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Results: 1 to 20 of 104

1.

Genome-wide analysis of genetic alterations in acute lymphoblastic leukaemia.

Mullighan CG, Goorha S, Radtke I, Miller CB, Coustan-Smith E, Dalton JD, Girtman K, Mathew S, Ma J, Pounds SB, Su X, Pui CH, Relling MV, Evans WE, Shurtleff SA, Downing JR.

Nature. 2007 Apr 12;446(7137):758-64.

PMID:
17344859
[PubMed - indexed for MEDLINE]
2.

PAX5 mutations occur frequently in adult B-cell progenitor acute lymphoblastic leukemia and PAX5 haploinsufficiency is associated with BCR-ABL1 and TCF3-PBX1 fusion genes: a GRAALL study.

Familiades J, Bousquet M, Lafage-Pochitaloff M, Béné MC, Beldjord K, De Vos J, Dastugue N, Coyaud E, Struski S, Quelen C, Prade-Houdellier N, Dobbelstein S, Cayuela JM, Soulier J, Grardel N, Preudhomme C, Cavé H, Blanchet O, Lhéritier V, Delannoy A, Chalandon Y, Ifrah N, Pigneux A, Brousset P, Macintyre EA, Huguet F, Dombret H, Broccardo C, Delabesse E.

Leukemia. 2009 Nov;23(11):1989-98. doi: 10.1038/leu.2009.135. Epub 2009 Jul 9.

PMID:
19587702
[PubMed - indexed for MEDLINE]
3.

Oncogenic role of Pax5 in the T-lymphoid lineage upon ectopic expression from the immunoglobulin heavy-chain locus.

Souabni A, Jochum W, Busslinger M.

Blood. 2007 Jan 1;109(1):281-9. Epub 2006 Sep 12.

PMID:
16968900
[PubMed - indexed for MEDLINE]
Free Article
4.

Ebf1 or Pax5 haploinsufficiency synergizes with STAT5 activation to initiate acute lymphoblastic leukemia.

Heltemes-Harris LM, Willette MJ, Ramsey LB, Qiu YH, Neeley ES, Zhang N, Thomas DA, Koeuth T, Baechler EC, Kornblau SM, Farrar MA.

J Exp Med. 2011 Jun 6;208(6):1135-49. doi: 10.1084/jem.20101947. Epub 2011 May 23.

PMID:
21606506
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

The PAX5 gene is frequently rearranged in BCR-ABL1-positive acute lymphoblastic leukemia but is not associated with outcome. A report on behalf of the GIMEMA Acute Leukemia Working Party.

Iacobucci I, Lonetti A, Paoloni F, Papayannidis C, Ferrari A, Storlazzi CT, Vignetti M, Cilloni D, Messa F, Guadagnuolo V, Paolini S, Elia L, Messina M, Vitale A, Meloni G, Soverini S, Pane F, Baccarani M, Foà R, Martinelli G.

Haematologica. 2010 Oct;95(10):1683-90. doi: 10.3324/haematol.2009.020792. Epub 2010 Jun 9.

PMID:
20534699
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Genomic profiling of B-progenitor acute lymphoblastic leukemia.

Mullighan CG.

Best Pract Res Clin Haematol. 2011 Dec;24(4):489-503. doi: 10.1016/j.beha.2011.09.004. Epub 2011 Nov 6. Review.

PMID:
22127311
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Genomics: global views of leukaemia.

Golub TR.

Nature. 2007 Apr 12;446(7137):739-40. No abstract available.

PMID:
17429386
[PubMed - indexed for MEDLINE]
8.

Deletion of IKZF1 and prognosis in acute lymphoblastic leukemia.

Mullighan CG, Su X, Zhang J, Radtke I, Phillips LA, Miller CB, Ma J, Liu W, Cheng C, Schulman BA, Harvey RC, Chen IM, Clifford RJ, Carroll WL, Reaman G, Bowman WP, Devidas M, Gerhard DS, Yang W, Relling MV, Shurtleff SA, Campana D, Borowitz MJ, Pui CH, Smith M, Hunger SP, Willman CL, Downing JR; Children's Oncology Group.

N Engl J Med. 2009 Jan 29;360(5):470-80. doi: 10.1056/NEJMoa0808253. Epub 2009 Jan 7.

PMID:
19129520
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

BCR-ABL1 lymphoblastic leukaemia is characterized by the deletion of Ikaros.

Mullighan CG, Miller CB, Radtke I, Phillips LA, Dalton J, Ma J, White D, Hughes TP, Le Beau MM, Pui CH, Relling MV, Shurtleff SA, Downing JR.

Nature. 2008 May 1;453(7191):110-4. doi: 10.1038/nature06866. Epub 2008 Apr 13.

PMID:
18408710
[PubMed - indexed for MEDLINE]
10.

Variable breakpoints target PAX5 in patients with dicentric chromosomes: a model for the basis of unbalanced translocations in cancer.

An Q, Wright SL, Konn ZJ, Matheson E, Minto L, Moorman AV, Parker H, Griffiths M, Ross FM, Davies T, Hall AG, Harrison CJ, Irving JA, Strefford JC.

Proc Natl Acad Sci U S A. 2008 Nov 4;105(44):17050-4. doi: 10.1073/pnas.0803494105. Epub 2008 Oct 28.

PMID:
18957548
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

A subtype of childhood acute lymphoblastic leukaemia with poor treatment outcome: a genome-wide classification study.

Den Boer ML, van Slegtenhorst M, De Menezes RX, Cheok MH, Buijs-Gladdines JG, Peters ST, Van Zutven LJ, Beverloo HB, Van der Spek PJ, Escherich G, Horstmann MA, Janka-Schaub GE, Kamps WA, Evans WE, Pieters R.

Lancet Oncol. 2009 Feb;10(2):125-34. doi: 10.1016/S1470-2045(08)70339-5. Epub 2009 Jan 8.

PMID:
19138562
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

High-resolution genomic profiling of pediatric lymphoblastic lymphomas reveals subtle differences with pediatric acute lymphoblastic leukemias in the B-lineage.

Schraders M, van Reijmersdal SV, Kamping EJ, van Krieken JH, van Kessel AG, Groenen PJ, Hoogerbrugge PM, Kuiper RP.

Cancer Genet Cytogenet. 2009 May;191(1):27-33. doi: 10.1016/j.cancergencyto.2009.01.002.

PMID:
19389505
[PubMed - indexed for MEDLINE]
13.

Genomic profiling of adult acute lymphoblastic leukemia by single nucleotide polymorphism oligonucleotide microarray and comparison to pediatric acute lymphoblastic leukemia.

Okamoto R, Ogawa S, Nowak D, Kawamata N, Akagi T, Kato M, Sanada M, Weiss T, Haferlach C, Dugas M, Ruckert C, Haferlach T, Koeffler HP.

Haematologica. 2010 Sep;95(9):1481-8. doi: 10.3324/haematol.2009.011114. Epub 2010 Apr 30.

PMID:
20435627
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Cloning of genes involved in chromosomal translocations by high-resolution single nucleotide polymorphism genomic microarray.

Kawamata N, Ogawa S, Zimmermann M, Niebuhr B, Stocking C, Sanada M, Hemminki K, Yamatomo G, Nannya Y, Koehler R, Flohr T, Miller CW, Harbott J, Ludwig WD, Stanulla M, Schrappe M, Bartram CR, Koeffler HP.

Proc Natl Acad Sci U S A. 2008 Aug 19;105(33):11921-6. doi: 10.1073/pnas.0711039105. Epub 2008 Aug 12.

PMID:
18697940
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Wide diversity of PAX5 alterations in B-ALL: a Groupe Francophone de Cytogenetique Hematologique study.

Coyaud E, Struski S, Prade N, Familiades J, Eichner R, Quelen C, Bousquet M, Mugneret F, Talmant P, Pages MP, Lefebvre C, Penther D, Lippert E, Nadal N, Taviaux S, Poppe B, Luquet I, Baranger L, Eclache V, Radford I, Barin C, Mozziconacci MJ, Lafage-Pochitaloff M, Antoine-Poirel H, Charrin C, Perot C, Terre C, Brousset P, Dastugue N, Broccardo C.

Blood. 2010 Apr 15;115(15):3089-97. doi: 10.1182/blood-2009-07-234229. Epub 2010 Feb 16.

PMID:
20160164
[PubMed - indexed for MEDLINE]
Free Article
16.

The genetic basis of early T-cell precursor acute lymphoblastic leukaemia.

Zhang J, Ding L, Holmfeldt L, Wu G, Heatley SL, Payne-Turner D, Easton J, Chen X, Wang J, Rusch M, Lu C, Chen SC, Wei L, Collins-Underwood JR, Ma J, Roberts KG, Pounds SB, Ulyanov A, Becksfort J, Gupta P, Huether R, Kriwacki RW, Parker M, McGoldrick DJ, Zhao D, Alford D, Espy S, Bobba KC, Song G, Pei D, Cheng C, Roberts S, Barbato MI, Campana D, Coustan-Smith E, Shurtleff SA, Raimondi SC, Kleppe M, Cools J, Shimano KA, Hermiston ML, Doulatov S, Eppert K, Laurenti E, Notta F, Dick JE, Basso G, Hunger SP, Loh ML, Devidas M, Wood B, Winter S, Dunsmore KP, Fulton RS, Fulton LL, Hong X, Harris CC, Dooling DJ, Ochoa K, Johnson KJ, Obenauer JC, Evans WE, Pui CH, Naeve CW, Ley TJ, Mardis ER, Wilson RK, Downing JR, Mullighan CG.

Nature. 2012 Jan 11;481(7380):157-63. doi: 10.1038/nature10725.

PMID:
22237106
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

IKZF1 deletions predict a poor prognosis in children with B-cell progenitor acute lymphoblastic leukemia: a multicenter analysis in Taiwan.

Yang YL, Hung CC, Chen JS, Lin KH, Jou ST, Hsiao CC, Sheen JM, Cheng CN, Wu KH, Lin SR, Yu SL, Chen HY, Lu MY, Wang SC, Chang HH, Lin SW, Su YN, Lin DT.

Cancer Sci. 2011 Oct;102(10):1874-81. doi: 10.1111/j.1349-7006.2011.02031.x. Epub 2011 Aug 12.

PMID:
21740479
[PubMed - indexed for MEDLINE]
18.

Integration of genomic and gene expression data of childhood ALL without known aberrations identifies subgroups with specific genetic hallmarks.

Bungaro S, Dell'Orto MC, Zangrando A, Basso D, Gorletta T, Lo Nigro L, Leszl A, Young BD, Basso G, Bicciato S, Biondi A, te Kronnie G, Cazzaniga G.

Genes Chromosomes Cancer. 2009 Jan;48(1):22-38. doi: 10.1002/gcc.20616.

PMID:
18803328
[PubMed - indexed for MEDLINE]
19.

FOXP1 and PAX5 are rare but recurrent translocations partners in acute lymphoblastic leukemia.

Put N, Deeren D, Michaux L, Vandenberghe P.

Cancer Genet. 2011 Aug;204(8):462-4. doi: 10.1016/j.cancergen.2011.07.006.

PMID:
21962897
[PubMed - indexed for MEDLINE]
20.

Evaluation of PAX5 gene in the early stages of leukemic B cells in the childhood B cell acute lymphoblastic leukemia.

Firtina S, Sayitoglu M, Hatirnaz O, Erbilgin Y, Oztunc C, Cinar S, Yildiz I, Celkan T, Anak S, Unuvar A, Devecioglu O, Timur C, Aydogan G, Akcay A, Atay D, Turkkan E, Karaman S, Orhaner B, Sarper N, Deniz G, Ozbek U.

Leuk Res. 2012 Jan;36(1):87-92. doi: 10.1016/j.leukres.2011.07.017. Epub 2011 Aug 2.

PMID:
21813177
[PubMed - indexed for MEDLINE]

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