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Results: 1 to 20 of 122

1.

Lhx3, a LIM domain transcription factor, is regulated by Pou4f3 in the auditory but not in the vestibular system.

Hertzano R, Dror AA, Montcouquiol M, Ahmed ZM, Ellsworth B, Camper S, Friedman TB, Kelley MW, Avraham KB.

Eur J Neurosci. 2007 Feb;25(4):999-1005.

PMID:
17331196
[PubMed - indexed for MEDLINE]
2.

Transcription profiling of inner ears from Pou4f3(ddl/ddl) identifies Gfi1 as a target of the Pou4f3 deafness gene.

Hertzano R, Montcouquiol M, Rashi-Elkeles S, Elkon R, Yücel R, Frankel WN, Rechavi G, Möröy T, Friedman TB, Kelley MW, Avraham KB.

Hum Mol Genet. 2004 Sep 15;13(18):2143-53. Epub 2004 Jul 14.

PMID:
15254021
[PubMed - indexed for MEDLINE]
Free Article
3.

Essential role of POU-domain factor Brn-3c in auditory and vestibular hair cell development.

Xiang M, Gan L, Li D, Chen ZY, Zhou L, O'Malley BW Jr, Klein W, Nathans J.

Proc Natl Acad Sci U S A. 1997 Aug 19;94(17):9445-50.

PMID:
9256502
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Brn3c null mutant mice show long-term, incomplete retention of some afferent inner ear innervation.

Xiang M, Maklad A, Pirvola U, Fritzsch B.

BMC Neurosci. 2003 Jan 30;4:2.

PMID:
12585968
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Mutation in transcription factor POU4F3 associated with inherited progressive hearing loss in humans.

Vahava O, Morell R, Lynch ED, Weiss S, Kagan ME, Ahituv N, Morrow JE, Lee MK, Skvorak AB, Morton CC, Blumenfeld A, Frydman M, Friedman TB, King MC, Avraham KB.

Science. 1998 Mar 20;279(5358):1950-4.

PMID:
9506947
[PubMed - indexed for MEDLINE]
Free Article
6.

Barhl1 regulatory sequences required for cell-specific gene expression and autoregulation in the inner ear and central nervous system.

Chellappa R, Li S, Pauley S, Jahan I, Jin K, Xiang M.

Mol Cell Biol. 2008 Mar;28(6):1905-14. doi: 10.1128/MCB.01454-07. Epub 2008 Jan 22.

PMID:
18212062
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Brn-3c (POU4F3) regulates BDNF and NT-3 promoter activity.

Clough RL, Sud R, Davis-Silberman N, Hertzano R, Avraham KB, Holley M, Dawson SJ.

Biochem Biophys Res Commun. 2004 Nov 5;324(1):372-81.

PMID:
15465029
[PubMed - indexed for MEDLINE]
8.

Regulation of POU4F3 gene expression in hair cells by 5' DNA in mice.

Masuda M, Dulon D, Pak K, Mullen LM, Li Y, Erkman L, Ryan AF.

Neuroscience. 2011 Dec 1;197:48-64. doi: 10.1016/j.neuroscience.2011.09.033. Epub 2011 Sep 19.

PMID:
21958861
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Requirement for Brn-3c in maturation and survival, but not in fate determination of inner ear hair cells.

Xiang M, Gao WQ, Hasson T, Shin JJ.

Development. 1998 Oct;125(20):3935-46.

PMID:
9735355
[PubMed - indexed for MEDLINE]
Free Article
10.

Missense mutations in POU4F3 cause autosomal dominant hearing impairment DFNA15 and affect subcellular localization and DNA binding.

Collin RW, Chellappa R, Pauw RJ, Vriend G, Oostrik J, van Drunen W, Huygen PL, Admiraal R, Hoefsloot LH, Cremers FP, Xiang M, Cremers CW, Kremer H.

Hum Mutat. 2008 Apr;29(4):545-54. doi: 10.1002/humu.20693.

PMID:
18228599
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Hes1 is a negative regulator of inner ear hair cell differentiation.

Zheng JL, Shou J, Guillemot F, Kageyama R, Gao WQ.

Development. 2000 Nov;127(21):4551-60.

PMID:
11023859
[PubMed - indexed for MEDLINE]
Free Article
12.

Caprin-1 is a target of the deafness gene Pou4f3 and is recruited to stress granules in cochlear hair cells in response to ototoxic damage.

Towers ER, Kelly JJ, Sud R, Gale JE, Dawson SJ.

J Cell Sci. 2011 Apr 1;124(Pt 7):1145-55. doi: 10.1242/jcs.076141.

PMID:
21402877
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

A defect in harmonin, a PDZ domain-containing protein expressed in the inner ear sensory hair cells, underlies Usher syndrome type 1C.

Verpy E, Leibovici M, Zwaenepoel I, Liu XZ, Gal A, Salem N, Mansour A, Blanchard S, Kobayashi I, Keats BJ, Slim R, Petit C.

Nat Genet. 2000 Sep;26(1):51-5.

PMID:
10973247
[PubMed - indexed for MEDLINE]
14.

Anti-apoptotic factor z-Val-Ala-Asp-fluoromethylketone promotes the survival of cochlear hair cells in a mouse model for human deafness.

Atar O, Avraham KB.

Neuroscience. 2010 Jul 14;168(3):851-7. doi: 10.1016/j.neuroscience.2010.04.011. Epub 2010 Apr 13.

PMID:
20394804
[PubMed - indexed for MEDLINE]
15.

Molecular modelling insights into DFNA15 mediated enhancement of POU4F3 stability.

Frenz CM, Lefebvre PP.

Int J Comput Biol Drug Des. 2008;1(3):295-301.

PMID:
20054994
[PubMed - indexed for MEDLINE]
16.

Developmental expression of the POU domain transcription factor Brn-3b (Pou4f2) in the lateral line and visual system of zebrafish.

DeCarvalho AC, Cappendijk SL, Fadool JM.

Dev Dyn. 2004 Apr;229(4):869-76.

PMID:
15042710
[PubMed - indexed for MEDLINE]
Free Article
17.

Reduced expression of the LIM-homeobox gene Lhx3 impairs growth and differentiation of Rathke's pouch and increases cell apoptosis during mouse pituitary development.

Zhao Y, Morales DC, Hermesz E, Lee WK, Pfaff SL, Westphal H.

Mech Dev. 2006 Aug;123(8):605-13. Epub 2006 Jun 14.

PMID:
16859901
[PubMed - indexed for MEDLINE]
Free Article
18.

Mild and variable audiometric and vestibular features in a third DFNA15 family with a novel mutation in POU4F3.

de Heer AM, Huygen PL, Collin RW, Kremer H, Cremers CW.

Ann Otol Rhinol Laryngol. 2009 Apr;118(4):313-20.

PMID:
19462854
[PubMed - indexed for MEDLINE]
19.

The DFNA15 deafness mutation affects POU4F3 protein stability, localization, and transcriptional activity.

Weiss S, Gottfried I, Mayrose I, Khare SL, Xiang M, Dawson SJ, Avraham KB.

Mol Cell Biol. 2003 Nov;23(22):7957-64.

PMID:
14585957
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Prox1 interacts with Atoh1 and Gfi1, and regulates cellular differentiation in the inner ear sensory epithelia.

Kirjavainen A, Sulg M, Heyd F, Alitalo K, Ylä-Herttuala S, Möröy T, Petrova TV, Pirvola U.

Dev Biol. 2008 Oct 1;322(1):33-45. doi: 10.1016/j.ydbio.2008.07.004. Epub 2008 Jul 9.

PMID:
18652815
[PubMed - indexed for MEDLINE]
Free Article

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