, Powley MW, Swenberg JA, Henderson RF; Health Review Committee.

Res Rep Health Eff Inst. 2009 Aug;(144):3-79.

PMID:
20017413
[PubMed - indexed for MEDLINE]
20.

Prenatal AZT or 3TC and mouse development of locomotor activity and hot-plate responding upon administration of the GABA(A) receptor agonist muscimol.

Ricceri L, Venerosi A, Valanzano A, Sorace A, Alleva E.

Psychopharmacology (Berl). 2001 Feb;153(4):434-42.

PMID:
11243490
[PubMed - indexed for MEDLINE]

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