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Items: 1 to 20 of 111

1.

Dickkopf-1 is an epigenetically silenced candidate tumor suppressor gene in medulloblastoma.

Vibhakar R, Foltz G, Yoon JG, Field L, Lee H, Ryu GY, Pierson J, Davidson B, Madan A.

Neuro Oncol. 2007 Apr;9(2):135-44. Epub 2007 Feb 28.

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Identification of genes up-regulated by histone deacetylase inhibition with cDNA microarray and exploration of epigenetic alterations on hepatoma cells.

Chiba T, Yokosuka O, Arai M, Tada M, Fukai K, Imazeki F, Kato M, Seki N, Saisho H.

J Hepatol. 2004 Sep;41(3):436-45.

PMID:
15336447
4.

The SFRP family of WNT inhibitors function as novel tumor suppressor genes epigenetically silenced in medulloblastoma.

Kongkham PN, Northcott PA, Croul SE, Smith CA, Taylor MD, Rutka JT.

Oncogene. 2010 May 20;29(20):3017-24. doi: 10.1038/onc.2010.32. Epub 2010 Mar 8.

PMID:
20208569
5.
6.

Overexpressed TP73 induces apoptosis in medulloblastoma.

Castellino RC, De Bortoli M, Lin LL, Skapura DG, Rajan JA, Adesina AM, Perlaky L, Irwin MS, Kim JY.

BMC Cancer. 2007 Jul 12;7:127.

7.

Induction of ID1 expression and apoptosis by the histone deacetylase inhibitor (trichostatin A) in human acute myeloid leukaemic cells.

Yu WP, Scott SA, Dong WF.

Cell Prolif. 2008 Feb;41(1):86-97. doi: 10.1111/j.1365-2184.2007.00499.x.

PMID:
18211287
8.

An epigenetic genome-wide screen identifies SPINT2 as a novel tumor suppressor gene in pediatric medulloblastoma.

Kongkham PN, Northcott PA, Ra YS, Nakahara Y, Mainprize TG, Croul SE, Smith CA, Taylor MD, Rutka JT.

Cancer Res. 2008 Dec 1;68(23):9945-53. doi: 10.1158/0008-5472.CAN-08-2169.

9.

Anti-arthritic effects of combined treatment with histone deacetylase inhibitor and low-intensity ultrasound in the presence of microbubbles in human rheumatoid synovial cells.

Nakamura C, Matsushita I, Kosaka E, Kondo T, Kimura T.

Rheumatology (Oxford). 2008 Apr;47(4):418-24. doi: 10.1093/rheumatology/ken003. Epub 2008 Feb 15.

10.

Monochromosome transfer and microarray analysis identify a critical tumor-suppressive region mapping to chromosome 13q14 and THSD1 in esophageal carcinoma.

Ko JM, Chan PL, Yau WL, Chan HK, Chan KC, Yu ZY, Kwong FM, Miller LD, Liu ET, Yang LC, Lo PH, Stanbridge EJ, Tang JC, Srivastava G, Tsao SW, Law S, Lung ML.

Mol Cancer Res. 2008 Apr;6(4):592-603. doi: 10.1158/1541-7786.MCR-07-0154.

11.

Molecular profiling of embryonal carcinoma cells following retinoic acid or histone deacetylase inhibitor treatment.

Sangster-Guity N, Yu LM, McCormick P.

Cancer Biol Ther. 2004 Nov;3(11):1109-20. Epub 2004 Nov 24.

PMID:
15467438
12.

EMP3, a myelin-related gene located in the critical 19q13.3 region, is epigenetically silenced and exhibits features of a candidate tumor suppressor in glioma and neuroblastoma.

Alaminos M, Dávalos V, Ropero S, Setién F, Paz MF, Herranz M, Fraga MF, Mora J, Cheung NK, Gerald WL, Esteller M.

Cancer Res. 2005 Apr 1;65(7):2565-71.

13.

Histone deacetylase inhibitor trichostatin a potentiates doxorubicin-induced apoptosis by up-regulating PTEN expression.

Pan L, Lu J, Wang X, Han L, Zhang Y, Han S, Huang B.

Cancer. 2007 Apr 15;109(8):1676-88.

14.

Histone deacetylase inhibitors cooperate with IFN-gamma to restore caspase-8 expression and overcome TRAIL resistance in cancers with silencing of caspase-8.

Häcker S, Dittrich A, Mohr A, Schweitzer T, Rutkowski S, Krauss J, Debatin KM, Fulda S.

Oncogene. 2009 Sep 3;28(35):3097-110. doi: 10.1038/onc.2009.161. Epub 2009 Jul 13.

PMID:
19597472
15.

Dickkopf-1 is down-regulated by MYCN and inhibits neuroblastoma cell proliferation.

Koppen A, Ait-Aissa R, Hopman S, Koster J, Haneveld F, Versteeg R, Valentijn LJ.

Cancer Lett. 2007 Oct 28;256(2):218-28. Epub 2007 Jul 23.

PMID:
17643814
16.

Wnt signalling in human breast cancer: expression of the putative Wnt inhibitor Dickkopf-3 (DKK3) is frequently suppressed by promoter hypermethylation in mammary tumours.

Veeck J, Bektas N, Hartmann A, Kristiansen G, Heindrichs U, Knüchel R, Dahl E.

Breast Cancer Res. 2008;10(5):R82. doi: 10.1186/bcr2151. Epub 2008 Sep 30.

17.

Antitumor activity of histone deacetylase inhibitors in non-small cell lung cancer cells: development of a molecular predictive model.

Miyanaga A, Gemma A, Noro R, Kataoka K, Matsuda K, Nara M, Okano T, Seike M, Yoshimura A, Kawakami A, Uesaka H, Nakae H, Kudoh S.

Mol Cancer Ther. 2008 Jul;7(7):1923-30. doi: 10.1158/1535-7163.MCT-07-2140. Epub 2008 Jul 7.

18.

PCDH10 is a candidate tumour suppressor gene in medulloblastoma.

Bertrand KC, Mack SC, Northcott PA, Garzia L, Dubuc A, Pfister SM, Rutka JT, Weiss WA, Taylor MD.

Childs Nerv Syst. 2011 Aug;27(8):1243-9. doi: 10.1007/s00381-011-1486-x. Epub 2011 May 20.

PMID:
21597995
19.

SLC5A8 triggers tumor cell apoptosis through pyruvate-dependent inhibition of histone deacetylases.

Thangaraju M, Gopal E, Martin PM, Ananth S, Smith SB, Prasad PD, Sterneck E, Ganapathy V.

Cancer Res. 2006 Dec 15;66(24):11560-4.

20.

Effects of trichostatin A, a histone deacetylase inhibitor, on the regulation of apoptosis in H-ras-transformed breast epithelial cells.

Park H, Lee YJ, Kim TH, Lee J, Yoon S, Choi WS, Myung CS, Kim HS.

Int J Mol Med. 2008 Nov;22(5):605-11.

PMID:
18949380
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